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Keywords: PINK1
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Biochem Soc Trans (2016) 44 (6): 1717–1724.
Published: 02 December 2016
...-induced putative kinase 1 (PINK1)–Pakin activates protein synthesis on damaged mitochondria to maintain the organelle homeostasis and activity. We also summarize some recent progress on miRNAs' regulation on mitochondrial biogenesis. Correspondence: Hong Xu ( hong.xu@nih.gov ) 10 3 2016 30...
Biochem Soc Trans (2015) 43 (4): 602–610.
Published: 03 August 2015
...; published by Portland Press Limited 2015 cytoprotection FRET/FLIM mitochondria PINK1 redox The transcription factor NF-E2 p45-related factor 2 (Nrf2, gene name NFE2L2 ) and its negative regulator Kelch-like ECH associated protein 1 (Keap1) control the expression of large networks of genes...
Biochem Soc Trans (2015) 43 (2): 302–307.
Published: 07 April 2015
... protein, provide a clear research target in iPSC-derived neurons. Recessively inherited Parkin and PTEN-induced putative kinase 1 (PINK1) mutations have been investigated in this context and the present review describes the first insights gained from studies in iPSC-derived dopaminergic neurons, which...
Biochem Soc Trans (2015) 43 (2): 275–279.
Published: 07 April 2015
... melanogaster showing that stimulation of the electron transport chain is beneficial for PD fly models showing Complex I defects and discuss the possible clinical applications of these findings. electron transport chain mitochondria Parkinson's disease Pink1 vitamin K 2 Parkinson's disease (PD...