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Keywords: OGG1
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Biochem Soc Trans (2022) 50 (5): 1481–1488.
Published: 28 October 2022
... of 8-oxoG. This review first discusses biochemical studies demonstrating how UV-DDB stimulates human 8-oxoG glycosylase (OGG1), MUTYH, and apurinic/apyrimidinic (AP) endonuclease (APE1) to increase their turnover at damage sites. We further discuss our single-molecule studies showing that UV-DDB...