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Keywords: CD8
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Biochem Soc Trans (2015) 43 (4): 734–739.
Published: 03 August 2015
... of rapamycin (mTOR) to be a key modulator of aging and the use of mTOR inhibitors has been shown to ameliorate much age-related pathology; however, recent data suggest that senescent CD8 + T-cells function independently of mTOR. This review article will challenge the perceived dogma that mTOR universally...
Biochem Soc Trans (2008) 36 (3): 316–320.
Published: 21 May 2008
...F. Susan Wong; L. Khai Siew; Li Wen The autoimmune attack on pancreatic β-cells is orchestrated by a variety of cells that produce cytokines and other toxic mediators. CD8 + T-cells work together with other lymphocytes and antigen-presenting cells to mediate this damage and have been shown...