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Keywords: Alzheimer's disease (AD)
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Articles
Biochem Soc Trans (2012) 40 (4): 711–715.
Published: 20 July 2012
... not follow either Braak Lewy body staging [ 12 ] or McKeith criteria [ 13 ]). Alzheimer's disease (AD) Braak stages brainstem neuropathology subcortical tau pathology The Biology and Pathology of Tau and its Role in Tauopathies II: A Biochemical Society Focused Meeting held at Robinson...
Articles
Biochem Soc Trans (2011) 39 (4): 898–901.
Published: 20 July 2011
... Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) central nervous system (CNS) microglial cell systemic inflammation In humans, evidence of communication between systemic inflammation and the CNS (central nervous system) is visible...
Articles
Biochem Soc Trans (2011) 39 (4): 891–897.
Published: 20 July 2011
... ]. This clearly limits the application of BDNF as a treatment for AD. Alzheimer's disease (AD) central nervous system (CNS) glucagon-like peptide-1 (GLP1) insulin receptor substrate (IRS) Type 2 diabetes mellitus (T2DM) AD (Alzheimer's disease) is a progressive neurodegenerative disease for which...
Articles
Biochem Soc Trans (2011) 39 (4): 868–873.
Published: 20 July 2011
...- and oxidative stress-induced cell death. These animals also exhibited significantly improved learning and memory functions in comparison with transgenic mAPP mice with normal expression of CypD [ 25 ]. Alzheimer's disease (AD) amyloid-binding alcohol dehydrogenase (ABAD) cyclohexenyl amine naphthalene...
Articles
Biochem Soc Trans (2011) 39 (4): 874–880.
Published: 20 July 2011
... correspondence should be addressed (email b.platt@abdn.ac.uk ). 16 3 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) imaging positron-emission tomography (PET) power spectrum quantitative electroencephalogram sleep Translational...
Articles
Biochem Soc Trans (2011) 39 (4): 902–909.
Published: 20 July 2011
... Alzheimer's disease (AD) amyloid β-peptide (Aβ) dentate gyrus (DG) episodic-like memory hippocampal synaptic activity pattern separation There is converging evidence from both human and animal studies that the initial stages of AD (Alzheimer's disease) are associated with synaptic pathology...
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Articles
Biochem Soc Trans (2011) 39 (4): 924–932.
Published: 20 July 2011
... detrimental effects. 1 email yhuang@gladstone.ucsf.edu 27 2 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) animal model apolipoprotein E (apoE) cognitive impairment neurodegeneration ApoE, a 299-amino-acid...
Articles
Biochem Soc Trans (2011) 39 (4): 881–885.
Published: 20 July 2011
... The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) axon–glial integrity hypoperfusion vascular disease white matter The integrity of the white matter is critical in regulating efficient neuronal communication and maintaining...
Articles
Biochem Soc Trans (2011) 39 (4): 939–944.
Published: 20 July 2011
... ). 6 12 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) arterial hypertension lipopolysaccharide murine model AD is the leading cause of dementia in the elderly and, although some treatments help...
Articles
Biochem Soc Trans (2011) 39 (4): 945–953.
Published: 20 July 2011
... inflammation is a major contributor to the progression of dementia and constitutes an important clinical target. 1 email colm.cunningham@tcd.ie 19 1 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) animal model delirium dementia...
Articles
Biochem Soc Trans (2011) 39 (4): 857–861.
Published: 20 July 2011
... compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) amyloid precursor protein (APP) human pathology intraneuronal amyloid β-peptide (intraneuronal Aβ) neuron loss AD (Alzheimer's disease) represents the most frequent form of dementia...
Articles
Biochem Soc Trans (2010) 38 (1): 150–155.
Published: 19 January 2010
... or aggresome. © The Authors Journal compilation © 2010 Biochemical Society 2010 aggresome Alzheimer's disease (AD) presenilin proteasome protein aggregation ubiquilin-1 Ubiquilin-1 [also known as PLIC-1 (protein linking IAP (integrin-associated protein) with cytoskeleton-1)] belongs...
Articles
Biochem Soc Trans (2005) 33 (5): 1096–1100.
Published: 26 October 2005
... The Biochemical Society 2005 Alzheimer's disease (AD) amyloid precursor protein (APP) β-site amyloid precursor protein-cleaving enzyme (BACE) cholesterol platelet post-mortem brain protease Proteins in Disease: A Focus Topic at BioScience2005, held at SECC Glasgow, U.K., 17–21 July 2005...
Articles
Biochem Soc Trans (2005) 33 (5): 1033–1036.
Published: 26 October 2005
... resistance. 1 To whom correspondence should be addressed (email tjnelson@brni-jhu.org ). 17 6 2005 © 2005 The Biochemical Society 2005 Alzheimer's disease (AD) β-amyloid cholesterol insulin memory protein kinase C (PKC) Both insulin and cholesterol have long been...
Articles
Biochem Soc Trans (2005) 33 (5): 1116–1118.
Published: 26 October 2005
... disease (AD) amyloid precursor protein (APP) BACE1 (β-secretase 1) fibrillogenesis glycosaminoglycan (GAG) heparan sulphate (HS) AD is characterized by amyloid brain deposits of Aβ (amyloid β-peptide), formed by the cleavage of APP (amyloid precursor protein) APP by β- and γ-secretase. γ...
Articles
Biochem Soc Trans (1998) 26 (3): S245.
Published: 01 August 1998
...Sarah L. Houldsworth; Alison J. Trew; Nigel M. Hooper; Anthony J. Turner © 1998 Biochemical Society 1998 Alzheimer's disease (AD) β-amyloid protein (βA4) β-amyloid precursor protein (β-APP) angiotensin converting enzyme (ACE) Hip, hippuryl 665th Meeting Southampton: 665th...
Articles
Biochem Soc Trans (1993) 21 (1): 18S.
Published: 01 February 1993
...RUTH M. DUBERLEY; CAROLE R. RICKARDS; JACK HAM; MAURICE F. SCANLON © 1993 Biochemical Society 1993 Alzheimer's Disease (AD) N-methyl-D-aspartate (NMDA) Kainic acid (KA) Quisqualate (Q) Choline acetyltransferase (CHAT) muscarinic acetylcholine receptor (mAchr) inositol monophosphate...