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Keywords: PtdIns(3,4,5)P3
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Biochem Soc Trans (2004) 32 (2): 338–342.
Published: 01 April 2004
... messengers, especially PtdIns(3,4,5)P3. Cellular PTEN activity is restrained by the retention of C-terminally phosphorylated enzyme in the cytosol. Dephosphorylation by as yet undefined phosphatases initiates an electrostatic switch which targets PTEN specifically to the plasma membrane, where it binds...
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Biochem Soc Trans (1997) 25 (2): 241S.
Published: 01 May 1997
...JULIE D. McLEOD; LUCY S. K. WALKER; RICHARD V. PARRY; STEPHEN G. WARD; DAVID M. SANSOM © 1997 Biochemical Society 1997 Fas-L, Fas Ligand mAb, monoclonal antibody ND, not determined PtdIns(3,4,5) P3 PI3K, phosphatidylinositol 3-kinase PTK, protein tyrosine kinase 660th...