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Keywords: O-GlcNAcylation
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Biochem Soc Trans (2022) 50 (6): 1693–1702.
Published: 16 November 2022
... are almost always associated with severe neurological abnormalities, suggesting that glycosylation plays an essential role in early brain development. Congenital disorders of O -GlcNAcylation are no exception, and all mutations of the O -GlcNAc transferase (OGT) are associated with X-linked intellectual...
Biochem Soc Trans (2017) 45 (2): 365–370.
Published: 13 April 2017
...Moyira Aquino-Gil; Annick Pierce; Yobana Perez-Cervera; Edgar Zenteno; Tony Lefebvre O -GlcNAcylation is a highly dynamic post-translational modification whose level depends on nutrient status. Only two enzymes regulate O -GlcNAcylation cycling, the glycosyltransferase OGT ( O -GlcNAc transferase...