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Keywords: Gag
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Biochem Soc Trans (2010) 38 (6): 1548–1552.
Published: 24 November 2010
... is that ribosomal recruitment relies, at least in part, on IRES structural determinants. Lentiviral genomic RNAs present an additional level of complexity, as, in addition to the 5′-UTR (untranslated region) IRES, the presence of a new type of IRES, embedded within Gag coding region was described recently...
Biochem Soc Trans (2008) 36 (4): 690–693.
Published: 22 July 2008
...′-untranslated region), which harbours structural RNA motifs for the replication cycle of the virus. Recent work has shown that this RNA architecture also functions as an IRES (internal ribosome entry site) in HIV-1 and -2, and in SIV (simian immunodeficiency virus). In addition, the IRES extends to the gag...