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Keywords: ABCB1
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Biochem Soc Trans (2015) 43 (5): 1018–1022.
Published: 09 October 2015
... first relapse. Each of these is consistent with the acquisition of drug and radiotherapy resistance. Since the majority of chemotherapy drugs currently used to treat these patients are transport substrates for ATP-binding cassette sub-family B member 1 (ABCB1) we will address the hypothesis that ABCB1...
Biochem Soc Trans (2015) 43 (5): 1023–1032.
Published: 09 October 2015
...Thomas Stockner; Anna Mullen; Fraser MacMillan ABC transporters are primary active transporters found in all kingdoms of life. Human multidrug resistance transporter ABCB1, or P-glycoprotein, has an extremely broad substrate spectrum and confers resistance against chemotherapy drug treatment...