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Keywords: Mycobacterium tuberculosis
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Biochem Soc Trans (2023) 51 (1): 183–193.
Published: 20 January 2023
... chain membrane proteins Mycobacterium tuberculosis protein structure Bacteria of the genus Mycobacterium include pathogenic species such as M. tuberculosis , M. leprae , M. avium , M. abscessus (sometimes called Mycobacteroides abscessus ), and M. ulcerans, as well as non-pathogenic...
Biochem Soc Trans (2019) 47 (4): 1091–1099.
Published: 27 June 2019
...@ucl.ac.uk ) 5 3 2019 10 5 2019 28 5 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 expression platform Gram-negative bacteria Gram-positive bacteria Mycobacterium tuberculosis riboswitches termination...
Biochem Soc Trans (2019) 47 (3): 847–860.
Published: 13 May 2019
...). Published by Portland Press Limited on behalf of the Biochemical Society 2019 antimicrobials bacteriophages Mycobacterium tuberculosis RNA polymerase transcription The current first-line treatment of drug-sensitive TB (DS-TB) involves a 6-month course of rifampicin (inhibition of bacterial...
Biochem Soc Trans (2016) 44 (1): 68–73.
Published: 09 February 2016
...Stephen Bornemann It has long been reported that Mycobacterium tuberculosis is capable of synthesizing the α-glucan glycogen. However, what makes this bacterium stand out is that it coats itself in a capsule that mainly consists of a glycogen-like α-glucan. This polymer helps the pathogen evade...
Biochem Soc Trans (2010) 38 (5): 1286–1289.
Published: 24 September 2010
...Dany J.V. Beste; Johnjoe McFadden Despite decades of research, many aspects of the biology of Mycobacterium tuberculosis remain unclear, and this is reflected in the antiquated tools available to treat and prevent tuberculosis and consequently this disease remains a serious public health problem...
Biochem Soc Trans (2009) 37 (2): 333–335.
Published: 20 March 2009
... 2009 enzymology hydrogen tunnelling kinetics Mycobacterium tuberculosis nitric oxide synthase (NOS) quantum mechanics/molecular mechanics (QM/MM) Was there ever a time when enzymology and its development were so important to the progression of the biological sciences? With an explosion...
Biochem Soc Trans (2008) 36 (4): 555–565.
Published: 22 July 2008
... Mycobacterium tuberculosis mycolic acid Figure 2 Schematic representation of the lipoarabinomannan (LAM) biosynthesis pathway in mycobacteria GT-C, glycosyltransferase family C enzyme; PI, phosphatidylinositol; PP, polyprenyl phosphate. Recent studies have elucidated a number of the key...
Biochem Soc Trans (2005) 33 (4): 802–805.
Published: 01 August 2005
... and MS. Because Mycobacterium tuberculosis DAPA AT is a potential drug target, this enzyme was cloned, overexpressed and purified to homogeneity for biochemical characterization. Inactivation of Escherichia coli DAPA AT by amiclenomycin and analogues was carefully studied using different approaches...
Biochem Soc Trans (2003) 31 (3): 520–522.
Published: 01 June 2003
... representative chromosomally encoded aminoglycoside N-acetyltransferases, Mycobacterium tuberculosis AAC(2´)-Ic and Salmonella enterica AAC(6´)-Iy, and speculate about their possible physiological function and substrates. 1 To whom correspondence should be addressed (e-mail blanchar@aecom.yu.edu...