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Keywords: MAP kinase, mitogen-activated protein kinase
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Articles

Complexities in ETS-Domain Transcription Factor Function and Regulation: Lessons from the TCF (Ternary Complex Factor) Subfamily

A. D. Sharrocks
Journal: Biochemical Society Transactions
Biochem Soc Trans (2002) 30 (2): 1–9.
https://doi.org/10.1042/bst0300001
Published: 01 April 2002
... HDAC, histone deacetylase JNK, c-Jun N-terminal kinase MAP kinase, mitogen-activated protein kinase NID, Net inhibitory domain SRE, serum response element SRF, serum response factor SAP, SRF accessory protein TAD, transcriptional activation domain TCF, ternary complex factor Elk-1 MAP...
View article titled, Complexities in ETS-Domain Transcription Factor Function and Regulation: Lessons from the TCF (Ternary Complex Factor) Subfamily
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Articles

Role of Src in Signal Transduction Pathways

S. A. Courtneidge
Journal: Biochemical Society Transactions
Biochem Soc Trans (2002) 30 (2): 11–17.
https://doi.org/10.1042/bst0300011
Published: 01 April 2002
.... 1 e-mail sara.courtneidge@vai.org 19 12 2001 © 2002 Biochemical Society 2002 large T, large T antigen MAP kinase, mitogen-activated protein kinase PDGF, platelet-derived growth factor PTB domain, phosphotyrosine-binding domain SH2(3), Src homology 2(3) domain cancer...
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Articles

Caveolin-I, a putative tumour suppressor gene

B. Razani, A. Schlegel, J. Liu, M. P. Lisanti
Journal: Biochemical Society Transactions
Biochem Soc Trans (2001) 29 (4): 494–499.
https://doi.org/10.1042/bst0290494
Published: 01 August 2001
.... 1 To whom correspondence should be addressed (e-mail lisanti@aecom.yu.edu ) 26 2 2001 © 2001 Biochemical Society 2001 caveolae cell transformation D7S522/7q31.1 signal transduction EGF, epidermal growth factor MAP kinase, mitogen-activated protein kinase PI 3-kinase...
View article titled, Caveolin-I, a putative tumour suppressor gene
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Articles

Role of endocytosis in signalling and regulation of G-protein-coupled receptors

M. von Zastrow
Journal: Biochemical Society Transactions
Biochem Soc Trans (2001) 29 (4): 500–504.
https://doi.org/10.1042/bst0290500
Published: 01 August 2001
... in the cytoplasm which, in turn, regulate various downstream effectors. In addition to this 'classi- Key words: P2-adrenergic receptor, down-regulation, GPCR sequestration, traficking. Abbreviations used: &AR; a-adrenergic receptor; GPCR, G- protein-coupled receptor: MAP kinase, mitogen-activated protein kinase...
View article titled, Role of endocytosis in signalling and regulation of G-protein-coupled receptors
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Articles

Prolactin receptor heterogeneity: processing and signalling of the long and short isoforms during development

L. A. Schuler, J.-C. Lu, J. L. Brockman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2001) 29 (2): 52–56.
https://doi.org/10.1042/bst0290052
Published: 01 May 2001
... the importance of the JAK/STAT (Janus Key words: cyclin D I, internalization, JAWSTAT, placental lactogen. Abbreviations used: GH, growth hormone: GHR GH receptor; JAK, Janus kinase; MAP kinase, mitogen-activated protein kinase; PL placental lactogen; PRL prolactin; PRLR PRL receptor; IPRLR and sPRLR long...
View article titled, Prolactin receptor heterogeneity: processing and signalling of the long and short isoforms during development
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Articles

Role of reactive oxygen species in cell signalling pathways

J. T. Hancock, R. Desikan, S.J. Neill
Journal: Biochemical Society Transactions
Biochem Soc Trans (2001) 29 (2): 345–349.
https://doi.org/10.1042/bst0290345
Published: 01 May 2001
... Society 2001 gene expression hydrogen peroxide MAP kinases NADPH oxidase signal transduction MAP kinase, mitogen-activated protein kinase NF-κB, nuclear factor-κB NOH, NADPH oxidase homologue ROS, reactive oxygen species SOD, superoxide dismutase Biochemical and Biomedical Aspects...
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Articles

