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Keywords: ATP binding and hydrolysis
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Biochem Soc Trans (2021) 49 (1): 405–414.
Published: 26 February 2021
... of the Biochemical Society 2021 ABC transporter allosteric communication ATP binding and hydrolysis conformational transition coupling helix substrate ATP-binding cassette (ABC) transporters are membrane proteins that utilize the energies of ATP binding and hydrolysis to transport various...
Biochem Soc Trans (2005) 33 (5): 1003–1007.
Published: 26 October 2005
... and closing of its anion-selective pore are linked to ATP binding and hydrolysis at CFTR's two NBDs (nucleotide-binding domains), NBD1 and NBD2. Isolated NBDs of prokaryotic ABC proteins form homodimers upon binding ATP, but separate after hydrolysis of the ATP. By combining mutagenesis with single-channel...