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Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (1): 44–46.
Published: 22 January 2007
... strategies have been proposed to improve siRNA delivery, their applications in vivo remain a major challenge. We have developed a new strategy, based on a short amphipathic peptide, MPG, that is able to form stable nanoparticles with siRNA. MPG-based particles enter the cell independently of the endosomal...