...Giancarlo Solaini; Gianluca Sgarbi; Alessandra Baracca In the last two decades, IF 1 , the endogenous inhibitor of the mitochondrial F 1 F o -ATPase (ATP synthase) has assumed greater and ever greater interest since it has been found to be overexpressed in many cancers. At present, several findings...

...Gabriele Deckers-Hebestreit The ATP synthase (F o F 1 ) of Escherichia coli couples the translocation of protons across the cytoplasmic membrane by F o to ATP synthesis or hydrolysis in F 1 . Whereas good knowledge of the nanostructure and the rotary mechanism of the ATP synthase is at hand...

...John E. Walker The ATP synthases are multiprotein complexes found in the energy-transducing membranes of bacteria, chloroplasts and mitochondria. They employ a transmembrane protonmotive force, Δ p , as a source of energy to drive a mechanical rotary mechanism that leads to the chemical synthesis...

...-containing methanogens have additional coupling sites that also translocate protons. The ATP synthase in this group is promiscuous and uses Na + and H + simultaneously. 1 To whom correspondence should be addressed (email vmueller@bio.uni-frankfurt.de ). 30 10 2012 © The Authors...

...M. Börsch; P. Gräber F-type H + -ATP synthases synthesize ATP from ADP and phosphate using the energy supplied by a transmembrane electrochemical potential difference of protons. Rotary subunit movements within the enzyme drive catalysis in either an ATP hydrolysis or an ATP synthesis direction...