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Keywords: RNAi
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Biochem Soc Trans (2023) 51 (1): 21–29.
Published: 11 January 2023
... kill cells through the activity of sRNAs derived from its mRNA in the RISC. In fact, the expression of abundant CD95L-derived sequences as siRNAs demonstrated that some CD95L sequences exerted high levels of toxicity to cells through RNAi. One of these toxic abundant sequences was nearly identical...
Biochem Soc Trans (2017) 45 (5): 1117–1124.
Published: 22 September 2017
... produced by RNase III Dicer. miRNAs are genome-encoded post-transcriptional regulators of gene expression produced from small hairpins usually hosted in long RNA precursors (reviewed in refs [ 31 , 32 ]). siRNAs are produced from long double-stranded RNA (dsRNA) and act in RNA interference (RNAi). RNAi...