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Keywords: RNAi
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Cell death and survival
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 21–29.
Published: 11 January 2023
... kill cells through the activity of sRNAs derived from its mRNA in the RISC. In fact, the expression of abundant CD95L-derived sequences as siRNAs demonstrated that some CD95L sequences exerted high levels of toxicity to cells through RNAi. One of these toxic abundant sequences was nearly identical...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (5): 1117–1124.
Published: 22 September 2017
... produced by RNase III Dicer. miRNAs are genome-encoded post-transcriptional regulators of gene expression produced from small hairpins usually hosted in long RNA precursors (reviewed in refs [ 31 , 32 ]). siRNAs are produced from long double-stranded RNA (dsRNA) and act in RNA interference (RNAi). RNAi...
