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Keywords: RNA localizationClose
Biochem Soc Trans (2021) 49 (6): 2591–2600.
Published: 25 November 2021
... by which cells can generate subcellular microenvironments with specialized gene expression profiles. Particularly intriguing are recent findings that phase separation plays a role in certain RNA localization pathways. The burgeoning field of phase separation has revolutionized how we view cellular...
Biochem Soc Trans (2021) 49 (5): 2221–2227.
Published: 08 September 2021
... change. local translation neuron RNA localization single-molecule Neurons are uniquely specialized cells, both morphologically and functionally. The elaborate arborisations of axons and dendrites overwhelmingly dominate a neuron's volume, and they can project relatively long distances away...
Biochem Soc Trans (2016) 44 (5): 1185–1200.
Published: 19 October 2016
... disordered proteins protein turnover RNA localization Understanding how proteins, which are polymers of amino acids, carry out different functions in a cell has been a problem of considerable interest. In a series of elegant publications, Christian Anfinsen and colleagues proposed that the sequence...
Biochem Soc Trans (2008) 36 (3): 540–542.
Published: 21 May 2008
... of gene expression in the testis yields information regarding both temporal and cell-type-specific regulation of transcription. As cells in the testis are large, transcripts with specific subcellular RNA localizations are readily identified. The primary spermatocyte period is characterized by high...