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Articles

The role of Klebsiella populations in preterm infants

Anne L. McCartney, Lesley Hoyles
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 887–896.
https://doi.org/10.1042/BST20200325
Published: 26 April 2023
View article titled, The role of Klebsiella populations in preterm infants
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Includes: Supplementary data
Articles

Exploring microRNAs in craniofacial regenerative medicine

Dan Su, Samuel Swearson, Tadkamol Krongbaramee, Hongli Sun, Liu Hong, Brad A. Amendt
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 841–854.
https://doi.org/10.1042/BST20221448
Published: 19 April 2023
View article titled, Exploring microRNAs in craniofacial regenerative medicine
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Articles

Novel roles for G protein-coupled receptor kinases in cardiac injury and repair

Gizem Kayki-Mutlu, Walter J. Koch
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 715–724.
https://doi.org/10.1042/BST20221317
Published: 04 April 2023
View article titled, Novel roles for G protein-coupled receptor kinases in cardiac injury and repair
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Articles

The muscarinic M 4 acetylcholine receptor exacerbates symptoms of movement disorders

Nicole E. Chambers, Michael Millett, Jr, Mark S. Moehle
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 691–702.
https://doi.org/10.1042/BST20220525
Published: 04 April 2023
View article titled, The muscarinic M 4 acetylcholine receptor exacerbates symptoms of movement disorders
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Articles

Allosteric regulation and inhibition of protein kinases

Victoria R. Mingione, YiTing Paung, Ian R. Outhwaite, Markus A. Seeliger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 373–385.
https://doi.org/10.1042/BST20220940
Published: 16 February 2023
View article titled, Allosteric regulation and inhibition of protein kinases
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Articles

Use of invertebrates to model chemically induced parkinsonism-symptoms

Clynton Lourenço Correa, Carlos Augusto Borges de Andrade Gomes, Andressa de Abreu Mello, Nathany da Silva Nogueira, Taiane Barreto Medeiros, Cintia Monteiro de Barros, Silvana Allodi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 435–445.
https://doi.org/10.1042/BST20221172
Published: 16 January 2023
View article titled, Use of invertebrates to model chemically induced parkinsonism-symptoms
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Articles

Targeting the DNA damage response for cancer therapy

In Collection
Awards
Nicola J. Curtin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 207–221.
https://doi.org/10.1042/BST20220681
Published: 06 January 2023
View article titled, Targeting the DNA damage response for cancer therapy
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Articles

Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy

Kendelle J. Murphy, Jessie Zhu, Michael Trpceski, Brooke A. Pereira, Paul Timpson, David Herrmann
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (4): 1129–1141.
https://doi.org/10.1042/BST20220162
Published: 05 August 2022
View article titled, Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy
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Articles

Organ-on-a-chip: current gaps and future directions

Pelin L. Candarlioglu, Gianni Dal Negro, David Hughes, Frances Balkwill, Kate Harris, Hazel Screen, Hywel Morgan, Rhiannon David, Sonja Beken, Olivier Guenat, Wendy Rowan, Augustin Amour
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 665–673.
https://doi.org/10.1042/BST20200661
Published: 19 April 2022
View article titled, Organ-on-a-chip: current gaps and future directions
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Articles

Three-dimensional models of the lung: past, present and future: a mini review

Chandani Sen, Delilah Freund, Brigitte N. Gomperts
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 1045–1056.
https://doi.org/10.1042/BST20190569
Published: 11 April 2022
View article titled, Three-dimensional models of the lung: past, present and future: a mini review
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Articles

Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance

Adithya Balasubramanian, Thomas John, Marie-Liesse Asselin-Labat
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 825–837.
https://doi.org/10.1042/BST20210961
Published: 28 March 2022
View article titled, Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance
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Articles

GCN2: roles in tumour development and progression

Lyssa T. Gold, Glenn R. Masson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 737–745.
https://doi.org/10.1042/BST20211252
Published: 21 March 2022
View article titled, GCN2: roles in tumour development and progression
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Articles

A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences

Chidinma Adanna Okolo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 649–663.
https://doi.org/10.1042/BST20210886
Published: 08 March 2022
View article titled, A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences
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Articles

