... multidrug ABC transporter ABCB1 is an example of this architecture, and has all four domains fused into a single polypeptide [ 5 ]. ATP-binding cassette transporter (ABC transporter) drug resistance membrane multidrug export © The Authors Journal compilation © 2011 Biochemical Society 2011...

... and transporters found in eukaryotes [ 4 , 5 ]. To date, there is a severe lack of information available on the folding and assembly of oligomeric membrane proteins. © The Authors Journal compilation © 2011 Biochemical Society 2011 ATP-binding cassette transporter (ABC transporter) folding membrane...

... medium, provided the original work is properly cited. ATP-binding cassette transporter (ABC transporter) DNA sliding gyrase heat-shock protein 90 histidine kinase and MutL ATPase (GHKL ATPase) helicase molecular switch Many cellular transactions require enzymes that bind and hydrolyse...

... for future drug design in relation to modulating the action of human ABC transporters. ATP-binding cassette transporter (ABC transporter) ATP-hydrolysis haemolysin B (HlyB) nucleotide-binding domain substrate-assisted catalysis X-ray structure The isolated NBD of HlyB was studied in detail...

... and structural features. Some of these similarities and their implications for the mechanism of transport by ABC multidrug transporters will be discussed. 28 6 2005 © 2005 The Biochemical Society 2005 ATP-binding cassette transporter (ABC transporter) carboxylate LmrA multidrug resistance...