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Keywords: M1 ubiquitination
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Biochem Soc Trans (2021) 49 (5): 2443–2454.
Published: 28 October 2021
... there is a catalytic role for HOIL-1L in M1 ubiquitination. While the answer is not completely established, based on recent studies, the following functions of the ligase are starting to emerge: (1) Attaching the first ubiquitin prior to M1-linked chain formation : In in vitro ubiquitination assays, HOIP‘s...