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Keywords: Crabtree effect
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Biochem Soc Trans (2013) 41 (1): 124–126.
Published: 29 January 2013
...Emily K. Redman; Paul S. Brookes; Marcin K. Karcz High glucose inhibits mitochondrial respiration, known as the ‘Crabtree effect’, in cancer cells and possibly other cell types. The upstream pathways regulating this phenomenon are poorly understood. In diabetes, where glucose levels are elevated...