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Keywords: ESCRT
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Biochem Soc Trans (2019) 47 (1): 441–448.
Published: 19 February 2019
...Christophe Caillat; Sourav Maity; Nolwenn Miguet; Wouter H. Roos; Winfried Weissenhorn The endosomal sorting complex required for transport-III (ESCRT-III) and VPS4 catalyze a variety of membrane-remodeling processes in eukaryotes and archaea. Common to these processes is the dynamic recruitment...
Biochem Soc Trans (2018) 46 (5): 1037–1046.
Published: 06 September 2018
... face of the endosome and generates vesicles that bud into the endosome lumen, but somehow escapes encapsulation itself. This machinery is termed the ESCRT (endosomal sorting complexes required for transport) pathway, a series of multi-protein complexes and accessory factors first identified in yeast...
Biochem Soc Trans (2018) 46 (4): 877–889.
Published: 19 July 2018
... in NPC assembly before INM–ONM fusion. Poly-A (AAA) RNA has been found in herniations as has K48-linked ubiquitin. ( C ) Model of herniation formation due to NPC assembly surveillance by the ESCRT complex (green) and the AAA ATPase Vps4 (pink) recruited by Heh1/LEM2. ( D ) Model of herniation formation...
Biochem Soc Trans (2018) 46 (3): 537–545.
Published: 17 April 2018
...Marisa S. Otegui The degradation of plasma membrane and other membrane-associated proteins require their sorting at endosomes for delivery to the vacuole. Through the endocytic pathway, ubiquitinated membrane proteins (cargo) are delivered to endosomes where the ESCRT (endosomal sorting complex...
Biochem Soc Trans (2017) 45 (3): 845–854.
Published: 15 June 2017
... downstream signalling and tumorigenesis. Since the E ndosomal S orting C omplexes R equired for T ransport (ESCRT) controls these processes, ESCRT components were proposed to act as tumour suppressor genes. However, the bona fide role of ESCRT components in tumorigenesis has not been clearly demonstrated...
Biochem Soc Trans (2017) 45 (3): 613–634.
Published: 15 June 2017
...Edward J. Scourfield; Juan Martin-Serrano The vast expansion in recent years of the cellular processes promoted by the endosomal sorting complex required for transport (ESCRT) machinery has reinforced its identity as a modular system that uses multiple adaptors to recruit the core membrane...