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Keywords: CpG islands
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Biochem Soc Trans (2021) 49 (3): 1109–1119.
Published: 22 June 2021
... are CpG-rich DNA sequences called CpG islands (CGIs), which are mostly hypomethylated relative to the bulk genome. CGIs overlap promoters from the earliest vertebrates to humans, indicating a concerted evolutionary drive compatible with CGI retention. CGIs are characterised by DNA sequence features...