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Keywords: 5′-cap structureClose
Journal: Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (6): 1544–1546.
Published: 26 October 2005
... that recognizes the 5′-cap structure of the mRNA. Cap recognition by eIF4E, in complex with eIF4G, is essential for recruitment of the mRNA to the small ribosomal subunit. One established mechanism for repressing translation involves eIF4E-binding proteins, which competitively inhibit the eIF4E–eIF4G interaction...