Npt2a as a target for treating hyperphosphatemia

Linto Thomas, Jessica A. Dominguez Rieg, Timo Rieg
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 439–446.
https://doi.org/10.1042/BST20211005
Published: 07 January 2022
View article titled, Npt2a as a target for treating hyperphosphatemia
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Articles

Spatiotemporal regulation of store-operated calcium entry in cancer metastasis

Fujian Lu, Yunzhan Li, Shengchen Lin, Heping Cheng, Shengyu Yang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2581–2589.
https://doi.org/10.1042/BST20210307
Published: 02 December 2021
View article titled, Spatiotemporal regulation of store-operated calcium entry in cancer metastasis
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Articles

Role of Rho GTPases in stem cell regulation

Zheng Zhang, Ming Liu, Yi Zheng
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2941–2955.
https://doi.org/10.1042/BST20211071
Published: 02 December 2021
View article titled, Role of Rho GTPases in stem cell regulation
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Articles

Quantitative neurogenetics: applications in understanding disease

Ali Afrasiabi, Jeremy T. Keane, Julian Ik-Tsen Heng, Elizabeth E. Palmer, Nigel H. Lovell, Hamid Alinejad-Rokny
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1621–1631.
https://doi.org/10.1042/BST20200732
Published: 20 July 2021
View article titled, Quantitative neurogenetics: applications in understanding disease
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Articles

Recent developments in sustainably sourced protein-based biomaterials

H. Agnieray, J.L. Glasson, Q. Chen, M. Kaur, L.J. Domigan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 953–964.
https://doi.org/10.1042/BST20200896
Published: 17 March 2021
View article titled, Recent developments in sustainably sourced protein-based biomaterials
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Articles

Diverse roles of microRNA-145 in regulating smooth muscle (dys)function in health and disease

Kirsten Riches-Suman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 353–363.
https://doi.org/10.1042/BST20200679
Published: 22 February 2021
View article titled, Diverse roles of microRNA-145 in regulating smooth muscle (dys)function in health and disease
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Articles

The effect of Irisin on bone cells in vivo and in vitro

Cinzia Buccoliero, Angela Oranger, Graziana Colaianni, Patrizia Pignataro, Roberta Zerlotin, Roberto Lovero, Mariella Errede, Maria Grano
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 477–484.
https://doi.org/10.1042/BST20200978
Published: 15 January 2021
View article titled, The effect of Irisin on bone cells in vivo and in vitro
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Articles

Multifaceted roles of long non-coding RNAs in triple-negative breast cancer: biology and clinical applications

Taruna Rajagopal, Srikanth Talluri, Sivaramakrishnan Venkatabalasubramanian, Nageswara Rao Dunna
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2791–2810.
https://doi.org/10.1042/BST20200666
Published: 01 December 2020
View article titled, Multifaceted roles of long non-coding RNAs in triple-negative breast cancer: biology and clinical applications
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Articles

Trehalose 6-phosphate signalling and impact on crop yield

Matthew J. Paul, Amy Watson, Cara A. Griffiths
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2127–2137.
https://doi.org/10.1042/BST20200286
Published: 02 October 2020
View article titled, Trehalose 6-phosphate signalling and impact on crop yield
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Articles

Role of the adaptive immune system in atherosclerosis

Klaus Ley
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2273–2281.
https://doi.org/10.1042/BST20200602
Published: 01 September 2020
View article titled, Role of the adaptive immune system in atherosclerosis
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Articles

Androgens and the masculinization programming window: human–rodent differences

Richard M. Sharpe
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (4): 1725–1735.
https://doi.org/10.1042/BST20200200
Published: 11 August 2020
View article titled, Androgens and the masculinization programming window: human–rodent differences
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Articles

Gut microbiota and metabolites in the pathogenesis of endocrine disease

Aline C. Fenneman, Elena Rampanelli, Yue S. Yin, Jesse Ames, Martin J. Blaser, Eric Fliers, Max Nieuwdorp
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 915–931.
https://doi.org/10.1042/BST20190686
Published: 15 May 2020
View article titled, Gut microbiota and metabolites in the pathogenesis of endocrine disease
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Articles

