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Keywords: CD95
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Biochem Soc Trans (2004) 32 (5): 679–681.
Published: 26 October 2004
... debate. Our data suggest that neutrophil apoptosis involves a novel mechanism of caspase 8 activation that is indirectly regulated by accumulation of reactive oxygen species. We detected early activation of caspase 8 upstream of caspase 3 activation, suggesting death receptor signalling. The CD95 DISC...