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Keywords: DNA polymerase
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Biochem Soc Trans (2016) 44 (5): 1427–1440.
Published: 19 October 2016
... 2016 17 8 2016 © 2016 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2016 DNA polymerase retrovirus RNA chaperones Retroviruses constitute a large family of small enveloped plus-strand RNA viruses ( Figure 1A ) that are widespread...
Biochem Soc Trans (2011) 39 (2): 595–599.
Published: 22 March 2011
...Joshua P. Gill; Jun Wang; David P. Millar DNA polymerases are essential enzymes responsible for replication and repair of DNA in all organisms. To replicate DNA with high fidelity, DNA polymerases must select the correct incoming nucleotide substrate during each cycle of nucleotide incorporation...
Biochem Soc Trans (2010) 38 (1): 110–115.
Published: 19 January 2010
...-family polymerases. Like high-fidelity replicative polymerases, Y-family DNA polymerases contain the typical catalytic core, including thumb, fingers and palm domains, in the central region of the proteins. Structural studies of TLS DNA polymerases, however, reveal that the thumb and finger domains...
Biochem Soc Trans (2009) 37 (1): 65–68.
Published: 20 January 2009
...Bernard A. Connolly Archaeal family-B DNA polymerases interact specifically with uracil and hypoxanthine, stalling replication on encountering these deaminated bases in DNA template strands. The present review describes X-ray structural data which elucidate the mechanism of read-ahead recognition...
Biochem Soc Trans (2004) 32 (2): 240–244.
Published: 01 April 2004
... enzyme, has a novel domain, termed prim/pol domain. This domain constitutes the first member of the DNA polymerase family E. Based on the biochemical characterization of the gene products a model of how pRN1 is replicated in vivo is proposed. 1 e-mail georg.lipps@uni-bayreuth.de Thermophiles...
Biochem Soc Trans (2003) 31 (3): 699–702.
Published: 01 June 2003
...B.A. Connolly; M.J. Fogg; G. Shuttleworth; B.T. Wilson Archaeal family-B DNA polymerases possess a novel uracil-sensing mechanism. A specialized pocket scans the template, ahead of the replication fork, for the presence of uracil; on encountering this base, DNA synthesis is stalled. The structural...