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Keywords: BMP
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Articles
Biochem Soc Trans (2022) 50 (2): 703–712.
Published: 14 March 2022
... tissues ranging from proliferation, cell death and differentiation to lineage determination, organ morphogenesis and tissue homeostasis [ 5 , 7 , 8 ]. The family comprises over 30 members, including TGFβ1–3, Activins, Bone Morphogenetic Proteins (BMPs) and Growth and Differentiation Factors (GDFs) [ 9...
Articles
Biochem Soc Trans (2020) 48 (2): 411–418.
Published: 13 March 2020
...Sylvain Lefort; Véronique Maguer-Satta The bone morphogenetic protein (BMP) pathway regulates the fate and proliferation of normal hematopoietic stem cells (HSC) as well as interactions with their niche. While BMP2 and BMP4 promote HSC differentiation, only BMP4 maintains HSC pool and favors...
Articles
Biochem Soc Trans (2019) 47 (5): 1471–1479.
Published: 24 September 2019
... [ 67 ], medulloblastoma [ 68 ], craniapharyngioma [ 69 ], midbrain glioma [ 66 ] and pilocytic astrocytoma [ 70 ]. ACVR1 encodes for the transmembrane type I bone morphogenetic protein (BMP) receptor ALK2, which displays an extracellular ligand-binding domain and an intracellular serine...