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Keywords: PtdIns(3,4,5)P3
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Biochem Soc Trans (2004) 32 (2): 338–342.
Published: 01 April 2004
... 5EH, U.K. Abstract PTEN (phosphatase and tensin homologue deleted on chromosome 10) is a member of the protein tyrosine phosphatase family that is structurally adapted to facilitate the metabolism of 3-phosphoinositide lipid second messengers, especially PtdIns(3,4,5)P3. Cellular PTEN activity...
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