... cartilage degradation elF2-α osteoarthritis TNF-α PKR, protein kinase R PACT, protein kinase R-activating protein OA, osteoarthritis elF2-α, eukaryotic initiation factor 2-α TNF-α, tumour necrosis factor α IL-1, interleukin-1 RA, rheumatoid arthritis NF-κB, nuclear factor κB 1KK, inhibitory...

...-mail laoneill@tcd.ie 21 7 2000 © 2000 Biochemical Society 2000 MAP kinase MyD88 NF-κB Toll-like receptor IL-1, interleukin-1 IL-IRAcP, IL-1 receptor accessory protein IL-IRI, Type-I IL-1 receptor IRAK, IL-1 receptor-associated kinase IL-18R, IL-18 receptor JNK, Jun N-terminal...

...NICOLA T. NEVILLE; SIMON K. JACKSON; JOHN L. HARWOOD © 1997 Biochemical Society 1997 IFN γ, interferon-gamma PC, phosphatidylcholine IL-1, interleukin-1 PE, phosphatidylethanolamine PI, phosphatidylinositol TNFα, tumour necrosis factor alpha 661st Meeting Bath: 661st Meeting...

...CLARE M. MORLAND; JANINE FEAR; RUTH JOPLIN; DAVID H. ADAMS © 1997 Biochemical Society 1997 IL-8, interleukin-8 MCP-1, monocyte chemotactic protein-1 BEC, biliary epithilial cell TNF, tumour necrosis factor IL-1, interleukin-1 IFN, interferon TGF, transforming growth factor RT-PCR...

...KATHERINE FITZGERALD; LUKE A.J. O'NEILL © 1997 Biochemical Society 1997 IL-1, interleukin-1 IL-1 RA, interleukin-1 receptor antagonist PMA, phorbol 12-meristate 13-acetate TNF, tumour necrosis factor HRP, horse radish peroxidase 660th Meeting Harrogate: 660th Meeting Joint...

...D. D. Rees 28 7 1995 © 1995 Biochemical Society 1995 IFN- y , interferon- y IL-1, interleukin-1 IL-6, interleukin-6 l-NMMA, N G -monomethyl-L-arginine TNF-α, tumour necrosis factor-α Endotoxic Shock and Metabolism 41 Buse, M. G. and Reid, S. S. (1975) J. Clin. Invest...

.... and Salzman, E. W. (1984) Blood 63,848-857 16 Klausner, R. D., Bhalla, D. K., Dragsten, I Hoover. R. L. and Karnovsky. M. J. ( 1 980) Proc. Natl. Acad. Sci. USA. 77,437-44 1 Received 14 December 1994 Volume 23 LPS, lipopolysaccharide IL-1, interleukin-1 PGE 2 , prostaglandin E 2 TNF-α, tumour necrosis...

... NO, nitric oxide [Ca 2+ ] i , free calcium ion concentration IL-1, interleukin-1 Insulin Secretion and B-Cell Dysfunction 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. Tsuura, Y., Ishida, H., Okamoto, Y., Kato, S., Sakamoto, K., Horie, M., Ikeda, H., Okada, Y. and Seino, Y. (1992) Diabetes 42...

...–6 April 1990 OA, osteoarthritis PG, proteoglycans IL-1, interleukin-1 TNFα, tumour necrosis factor α IGF-1, insulin-like growth factor TGFβ, transforming growth factor β DMEM, Dulbecco's modified Eagle's medium GAG, glycosaminoglycan © 1990 Biochemical Society 1990 7 3...

...PAUL A. GLAZER; WALID AZZO; FATEMEH SAED-NEJAD; ANTHONY RATCLIFFE 6 3 1990 © 1990 Biochemical Society 1990 IL-1, interleukin-1 MMP, matrix metalloproteinase NSAID, non-steroidal anti-inflammatory drug TIMP, tissue inhibitor of metalloproteinases 634th Meeting Bath...

...DAVID J. TAYLOR 5 3 1990 © 1990 Biochemical Society 1990 RSC, rheumatoid synovial cells IL-1, interleukin-1 HDF, human dermal fibroblasts FAP, familial adenopolyposis DMEM, Dublecco's modified Eagle's medium FCS, fetal calf serum Fru(2,6) P 2 , fructose 2,6-bisphosphate...

...J. WATSON; R. MADHOK; E. WIJELATH; H. A. CAPELL; J. GILLESPIE; J. SMITH; M. L. BYARS 15 9 1989 © 1990 Biochemical Society 1990 IL-1, interleukin-1 RA, rheumatoid arthritis LPS, lipopolysaccharide 632nd Meeting Cork: 632nd Meeting Held at University College Cork, 19–22...

...L. A. J. O'NEILL; G. P. LEWIS 13 4 1988 © 1988 Biochemical Society 1988 IL-1, interleukin-1 PGE 2 , prostaglandin E 2 NSAID, non-steroidal anti-inflammatory drug 626th Meeting Sheffield: 626th Meeting Held at the University of Sheffield, 13–15 April 1988 892...

...YOUSEF S. TAKTAK; ANDREW M. GRANT 27 11 1986 © 1987 Biochemical Society 1987 IL-1, interleukin-1 621st Meeting Held at University College, London: 621st Meeting Held at University College, London, on 17–19 December 1986 621st MEETING, LONDON 67 1 Hutchinson, W. L...