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Keywords: ABCG2
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Articles
Biochem Soc Trans (2016) 44 (3): 824–830.
Published: 09 June 2016
...Aaron J. Horsey; Megan H. Cox; Sunehera Sarwat; Ian D. Kerr ABCG2 is one of at least three human ATP binding cassette (ABC) transporters which can facilitate the export from cells of a wide range of chemically unrelated drug molecules. This capacity for multidrug transport is not only a confounding...
Articles
Biochem Soc Trans (2005) 33 (1): 241–245.
Published: 01 February 2005
... in clinical outcome; however, critical studies aimed at proving the hypothesis using Pgp inhibitors in clinical trials have to date failed. Identification of the MRP (multidrug resistance protein)/ABCC subfamily expanded the possible mechanisms of reduced drug accumulation, and the discovery of ABCG2 added...