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Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (3): 845–854.
Published: 15 June 2017
.... The ESCRT member HD-PTP/ PTPN23 was recently identified as a novel haplo-insufficient tumour suppressor in vitro and in vivo , in mice and humans. In this mini-review, we outline the role of the ESCRT components in cancer and summarize the functions of HD-PTP/ PTPN23 in tumorigenesis. Cell surface...