Systems approach to rational combination therapy: PARP inhibitors

Chaoyang Sun, Yong Fang, Marilyne Labrie, Xi Li, Gordon B. Mills
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1101–1108.
https://doi.org/10.1042/BST20191092
Published: 07 May 2020
View article titled, Systems approach to rational combination therapy: PARP inhibitors
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Articles

Decellularized bone extracellular matrix in skeletal tissue engineering

Benjamin B. Rothrauff, Rocky S. Tuan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 755–764.
https://doi.org/10.1042/BST20190079
Published: 05 May 2020
View article titled, Decellularized bone extracellular matrix in skeletal tissue engineering
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Articles

Post-translational modifications and stress adaptation: the paradigm of FKBP51

Theo Rein
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (2): 441–449.
https://doi.org/10.1042/BST20190332
Published: 22 April 2020
View article titled, Post-translational modifications and stress adaptation: the paradigm of FKBP51
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Articles

How does methotrexate work?

Adel M. Alqarni, Martin P. Zeidler
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (2): 559–567.
https://doi.org/10.1042/BST20190803
Published: 02 April 2020
View article titled, How does methotrexate work?
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Articles

Recent advances in understanding prodrug transport through the SLC15 family of proton-coupled transporters

Gurdeep S. Minhas, Simon Newstead
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (2): 337–346.
https://doi.org/10.1042/BST20180302
Published: 27 March 2020
View article titled, Recent advances in understanding prodrug transport through the SLC15 family of proton-coupled transporters
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Articles

Current research into snake antivenoms, their mechanisms of action and applications

Anjana Silva, Geoffrey K. Isbister
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (2): 537–546.
https://doi.org/10.1042/BST20190739
Published: 20 March 2020
View article titled, Current research into snake antivenoms, their mechanisms of action and applications
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Articles

Extracellular matrix: the gatekeeper of tumor angiogenesis

Maurizio Mongiat, Simone Buraschi, Eva Andreuzzi, Thomas Neill, Renato V. Iozzo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2019) 47 (5): 1543–1555.
https://doi.org/10.1042/BST20190653
Published: 11 October 2019
View article titled, Extracellular matrix: the gatekeeper of tumor angiogenesis
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Articles

Fostering open collaboration in drug development for paediatric brain tumours

Jong Fu Wong, Elizabeth J. Brown, Eleanor Williams, Alex N. Bullock
Journal: Biochemical Society Transactions
Biochem Soc Trans (2019) 47 (5): 1471–1479.
https://doi.org/10.1042/BST20190315
Published: 24 September 2019
View article titled, Fostering open collaboration in drug development for paediatric brain tumours
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Articles

Functional and behavioral consequences of Parkinson's disease-associated LRRK2- G2019S mutation

Deanna L. Benson, Bridget A. Matikainen-Ankney, Ayan Hussein, George W. Huntley
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (6): 1697–1705.
https://doi.org/10.1042/BST20180468
Published: 04 December 2018
View article titled, Functional and behavioral consequences of Parkinson's disease-associated LRRK2- G2019S mutation
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Articles

New perspectives on IL-33 and IL-1 family cytokines as innate environmental sensors

Ian C. Scott, D. Gareth Rees, E. Suzanne Cohen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (5): 1345–1353.
https://doi.org/10.1042/BST20170567
Published: 09 October 2018
View article titled, New perspectives on IL-33 and IL-1 family cytokines as innate environmental sensors
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Articles

Towards a therapy for mitochondrial disease: an update

Caterina Garone, Carlo Viscomi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (5): 1247–1261.
https://doi.org/10.1042/BST20180134
Published: 09 October 2018
View article titled, Towards a therapy for mitochondrial disease: an update
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Articles

Extracellular vesicles: translational challenges and opportunities

Hannah Clemmens, Daniel W. Lambert
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (5): 1073–1082.
https://doi.org/10.1042/BST20180112
Published: 21 September 2018
View article titled, Extracellular vesicles: translational challenges and opportunities
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Articles