Toll-like receptors: lessons from knockout mice

S. Akira
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (5): 551–556.
https://doi.org/10.1042/bst0280551
Published: 01 October 2000
... necrosis factor MAP kinase, mitogen-activated protein kinase Innate Immunity Toll-like receptors: lessons from knockout mice S. Akira' Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, CREST of Japan Science and Technology Corporation, 3- I Yamada-oka, Suita...
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Articles

The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defence

L. O'neill
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (5): 557–563.
https://doi.org/10.1042/bst0280557
Published: 01 October 2000
... kinase LPS, lipopolysaccharide NF-κB, nuclear factor-κB TIR, Toll/IL-1 receptor TLR, Toll-like receptor MAP kinase, mitogen-activated protein kinase TRAF6, tumour necrosis factor receptor-associated factor 6 1κB, inhibitory κB IKK 1κB kinase Innate Immunity The Tolllinterleukin- I receptor...
View article titled, The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defence
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Articles

Regulation of GLUTI in response to cellular stress

S. A. Baldwin, L. F. Barros, M. Griffiths, J. Ingram, E. C. Robbins, A. J. Streets, J. Saklatvala
Journal: Biochemical Society Transactions
Biochem Soc Trans (1997) 25 (3): 954–958.
https://doi.org/10.1042/bst0250954
Published: 01 August 1997
... JNK, C-terminal Jun kinase MAP kinase, mitogen-activated protein kinase PI 3-kinase, phosphatidylinositol 3-kinase SAPK, stress-activated protein kinase Biochemical Society Transactions 954 that appears to be technically unfeasible at this time. In the meantime, however, valuable bits and pieces...
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Articles

Multi-site phosphorylation of p53 by protein kinases inducible by p53 and DNA damage

D. W. Meek, L. E. Campbell, L. J. Jardine, U. Knippschild, L. McKendrick, D. M. Milne
Journal: Biochemical Society Transactions
Biochem Soc Trans (1997) 25 (2): 416–419.
https://doi.org/10.1042/bst0250416
Published: 01 May 1997
... it to be tightly regulated in the Abbreviations used: CKl, casein kinase 1; DNA-PK, DNA-activated protein kinase; ERK, extracellular ligand-regulated kinase; JNK, Jun N-terminal kinase; MAP kinase, mitogen-activated protein kinase; SAP kinase, stress-activated protein kinase; p53NK, p53 N-terminus-targeted protein...
View article titled, Multi-site phosphorylation of p53 by protein kinases inducible by p53 and DNA damage
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Articles

Glycogen synthase: activation by insulin and effect of transgenic overexpression in skeletal muscle

J. C. Lawrence, Jr., A. V. Skurat, P. J. Roach, I. Azpiazu, J. Manchester
Journal: Biochemical Society Transactions
Biochem Soc Trans (1997) 25 (1): 14–19.
https://doi.org/10.1042/bst0250014
Published: 01 February 1997
...J. C. Lawrence, Jr.; A. V. Skurat; P. J. Roach; I. Azpiazu; J. Manchester § To whom correspondence should be addressed. 5 8 1996 © 1997 Biochemical Society 1997 PP1 G , glycogen-bound form type-1 protein phosphatase MAP kinase, mitogen-activated protein kinase ISPK...
View article titled, Glycogen synthase: activation by insulin and effect of transgenic overexpression in skeletal muscle
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Articles

Role of protein kinases in nerve terminal maturation and function

E. Valtorta, F. Benfenati, H. Basudev
Journal: Biochemical Society Transactions
Biochem Soc Trans (1996) 24 (3): 645–653.
https://doi.org/10.1042/bst0240645
Published: 01 August 1996
... 2+ ] i , intracellular calcium concentration VAMP, vesicle-associated membrane protein GAP 43, growth-associated membrane protein MARCKS, myristoylated alanine-rich C-kinase substrate FAK, focal adhesion kinase FRNK, FAK-related non-kinase EGF, epidermal growth factor MAP kinase, mitogen...
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Articles

The intracellular reducing environment modulates cytoregulation and cytotoxicity by reactive oxygen species

