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Keywords: GTPase-activating proteinClose
Journal: Biochemical Society Transactions
Biochem Soc Trans (2003) 31 (5): 966–969.
Published: 01 October 2003
.... Whether Ras is in its active GTP-bound, or inactive GDP-bound, form is determined by the activity of guanine nucleotide exchange factors (GEFs) and GTPase-activating protein (GAPs). Calcium-regulated GEFs and GAPs have been identified, some with an exquisite sensitivity to [Ca 2+ ] i , implicating...