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Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (1): 15–23.
Published: 10 January 2020
...Claudio Hidalgo-Cantabrana; Rodolphe Barrangou CRISPR-Cas constitutes the adaptive immune system of bacteria and archaea. This RNA-mediated sequence-specific recognition and targeting machinery has been used broadly for diverse applications in a wide range of organisms across the tree of life...