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Keywords: Barrett's metaplasia
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Articles
Biochem Soc Trans (2010) 38 (2): 364–369.
Published: 22 March 2010
... of the transcription factors that specify tissue identity during normal embryonic development. Barrett's metaplasia describes the development of a columnar/intestinal phenotype in the squamous oesophageal epithelium and is the major risk factor for oesophageal adenocarcinoma. This particular type of cancer has...
Articles
Biochem Soc Trans (2010) 38 (2): 348–352.
Published: 22 March 2010
... of squamous cells or through Barrett's metaplasia. The prevailing concept of reflux oesophagitis pathogenesis is essentially a chemical burn model of injury. It is assumed that refluxed gastric acid and pepsin cause caustic cell injury and cell death, with progression from the luminal surface...
Articles
Biochem Soc Trans (2010) 38 (2): 337–342.
Published: 22 March 2010
...James Cronin; Lisa Williams; Elizabeth McAdam; Zak Eltahir; Paul Griffiths; John Baxter; Gareth Jenkins Bile acids have been demonstrated, through the use of animal models and clinical association studies, to play a role in neoplastic development in Barrett's metaplasia. How specific bile acids...