...://creativecommons.org/licenses/by-nc/2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. extracellular small RNA microRNA (miRNA) RNA RNA-induced silencing complex (RISC) Mandel and Métais first described...

... than expected. The present paper reviews the different approaches to predict and experimentally identify genes targeted by miRNAs. antimir antagomir microRNA (miRNA) RNA-induced silencing complex (RISC) target prediction program 1 email t.dalmay@uea.ac.uk 9 9 2008 ©...

... on accessibility was determined. For all G/C classes, even for G/C content >60%, we could significantly separate functional and non-functional siRNAs. 4 7 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 cleavage microRNA (miRNA) RNA-induced silencing complex (RISC...

... methylation miRNA RNA-induced silencing complex (RISC) siRNA The ability to process double-stranded RNA into small 21–28 nt fragments by an RNaseIII-based enzyme called Dicer [or Dicer-like (DCL)] is widespread among eukaryotic cells. The products of cleavage, termed siRNA ( s hort i nterfering...