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Keywords: RNA processing
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Articles
Biochem Soc Trans (2022) 50 (5): 1447–1456.
Published: 25 October 2022
...Katherine L.B. Borden Typically, cancer is thought to arise due to DNA mutations, dysregulated transcription and/or aberrant signalling. Recently, it has become clear that dysregulated mRNA processing, mRNA export and translation also contribute to malignancy. RNA processing events result in major...
Articles
Biochem Soc Trans (2013) 41 (6): 1660–1665.
Published: 20 November 2013
.... 1 To whom correspondence should be addressed (email miriam.sanso@mssm.edu ). 8 10 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 cyclin-dependent kinase (CDK) fission yeast histone mark RNA polymerase II transcription RNA processing...
Articles
Biochem Soc Trans (2013) 41 (6): 1459–1463.
Published: 20 November 2013
... regularly interspaced short palindromic repeats (CRISPR) RNA processing RNA-Seq The investigation of crRNA abundance and processing patterns from several organisms using RNA-Seq methodology has demonstrated that single spacer sequences can have an extensive impact on pre-crRNA transcription...
Articles
Biochem Soc Trans (2012) 40 (4): 850–855.
Published: 20 July 2012
... role in RNA processing/degradation and discuss important new insights into exosome composition and function in human cells. 1 To whom correspondence should be addressed (email n.j.watkins@ncl.ac.uk ). 2 3 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012...
Articles
Biochem Soc Trans (2012) 40 (4): 773–777.
Published: 20 July 2012
..., at least 13 different mRNAs with the capacity to encode capsid proteins are produced by alternative splicing [ 12 ]. During differentiation of uninfected keratinocytes, levels of RNA-processing factors either do not change significantly or decrease [ 25 ]. In contrast, a number of cellular splicing...
Articles
Biochem Soc Trans (2012) 40 (4): 880–885.
Published: 20 July 2012
.... 1 To whom correspondence should be addressed (email b.mueller@abdn.ac.uk ). 20 3 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 cell cycle DNA replication histone gene expression RNA degradation RNA processing translation The packaging...
Articles
Biochem Soc Trans (2010) 38 (6): 1500–1505.
Published: 24 November 2010
... ). 7 6 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 gene expression nonsense-mediated mRNA decay (NMD) premature termination codon (PTC) RNA decay RNA processing RNA quality control Severo Ochoa won the 1959 Nobel Prize in Medicine after he...
Articles
Biochem Soc Trans (2010) 38 (4): 1125–1130.
Published: 26 July 2010
... ancestor with a diverse set of spliced leader RNA genes. 1 To whom correspondence should be addressed (email b.mueller@abdn.ac.uk ). 26 2 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 eukaryote gene expression metazoan RNA processing RNA splicing...
Articles
Biochem Soc Trans (2010) 38 (4): 1093–1098.
Published: 26 July 2010
... RNAs and a few proteins. Biogenesis pathways of all RNPs are, however, similar in many respects, and most involve multiple steps and factors. RNA processing steps are intimately linked into the assembly of many RNPs, with endo- and/or exo-nucleases removing portions of the primary transcript...
Articles
Biochem Soc Trans (2010) 38 (1): 217–222.
Published: 19 January 2010
.../SkIP-associated RNA processing) complex as a co-transcriptional regulator of cyclin D1 RNA stability. In addition to transcriptional regulation, cells employ a vast array of post-transcriptional mechanisms that can rapidly modulate cyclin D1 activity, to allow appropriate cell cycle progression...
Articles
Biochem Soc Trans (2008) 36 (4): 590–594.
Published: 22 July 2008
... promoter-specific recognition of the 3′-box RNA processing signal requires a novel phosphorylation mark on the pol II CTD. This new mark plays a critical role in the recruitment of the snRNA gene-specific RNA-processing complex, Integrator. These new findings provide the first example of a phosphorylation...
Articles
Biochem Soc Trans (2008) 36 (3): 505–507.
Published: 21 May 2008
.... 1 To whom correspondence should be addressed (email prabs_rajan@yahoo.co.uk ). 21 1 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 cancer cell cycle RNA processing signal transducer and activator of RNA (STAR) Src-associated in mitosis 68 kDa (Sam68...
Articles
Biochem Soc Trans (2008) 36 (3): 537–539.
Published: 21 May 2008
... -Ser 5 -Pro 6 -Ser 7 . This domain is now known to play a major role in the processes of transcription and co-transcriptional RNA processing in expression of both snRNA and protein-coding genes. The heptapeptide repeat unit can be extensively modified in vivo and covalent modifications of the CTD...
Articles
Biochem Soc Trans (2006) 34 (6): 1145–1147.
Published: 25 October 2006
... exist to prevent their expression in these cells. Indeed, a number of cis -acting RNA elements have been observed within the HPV-16 late region which may be involved in control of capsid gene expression. Mechanisms controlling HPV-16 capsid gene expression and the cellular RNA-processing factors...
Articles
Biochem Soc Trans (2005) 33 (3): 443–446.
Published: 01 June 2005
... of post-transcriptional gene expression. 1 To whom correspondence should be addressed (email Javier.Caceres@hgu.mrc.ac.uk ). 13 1 2005 © 2005 The Biochemical Society 2005 alternative splicing pre-mRNA splicing RNA processing RS domain small nuclear ribonucleoprotein (RNP...
Articles
Biochem Soc Trans (2005) 33 (3): 479–481.
Published: 01 June 2005
...S.C. Walker; T.V. Aspinall; J.M.B. Gordon; J.M. Avis In yeast, RNase MRP (mitochondrial RNA processing), a ribonucleoprotein precursor rRNA processing enzyme, possesses one putatively catalytic RNA and ten protein subunits and is highly related to RNase P. Structural analysis of the MRP RNA...