D. T.-Y. Chiu, H. P. Monteiro, A. Stern
Journal: Biochemical Society Transactions
Biochem Soc Trans (1996) 24 (3): 884–887.
https://doi.org/10.1042/bst0240884
Published: 01 August 1996
... -nitroso- N -acetylpenicillamine MAP kinase, mitogen-activated protein kinase Biochemical Society Transactions 16 17 18 19 20 21 22 23 24 25 Meister, A. and Anderson, M. E. (1983) Annu. Rev. Biochem. 52, 71 1-760 Sics, I . , Akerboom, 7 . and Ishikawa, r. (1989) in Glutathione Centennial (Taniguchi...
View article titled, The intracellular reducing environment modulates cytoregulation and cytotoxicity by reactive oxygen species
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Articles

C-Terminal motifs found in Ras-superfamily G-proteins: CAAX and C-seven motifs

K. Del Villar, D. Dorin, I. Sattler, J. Urano, P. Poullet, N. Robinson, H. Mitsuzawa, F. Tamanoi
Journal: Biochemical Society Transactions
Biochem Soc Trans (1996) 24 (3): 709–713.
https://doi.org/10.1042/bst0240709
Published: 01 August 1996
... Society 1996 CAAL, the same as CAAX except that the C-terminal residue is leucine or phenylalanine CAAX, cysteine followed by two aliphatic amino acids and the C-terminal amino acid X FTase, protein farnesyltransferase GGTase, protein geranylgeranyltransferase MAP kinase, mitogen-activated...
View article titled, C-Terminal motifs found in Ras-superfamily G-proteins: CAAX and C-seven motifs
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Articles

Tyrosine Phosphorylation: Past, Present and Future

T. Hunter
Journal: Biochemical Society Transactions
Biochem Soc Trans (1996) 24 (2): 307–327.
https://doi.org/10.1042/bst0240307
Published: 01 May 1996
...T. Hunter 9 1 1996 © 1996 Biochemical Society 1996 CSF-1, colony-stimulating factor-1 EGF, epidermal growth factor IP 3 , inositol 1,4,5-trisphosphate MAP kinase, mitogen-activated protein kinase NGF, nerve growth factor PDGF, platelet-derived growth factor PH, pleckstrin...
View article titled, Tyrosine Phosphorylation: Past, Present and Future
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Articles

Regulation of insulin gene transcription by nutrients

K. Docherty, W. M. Macfarlane, M. L. Read, S. B. Smith, M. E. Wilson, I. Bujalska, M. Gilligan
Journal: Biochemical Society Transactions
Biochem Soc Trans (1996) 24 (2): 368–372.
https://doi.org/10.1042/bst0240368
Published: 01 May 1996
...K. Docherty; W. M. Macfarlane; M. L. Read; S. B. Smith; M. E. Wilson; I. Bujalska; M. Gilligan * To whom correspondence should be addressed 20 12 1995 © 1996 Biochemical Society 1996 bHLH, basic helix—loop—helix MAP kinase, mitogen-activated protein kinase MEK, MAP kinase...
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Articles

Cyclin from Sea Urchins to HeLas: Making the Human Cell Cycle

Jonathon Pines
Journal: Biochemical Society Transactions
Biochem Soc Trans (1996) 24 (1): 15–33.
https://doi.org/10.1042/bst0240015
Published: 01 February 1996
...Jonathon Pines 22 8 1995 © 1996 Biochemical Society 1996 APC, anaphase promoting complex CDK, cyclin-dependent kinase CAK, CDK-activating kinase CDI, CDK-inhibitor protein MAP kinase, mitogen-activated protein kinase MPF, M-phase promoting factor PKA, protein kinase A Rb...
View article titled, Cyclin from Sea Urchins to HeLas: Making the Human Cell Cycle
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Articles

Interleukin I receptors and signal transduction

L A. J. O'neill
Journal: Biochemical Society Transactions
Biochem Soc Trans (1996) 24 (1): 207–211.
https://doi.org/10.1042/bst0240207
Published: 01 February 1996
...L A. J. O'neill 14 8 1995 © 1996 Biochemical Society 1996 hsp27, heat-shock protein 27 IL, interleukin IL1RA, interleukin 1 receptor antagonist IL1RI/II, Type I and II IL1 receptors MAP kinase, mitogen-activated protein kinase Pharmacological Targets in the Immune Response...
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Articles

