1-6 of 6
Keywords: 2-oxoglutarate
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Biochem Soc Trans (2011) 39 (1): 189–194.
Published: 19 January 2011
... and transport proteins, the great majority of which are involved in cellular nitrogen metabolism. The regulatory activities of P II proteins are mediated through their ability to bind the key effector metabolites 2-OG (2-oxoglutarate), ATP and ADP. However, the molecular basis of these regulatory effects...
Biochem Soc Trans (2009) 37 (1): 291–294.
Published: 20 January 2009
... by PHD (prolyl hydroxylase domain-containing protein) family members. PHD activity depends on the availability of molecular oxygen, making PHDs the oxygen-sensing system in animal cells. However, PHDs have recently been shown to respond to stimuli other than oxygen, such as 2-oxoglutarate (α...
Biochem Soc Trans (2007) 35 (5): 870–875.
Published: 25 October 2007
..., which is then oxidized by β-oxidation. PhyH (phytanoyl-CoA 2-hydroxylase, also known as PAHX), an Fe(II) and 2OG (2-oxoglutarate) oxygenase, catalyses hydroxylation of phytanoyl-CoA. Mutations of PhyH ablate its role in α-oxidation, resulting in PA accumulation and ARD (adult Refsum's disease...
Biochem Soc Trans (2005) 33 (1): 152–156.
Published: 01 February 2005
... through interactions with 2-oxoglutarate, a key metabolic signal of the carbon status, which binds to the N-terminal GAF (c G MP-specific and stimulated phosphodiesterases, A nabaena adenylate cyclases and Escherichia coli F hlA) domain of NifA. NifL–NifA system nitrogen regulation 2-oxoglutarate...
Biochem Soc Trans (2004) 32 (6): 943–945.
Published: 26 October 2004
...D.E. Lancaster; M.A. McDonough; C.J. Schofield FIH (Factor inhibiting hypoxia-inducible factor), an asparaginyl β-hydroxylase belonging to the super-family of 2-oxoglutarate and Fe(II)-dependent dioxygenases, catalyses hydroxylation of Asn-803 of hypoxia-inducible factor, a transcription factor...