The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic

Victoria Casado-Medrano, Martin J. Baker, Cynthia Lopez-Haber, Mariana Cooke, Shaofei Wang, Maria J. Caloca, Marcelo G. Kazanietz
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (4): 1003–1012.
https://doi.org/10.1042/BST20170519
Published: 31 July 2018
View article titled, The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic
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Articles

CBMNet: the ‘Crossing Biological Membranes’ network in industrial biotechnology and bioenergy

Jen Vanderhoven, Jeffrey Green, Gavin H. Thomas
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (4): 871–875.
https://doi.org/10.1042/BST20170532
Published: 19 July 2018
View article titled, CBMNet: the ‘Crossing Biological Membranes’ network in industrial biotechnology and bioenergy
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Articles

Metabolic adjustment to high-altitude hypoxia: from genetic signals to physiological implications

Andrew J. Murray, Hugh E. Montgomery, Martin Feelisch, Michael P.W. Grocott, Daniel S. Martin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (3): 599–607.
https://doi.org/10.1042/BST20170502
Published: 20 April 2018
View article titled, Metabolic adjustment to high-altitude hypoxia: from genetic signals to physiological implications
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Articles

Chitinase-like proteins as regulators of innate immunity and tissue repair: helpful lessons for asthma?

Tara E. Sutherland
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (1): 141–151.
https://doi.org/10.1042/BST20170108
Published: 19 January 2018
View article titled, Chitinase-like proteins as regulators of innate immunity and tissue repair: helpful lessons for asthma?
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Articles

Cell signaling abnormalities in cardiomyopathy caused by lamin A/C gene mutations

Howard J. Worman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (1): 37–42.
https://doi.org/10.1042/BST20170236
Published: 01 December 2017
View article titled, Cell signaling abnormalities in cardiomyopathy caused by lamin A/C gene mutations
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Articles

Omega-3 fatty acids and inflammatory processes: from molecules to man

Philip C. Calder
Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (5): 1105–1115.
https://doi.org/10.1042/BST20160474
Published: 12 September 2017
View article titled, Omega-3 fatty acids and inflammatory processes: from molecules to man
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Articles

Synthetic biology engineering of biofilms as nanomaterials factories

Peter Q. Nguyen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (3): 585–597.
https://doi.org/10.1042/BST20160348
Published: 15 June 2017
View article titled, Synthetic biology engineering of biofilms as nanomaterials factories
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Articles

Mechanisms of LRRK2-dependent neurodegeneration: role of enzymatic activity and protein aggregation

Md. Shariful Islam, Darren J. Moore
Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (1): 163–172.
https://doi.org/10.1042/BST20160264
Published: 15 February 2017
View article titled, Mechanisms of LRRK2-dependent neurodegeneration: role of enzymatic activity and protein aggregation
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Articles

Translating protein phosphatase research into treatments for neurodegenerative diseases

Jeyapriya R. Sundaram, Irene C.J. Lee, Shirish Shenolikar
Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (1): 101–112.
https://doi.org/10.1042/BST20160157
Published: 15 February 2017
View article titled, Translating protein phosphatase research into treatments for neurodegenerative diseases
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Articles

Can the Drosophila model help in paving the way for translational medicine in heart failure?

Lisha Ma
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (5): 1549–1560.
https://doi.org/10.1042/BST20160017C
Published: 19 October 2016
View article titled, Can the Drosophila model help in paving the way for translational medicine in heart failure?
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Articles

Dichotomous roles of TGF-β in human cancer

Jennifer J. Huang, Gerard C. Blobe
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (5): 1441–1454.
https://doi.org/10.1042/BST20160065
Published: 19 October 2016
View article titled, Dichotomous roles of TGF-β in human cancer
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Articles

Toward a therapy for mitochondrial disease

Carlo Viscomi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (5): 1483–1490.
https://doi.org/10.1042/BST20160085
Published: 19 October 2016
View article titled, Toward a therapy for mitochondrial disease
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Articles

Diaphanous-related formin 1 as a target for tumor therapy

Yuan-Na Lin, Sabine Windhorst
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (5): 1289–1293.
https://doi.org/10.1042/BST20160120
Published: 19 October 2016
View article titled, Diaphanous-related formin 1 as a target for tumor therapy
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