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Keywords: RNA degradation
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Articles
Biochem Soc Trans (2016) 44 (5): 1377–1384.
Published: 19 October 2016
...Amy L. Pashler; Benjamin P. Towler; Christopher I. Jones; Sarah F. Newbury RNA degradation is a vital post-transcriptional process which ensures that transcripts are maintained at the correct level within the cell. DIS3L2 and XRN1 are conserved exoribonucleases that are critical for the degradation...
Articles
Biochem Soc Trans (2016) 44 (5): 1475–1482.
Published: 19 October 2016
... in this organelle remain largely elusive. Here, we summarize the present knowledge of how RNA is degraded in human mitochondria and describe the coexistence of stable poly(A) tails and the nonabundant tails, which have been suggested to play a role in the RNA degradation process. Correspondence: Gadi Schuster...
Articles
Biochem Soc Trans (2012) 40 (4): 850–855.
Published: 20 July 2012
... exonuclease exosome RNA degradation RNA processing RNA surveillance Figure 3 Model of subcellular localization of different forms of the human exosome and cofactors The core exosome is shown in blue and purple. The PIN domains of DIS3 (active-small ‘pacman’) and DIS3L1 (inactive-small circle...
Articles
Biochem Soc Trans (2012) 40 (4): 836–841.
Published: 20 July 2012
...Jonathan Houseley Unstable non-coding RNAs are produced from thousands of loci in all studied eukaryotes (and also prokaryotes), but remain of largely unknown function. The present review summarizes the mechanisms of eukaryotic non-coding RNA degradation and highlights recent findings regarding...
Articles
Biochem Soc Trans (2012) 40 (4): 880–885.
Published: 20 July 2012
.... 1 To whom correspondence should be addressed (email b.mueller@abdn.ac.uk ). 20 3 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 cell cycle DNA replication histone gene expression RNA degradation RNA processing translation The packaging...
Articles
Biochem Soc Trans (2009) 37 (1): 83–87.
Published: 20 January 2009
... exosome helicase polyadenylation RNA degradation The variety and amount of RNA molecules that are produced in a cell is remarkable. There are mRNAs from thousands of genes as well as many RNA molecules that are not translated into proteins and function directly as RNAs. These non-coding RNAs...