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Keywords: 3D organoidsClose
David A. Parfitt, Amelia Lane, Conor Ramsden, Katarina Jovanovic, Peter J. Coffey, Alison J. Hardcastle, Michael E. Cheetham
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (5): 1245–1251.
Published: 19 October 2016
... in the cilia trafficking of essential photoreceptor cilia proteins, such as RPGR [ 53 ]. The recent study highlights further the potential of using 3D organoids to produce human retinal cells in an appropriate cellular environment to model the effects of gene-specific mutations. The data...