Characterisation of a novel “22kDa” phosphoprotein which may be important in insulin action

TRICIA A. DIGGLE, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (2): 209S.
https://doi.org/10.1042/bst023209s
Published: 01 May 1995
...TRICIA A. DIGGLE; RICHARD M. DENTON © 1995 Biochemical Society 1995 IEF, isoelectric focusing eIF-4E, eukaryotic initiation factor-4E PHAS-I, Phosphorylated, Heat and Acid-Stable protein regulated by Insulin BP-1, 2, binding proteins-1 and 2 MAP kinase, mitogen-activated protein kinase...
View article titled, Characterisation of a novel “22kDa” phosphoprotein which may be important in insulin action
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Articles

Molecular mechanisms of regulation of phosphoinositide 3-kinase by insulin, insulin-like growth factor I and nerve growth factor in PC12 cells

A. N. Carter, C. P. Downes
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (1): 148–152.
https://doi.org/10.1042/bst0230148
Published: 01 February 1995
...-derived growth factor EGF, epidermal growth factor IRS-1, insulin receptor substrate 1 PKC, protein kinase C MAP kinase, mitogen-activated protein kinase Biochemical Society Transactions I48 Y., Bell, L,. Saari, G. C., Grant, F. J., O Hara, P. and MacKay, V. (1989) Cell 56,467-477 89 Bauer. P. H...
View article titled, Molecular mechanisms of regulation of phosphoinositide 3-kinase by insulin, insulin-like growth factor I and nerve growth factor in PC12 cells
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Articles

Important roles for novel protein phosphatases dephosphorylating serine and threonine residues

Patricia T. W. Cohen
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (4): 884–888.
https://doi.org/10.1042/bst0210884
Published: 01 November 1993
...Patricia T. W. Cohen 4 8 1993 © 1993 Biochemical Society 1993 PP, protein phosphatase MAP kinase, mitogen-activated protein kinase Biochemical Society Transactions ~ ~~ Important roles for novel protein phosphatases dephosphorylating serine and threonine residues Patricia T...
View article titled, Important roles for novel protein phosphatases dephosphorylating serine and threonine residues
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Articles

Role of p21 ras in growth factor signal transduction

Boudewijn M. Th. Burgering, Gijsbertus J. Pronk, Jan Paul Medema, Loesje van der Voorn, Alida M. M. de Vries Smits, Pascale C. van Weeren, Johannes L. Bos
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (4): 888–894.
https://doi.org/10.1042/bst0210888
Published: 01 November 1993
..., GTPase-activating protein GRF, guanine-nucleotide releasing factor MAP kinase, mitogen-activated protein kinase PDGF, platelet-derived growth factor PKC, protein kinase C PMA, phorbol 12-myristate 13-acetate Biochemical Society Transactions 888 19. Fernandez-Sarahia, M. J., Sutton, A., Zhong, T...
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Articles

Cytoplasmic to nuclear signal transduction by mitogen-activated protein kinase and 90 kDa ribosomal S6 kinase

Rey-Huei Chen, Rosann Tung, Cory Abate, John Blenis
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (4): 895–900.
https://doi.org/10.1042/bst0210895
Published: 01 November 1993
... phosphorylate several nuclear Abbreviations used: MAP kinase, mitogen-activated protein kinase; RSK, 90 kDa ribosomal S6 kinase; SKE, serum response element; SRF, serum response factor. ?To whom correspondence should be addressed. $Present address: Robert Wood Johnson Medical School, CAHM, Piscataway, NJ 08854...
View article titled, Cytoplasmic to nuclear signal transduction by mitogen-activated protein kinase and 90 kDa ribosomal S6 kinase
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Articles

Roles of glycogen synthase kinase-3 in signal transduction

James R. Woodgett, Simon E. Plyte, Bernd J. Pulverer, Jennifer A. Mitchell, Ken Hughes
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (4): 905–907.
https://doi.org/10.1042/bst0210905
Published: 01 November 1993
...James R. Woodgett; Simon E. Plyte; Bernd J. Pulverer; Jennifer A. Mitchell; Ken Hughes 26 7 1993 © 1993 Biochemical Society 1993 GSK-3, glycogen synthase kinase-3 MAP kinase, mitogen-activated protein kinase PKC, protein kinase C Signalling from the Plasma Membrane...
View article titled, Roles of glycogen synthase kinase-3 in signal transduction
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Articles

