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Keywords: Polycomb repressive complex 2
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Biochem Soc Trans (2021) 49 (3): 1159–1170.
Published: 01 June 2021
... and the Biochemical Society under a transformative agreement with CAUL. chromatin reader DNA methylation gene repression histone modifications polycomb repressive complex 2 PRC2 Chromatin structure and epigenetic context are crucial regulatory factors for gene expression in eukaryotes. Chromatin...
Biochem Soc Trans (2021) 49 (1): 71–77.
Published: 22 February 2021
...Cecilia Lövkvist; Martin Howard The Polycomb system is essential for stable gene silencing in many organisms. This regulation is achieved in part through addition of the histone modifications H3K27me2/me3 by Polycomb Repressive Complex 2 (PRC2). These modifications are believed to be the causative...
Biochem Soc Trans (2020) 48 (6): 2779–2789.
Published: 10 November 2020
...Jie Shu; Chen Chen; Chenlong Li; Yuhai Cui Polycomb repressive complex 2 (PRC2) is an evolutionally conserved multisubunit complex essential for the development of eukaryotes. In Arabidopsis thaliana ( Arabidopsis ), CURLY LEAF (CLF) and SWINGER (SWN) are PRC2 catalytic subunits that repress gene...
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Biochem Soc Trans (2019) 47 (4): 1187–1196.
Published: 05 July 2019
...Silvia Costa; Caroline Dean Polycomb-mediated epigenetic silencing is central to correct growth and development in higher eukaryotes. The evolutionarily conserved Polycomb repressive complex 2 (PRC2) transcriptionally silences target genes through a mechanism requiring the histone modification...