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Keywords: KMT2
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 427–434.
Published: 25 January 2023
...Zi Yang; Robert Zepeda; Yali Dou The MLL/KMT2 family enzymes are frequently mutated in human cancers and congenital diseases. They deposit the majority of histone 3 lysine 4 (H3K4) mono-, di-, or tri-methylation in mammals and are tightly associated with gene activation. Structural and biochemical...