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Keywords: Drosophila melanogaster
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Biochem Soc Trans (2021) 49 (3): 1233–1240.
Published: 07 May 2021
... formation, and investigations using the embryo of the fruit fly Drosophila melanogaster have been crucial in elucidating their dynamics. However, a full understanding of how these components interact has been hampered by the total absence of centrioles in null mutant backgrounds for any of these core...
Biochem Soc Trans (2020) 48 (5): 2101–2115.
Published: 08 September 2020
... division to drive neurogenesis and brain development. Many of the genes, pathways, and developmental paradigms that dictate NSC development in humans are conserved in Drosophila melanogaster . As such, studies of Drosophila NSCs lend invaluable insights into centrosome function within NSCs and help inform...
Includes: Supplementary data
Biochem Soc Trans (2019) 47 (2): 691–700.
Published: 22 March 2019
... to determine a complete picture of the different forms of chromatin present within a cell. In the fruit fly, Drosophila melanogaster , the study of chromatin states has been aided by the use of complementary and cell-type-specific techniques that profile the marks that recruit chromatin protein binding...
Biochem Soc Trans (2017) 45 (4): 895–904.
Published: 03 July 2017
...Oliver M. Rogoyski; Jose Ignacio Pueyo; Juan Pablo Couso; Sarah F. Newbury Genomic analysis has found that the transcriptome in both humans and Drosophila melanogaster features large numbers of long non-coding RNA transcripts (lncRNAs). This recently discovered class of RNAs regulates gene...
Biochem Soc Trans (2016) 44 (5): 1465–1473.
Published: 19 October 2016
... these studies. © 2016 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2016 BMP signalling Drosophila melanogaster extracellular matrix integrins Smad Figure 2. Integrin signalling enhances BMP responses. ( A ) Cartoon showing ligand-dependent...
Biochem Soc Trans (2016) 44 (5): 1549–1560.
Published: 19 October 2016
... ]; therefore, this mini review will focus on the HF mechanisms associated with mechanical forces and how a simple in vivo model, such as fruit fly ( Drosophila melanogaster ), may aid the studies using an empirical data-based in silico approach. Blood flow by exerting haemodynamic force helps...
Biochem Soc Trans (2008) 36 (6): 1313–1316.
Published: 19 November 2008
...Anuja Mehta; Abhyuday Deshpande; Fanis Missirlis Ferritin, a symmetrical 24-subunit heteropolymer composed of heavy and light chains, is the primary iron-storage molecule in bacteria, plants and animals. We used a genetically engineered strain of the model organism Drosophila melanogaster which...
Biochem Soc Trans (2008) 36 (6): 1389–1392.
Published: 19 November 2008
... for the cellular abnormalities seen in HGPS, the mechanism linking progerin to the organismal phenotype is not fully understood. To begin to address the mechanism behind HGPS using Drosophila melanogaster , we have ectopically expressed progerin and lamin A. We found that ectopic progerin and lamin A phenocopy...
Biochem Soc Trans (2006) 34 (6): 1252–1255.
Published: 25 October 2006
... species in biomedical research. Furthermore, insects have evolved sociality several times. The first insect genome was that of the fruitfly Drosophila melanogaster with 85 CYP (cytochrome P450) genes and five pseudogenes [ 1 ] ( http://P450.antibes.inra.fr ). The number of fully sequenced insect genomes...
Biochem Soc Trans (2005) 33 (5): 957–961.
Published: 26 October 2005
... were first uncovered in the fruit fly Drosophila melanogaster , whereas cockroaches were among the first animals where the brain master clock was localized. Despite many similarities, there exist obvious differences in the organization and functioning of insect master clocks. These similarities...
Biochem Soc Trans (2002) 30 (6): 1064–1070.
Published: 01 November 2002
... should be addressed at Wellcome Trust Biocentre, Dundee University, Dow Street, Dundee DDI 5EH, U.K. (e-mail: d.g.hardie@dundee.ac.uk ) 18 7 2002 © 2002 Biochemical Society 2002 acetyl-CoA carboxylase Drosophila melanogaster energy charge HMG-CoA reductase malonyl-CoA ACC...
Biochem Soc Trans (2000) 28 (4): 460–464.
Published: 01 August 2000
... and of circulating peptide hormones in insects and nematodes. A family of neprilysin-like genes are present in the genomes of both Drosophila melanogaster and Caenorhabditis elegans ; in C. elegans it seems that individual family members have evolved to take on different physiological functions, because...