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Keywords: ATP
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Articles
Biochem Soc Trans (2020) 48 (1): 103–111.
Published: 03 February 2020
... © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 ACEMBL AMPK ATP ADP AMP biosensor cellular energetics fluorescence resonance energy transfer Energy metabolism is key to cell survival and homeostasis. Metabolic and energy...
Articles
Biochem Soc Trans (2015) 43 (3): 502–507.
Published: 01 June 2015
...Kirk A. Taylor; Joy R. Wright; Martyn P. Mahaut-Smith Pannexin-1 (Panx1) forms anion-selective channels with a permeability up to 1 kDa and represents a pathway for the release of cytosolic ATP. Several structurally similar connexin (Cx) proteins have been identified in platelets and shown to play...
Articles
Biochem Soc Trans (2014) 42 (5): 1311–1315.
Published: 18 September 2014
..., the signalling pathways eliciting glycogen degradation inside astrocytes are themselves energy-demanding processes, a fact that has been emphasized in recent studies, demonstrating dependence of these signalling mechanisms on glycogenolytic ATP. Interestingly, astrocytes can also express α 2 -AR, which as a G...
Articles
Biochem Soc Trans (2014) 42 (5): 1275–1281.
Published: 18 September 2014
..., which maintain the well-being and function of neurons. Still, the study of age-related changes in neuron–glia signalling is far from complete. We have shown previously that cortical astrocytes are capable of releasing ATP by a quantal soluble N -ethylmaleimide-sensitive factor-attachment protein...
Articles
Biochem Soc Trans (2013) 41 (4): 981–986.
Published: 18 July 2013
... by the adenine ring of ATP. In the present paper, we show how the spine concept can be applied to B-Raf, specifically to engineer a kinase-dead pseudokinase. To achieve this, we mutated one of the C-spine residues in the N-lobe (N-terminal lobe), Ala 481 , to phenylalanine. This mutant cannot bind ATP...
Articles
Biochem Soc Trans (2009) 37 (6): 1385–1388.
Published: 19 November 2009
... and ATP insufficiency play closely interlocked roles that may be investigated with primary neuronal cultures. © The Authors Journal compilation © 2009 Biochemical Society 2009 ATP excitotoxicity glutamate ischaemia mitochondrion oxidative stress 1 email dnicholls...
Articles
Biochem Soc Trans (2007) 35 (5): 1264–1268.
Published: 25 October 2007
...G.L. Ackland; V. Kasymov; A.V. Gourine The purine nucleotide ATP mediates several distinct forms of sensory transduction in both the peripheral and central nervous systems. These processes share common mechanisms that involve the release of ATP to activate ionotropic P2X and/or metabotropic P2Y...
Articles
Biochem Soc Trans (2007) 35 (5): 1168–1170.
Published: 25 October 2007
... and the current understanding of the signalling pathways from receptor to RONS generators. BzATP 2′-3′- O -(4-benzoyl)benzoyl ATP JNK1 c-Jun N-terminal kinase 1 MAPK mitogen-activated protein kinase oATP oxidized ATP P2XR P2X receptor P2X 7 R P2X 7 receptor P2YR P2Y...
Articles
Biochem Soc Trans (2003) 31 (6): 1213–1215.
Published: 01 December 2003
...J.A. Eldred; J. Sanderson; M. Wormstone; J.R. Reddan; G. Duncan ATP release has been shown to occur following stimulation in several cellular systems. This study was undertaken to determine if lens and retinal epithelial cells release ATP in response to physiological stresses and to elucidate...
Articles
Biochem Soc Trans (2003) 31 (5): 960–962.
Published: 01 October 2003
...Jenny A. Wilkinson; Ron Jacob [Ca 2+ ] i (cytosolic [Ca 2+ ]) and OS (oxidative stress) were measured simultaneously in calf pulmonary artery endothelial cells using fura-2 and carboxy-2´,7´-dichlorodihydrofluorescein. ATP stimulated a [Ca 2+ ] i increase that was followed a few seconds later...
Articles
Biochem Soc Trans (2002) 30 (2): 227–231.
Published: 01 April 2002
...M. J. Kushmerick; K. E. Conley Understanding muscle energetics is a problem in optimizing supply of ATP to the demands of ATPases. The complexity of reactions and their fluxes to achieve this balance is greatly reduced by recognizing constraints imposed by the integration of common metabolites...