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Keywords: PREX1
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Biochem Soc Trans (2017) 45 (4): 963–977.
Published: 14 July 2017
... compared with normal melanocytes or NRAS -/ BRAF -wild-type cell lines [ 13 , 14 ], suggesting subset-specific involvement of P-Rex1 in melanoma. Interestingly, the in vivo role P-Rex1 plays in melanoma metastasis has been examined experimentally by crossing Prex1 −/− mice with an Nras Q61K -driven...