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Keywords: AMP
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Biochem Soc Trans (2020) 48 (1): 103–111.
Published: 03 February 2020
... evolved energy sensing of eukaryotic cells provided by the AMP-activated protein kinase (AMPK). Our synthetic nano-sensor relies on fluorescence resonance energy transfer (FRET) to detect changes in ATP:ADP and ATP:AMP ratios both in vitro and in cells in vivo . Construction and iterative optimisation...