...-resolution fluorescence microscope. 1 To whom correspondence should be addressed (email mark.leake@york.ac.uk ). 19 9 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 DNA topology localization microscopy millisecond microscopy multidimensional microscopy...

.... 1 email Sean.Colloms@glasgow.ac.uk 16 11 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 catenane DNA topology knot site-specific recombination tyrosine recombinase Xer Site-specific recombination performs a wide range of biological...

...Ksenia Terekhova; John F. Marko; Alfonso Mondragón Topoisomerases are the enzymes responsible for maintaining the supercoiled state of DNA in the cell and also for many other DNA-topology-associated reactions. Type IA enzymes alter DNA topology by breaking one DNA strand and passing another strand...

...@math.usask.ca or michael.szafron@usask.ca ). 12 11 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 crossing-sign discrimination DNA topology knot-reduction self-avoiding polygon strand-passage model type II topoisomerase Type II topoisomerases are enzymes...

...Jorge B. Schvartzman; María-Luisa Martínez-Robles; Pablo Hernández; Dora B. Krimer DNA topology changes dynamically during DNA replication. Supercoiling, precatenation, catenation and knotting interplay throughout the process that is finely regulated by DNA topoisomerases. In the present article...

... (nucleosome assembly protein 1), only H3–H4 dimers are obtained, which induce positively supercoiled DNA [ 18 ]. Thus DNA topology might be modulated by conformational changes in the H3–H4 complex through variation of NAP1 activity/concentration. Although such a transition has never been observed...

... induced by alkylating agent in the archaeon Sulfolobus solfataricus Nucleic Acids Res. 2006 34 2098 2108 archaeon DNA topology genome stability helicase hyperthermophile topoisomerase DNA topoisomerases are essential enzymes that regulate the topological state of DNA in all...

...A.J. Schoeffler; J.M. Berger DNA topos (topoisomerases) are complex, multisubunit enzymes that remodel DNA topology. Members of the type II topo family function by passing one segment of duplex DNA through a transient break in another, a process that consumes two molecules of ATP and requires...