...Liping Zhang; Kelly G. Ten Hagen Glycosylation is one of the most abundant protein modifications in Nature, having roles in protein stability, secretion and function. Alterations in mucin-type O-glycosylation are responsible for a number of human diseases and developmental defects, as well...

.... 1 To whom correspondence should be addressed (email M.C.Galan@bristol.ac.uk ). 15 3 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 ionic liquid mucin mucin function mucin glycan O-glycosylation oligosaccharide synthesis Mucosal tissues...

...G. Patsos; C. Robbe-Masselot; A. Klein; V. Hebbe-Viton; R. San Martin; D. Masselot; M. Graessmann; C. Paraskeva; T. Gallagher; A. Corfield Cell growth pathways are mediated through protein–glycan interactions including O-glycosylation. Investigation of these growth pathways can be carried out using...

...G. Patsos; V. Hebbe-Viton; R. San Martin; C. Paraskeva; T. Gallagher; A. Corfield O-glycosylation is thought to play a significant role in the regulation of cell growth. However, only limited information is available, and few specific and selective inhibitors have been found. We have synthesized...