..., core maturation and reverse transcription [ 5 – 9 , 86 , 87 , 130 – 132 ]. 6 4 2016 8 8 2016 17 8 2016 © 2016 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2016 DNA polymerase retrovirus RNA chaperones In the interior...

...Joshua P. Gill; Jun Wang; David P. Millar DNA polymerases are essential enzymes responsible for replication and repair of DNA in all organisms. To replicate DNA with high fidelity, DNA polymerases must select the correct incoming nucleotide substrate during each cycle of nucleotide incorporation...

... The Authors Journal compilation © 2010 Biochemical Society 2010 anaphase-promoting complex (APC) DNA damage DNA polymerase proliferating-cell nuclear antigen (PCNA) translesion synthesis ubiquitination Transmission of genetic materials from one generation to the next is the essence of life...

...Bernard A. Connolly Archaeal family-B DNA polymerases interact specifically with uracil and hypoxanthine, stalling replication on encountering these deaminated bases in DNA template strands. The present review describes X-ray structural data which elucidate the mechanism of read-ahead recognition...

... enzyme, has a novel domain, termed prim/pol domain. This domain constitutes the first member of the DNA polymerase family E. Based on the biochemical characterization of the gene products a model of how pRN1 is replicated in vivo is proposed. 1 e-mail georg.lipps@uni-bayreuth.de Thermophiles...

...B.A. Connolly; M.J. Fogg; G. Shuttleworth; B.T. Wilson Archaeal family-B DNA polymerases possess a novel uracil-sensing mechanism. A specialized pocket scans the template, ahead of the replication fork, for the presence of uracil; on encountering this base, DNA synthesis is stalled. The structural...