Signalling to chromatin and the superinduction of proto-oncogenes

Nikolai Zhelev, Efterpi Kardalinou, Catherine A. Hazzalin, Eva Cano, Michael J. Barratt, Louis C. Mahadevan
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (4): 907–912.
https://doi.org/10.1042/bst0210907
Published: 01 November 1993
...-early genes MAP kinase, mitogen-activated protein kinase PMA, phorbol 12-myristate 13-acetate Signalling from the Plasma Membrane to the Nucleus by the activation of a tyrosine phosphatase. In addi- tion, genetic screens for GSK-3 regulators are in progress using a variety of yeast mutants...
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Articles

Dissection of the Protein Phosphorylation Cascades Involved in Insulin and Growth Factor Action

Philip Cohen
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (3): 555–567.
https://doi.org/10.1042/bst0210555
Published: 01 August 1993
..., mitogen-activated protein kinase MAPKK, MAP-kinase kinase MAPKKK, MAP-kinase-kinase kinase NGF, nerve growth factor PC 12, phaechromocytoma PKA, cyclic AMP-dependent protein kinase PP1,2A, protein phosphatase-1,2A PP1G, glycogen-associated PP1 n I D Dissection of the Protein Phosphorylation...
View article titled, Dissection of the Protein Phosphorylation Cascades Involved in Insulin and Growth Factor Action
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Articles

Insulin-activated protein kinases in fat and other cells

Richard M. Denton, Jeremy M. Tavaré, Andrew Borthwick, Martin Dickens, Tricia A. Diggle, Nigel J. Edged, Kate J. Heesom, Tarik Isaad, Deborah F. Lynch, S. Kelly Moule, Carsten Schmitz-Peiffer, Gavin I. Welsh
Journal: Biochemical Society Transactions
Biochem Soc Trans (1992) 20 (3): 659–664.
https://doi.org/10.1042/bst0200659
Published: 01 August 1992
...Richard M. Denton; Jeremy M. Tavaré; Andrew Borthwick; Martin Dickens; Tricia A. Diggle; Nigel J. Edged; Kate J. Heesom; Tarik Isaad; Deborah F. Lynch; S. Kelly Moule; Carsten Schmitz-Peiffer; Gavin I. Welsh CHO, Chinese hamster ovary MAP kinase, mitogen-activated protein kinase © 1992...
View article titled, Insulin-activated protein kinases in fat and other cells
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Articles

Apparent sufficiency of a dual-specificity tyrosine/threonine kinase for activation of MAP kinase poses new questions for the dual-phosphorylation mechanism

Jie Wu, Anthony J. Rossomando, Jeng Horng-Her, Michael J. Weber, Thomas W. Sturgill
Journal: Biochemical Society Transactions
Biochem Soc Trans (1992) 20 (3): 675–677.
https://doi.org/10.1042/bst0200675
Published: 01 August 1992
...Jie Wu; Anthony J. Rossomando; Jeng Horng-Her; Michael J. Weber; Thomas W. Sturgill 9 4 1992 © 1992 Biochemical Society 1992 C, catalytic subuit of cAMP-dependent protein kinase MAP kinase, mitogen-activated protein kinase MAPKK, MAP kinase kinase Gene Expression Control...
View article titled, Apparent sufficiency of a dual-specificity tyrosine/threonine kinase for activation of MAP kinase poses new questions for the dual-phosphorylation mechanism
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Articles

Rapid activation of MAP kinase and S6 kinase by growth hormone in 3T3-F442A preadipocytes

NEIL G. ANDERSON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1992) 20 (3): 270S.
https://doi.org/10.1042/bst020270s
Published: 01 August 1992
...NEIL G. ANDERSON © 1992 Biochemical Society 1992 GH, growth hormone DMEM, Culbecco's modification of Eagle's medium MAP kinase, mitogen-activated protein kinase 642nd Meeting Southampton: 642nd Meeting held at the University of Southampton 7–10 April 1992 270s Biochemical...
View article titled, Rapid activation of MAP kinase and S6 kinase by growth hormone in 3T3-F442A preadipocytes
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