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Keywords: HD-PTP
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Biochem Soc Trans (2018) 46 (5): 1037–1046.
Published: 06 September 2018
.... Here, we review the yeast ESCRT pathway and describe the corresponding components in mammalian cells that sort EGFR. One of these is His domain protein tyrosine phosphatase (HD-PTP/PTPN23), and we review the interactions involving HD-PTP and ESCRTs. Finally, we describe a working model for how...
Biochem Soc Trans (2017) 45 (3): 845–854.
Published: 15 June 2017
.... The ESCRT member HD-PTP/ PTPN23 was recently identified as a novel haplo-insufficient tumour suppressor in vitro and in vivo , in mice and humans. In this mini-review, we outline the role of the ESCRT components in cancer and summarize the functions of HD-PTP/ PTPN23 in tumorigenesis. Correspondence...