... © The Authors Journal compilation © 2014 Biochemical Society 2014 Candida albicans Cdc42 filamentous growth G-protein phospholipid Saccharomyces cerevisiae A number of fungi can grow by asexual reproduction via budding growth, in which a small bud is formed on a mother cell...

...T.C. White; P.M. Silver Candida albicans is an important pathogenic fungus of humans, causing a range of infections. These infections are usually treated with antifungal drugs that target sterol metabolism. Resistance to these antifungals can result from overexpression of sterol biosynthetic genes...

...R. Pasrija; T. Prasad; R. Prasad By exploiting the biosynthetic pathways of raft lipid constituents, in this study we demonstrate that fluctuations in either sphingolipid or ergosterol levels result in increased drug sensitivity and morphological defects in Candida albicans cells. We show that any...

...M.M. Maidan; J.M. Thevelein; P. Van Dijck Yeast-to-hypha transition in Candida albicans can be induced by a wide variety of factors, including specific nutrients. We have started to investigate the mechanism by which some of these nutrients may be sensed. The G-protein-coupled receptor Gpr1...

... obtained with mammalian cells. However, very little is known about the roles played by these lipids in plants and fungi. To initiate such investigations we have cloned and characterized a ceramide glucosyltransferase from the yeast Candida albicans. Functional expression of this gene in Saccharomyces...