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Keywords: PtdIns(3,4,5)P3
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Biochem Soc Trans (2004) 32 (2): 338–342.
Published: 01 April 2004
... messengers, especially PtdIns(3,4,5)P3. Cellular PTEN activity is restrained by the retention of C-terminally phosphorylated enzyme in the cytosol. Dephosphorylation by as yet undefined phosphatases initiates an electrostatic switch which targets PTEN specifically to the plasma membrane, where it binds...
Biochem Soc Trans (1997) 25 (2): 241S.
Published: 01 May 1997
...JULIE D. McLEOD; LUCY S. K. WALKER; RICHARD V. PARRY; STEPHEN G. WARD; DAVID M. SANSOM © 1997 Biochemical Society 1997 Fas-L, Fas Ligand mAb, monoclonal antibody ND, not determined PtdIns(3,4,5) P3 PI3K, phosphatidylinositol 3-kinase PTK, protein tyrosine kinase 660th...