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Organ-on-a-chip: current gaps and future directions

Pelin L. Candarlioglu, Gianni Dal Negro, David Hughes, Frances Balkwill, Kate Harris, Hazel Screen, Hywel Morgan, Rhiannon David, Sonja Beken, Olivier Guenat, Wendy Rowan, Augustin Amour

Biochem Soc Trans (2022) 50 (2): 665–673.

DOI: https://doi.org/10.1042/BST20200661

Published: 19 April 2022

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Articles

Three-dimensional models of the lung: past, present and future: a mini review

Chandani Sen, Delilah Freund, Brigitte N. Gomperts

Biochem Soc Trans (2022) 50 (2): 1045–1056.

DOI: https://doi.org/10.1042/BST20190569

Published: 11 April 2022

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Articles

Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance

Adithya Balasubramanian, Thomas John, Marie-Liesse Asselin-Labat

Biochem Soc Trans (2022) 50 (2): 825–837.

DOI: https://doi.org/10.1042/BST20210961

Published: 28 March 2022

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Articles

GCN2: roles in tumour development and progression

Lyssa T. Gold, Glenn R. Masson

Biochem Soc Trans (2022) 50 (2): 737–745.

DOI: https://doi.org/10.1042/BST20211252

Published: 21 March 2022

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A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences

Chidinma Adanna Okolo

Biochem Soc Trans (2022) 50 (2): 649–663.

DOI: https://doi.org/10.1042/BST20210886

Published: 08 March 2022

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Articles

Npt2a as a target for treating hyperphosphatemia

Linto Thomas, Jessica A. Dominguez Rieg, Timo Rieg

Biochem Soc Trans (2022) 50 (1): 439–446.

DOI: https://doi.org/10.1042/BST20211005

Published: 07 January 2022

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Articles

Spatiotemporal regulation of store-operated calcium entry in cancer metastasis

Fujian Lu, Yunzhan Li, Shengchen Lin, Heping Cheng, Shengyu Yang

Biochem Soc Trans (2021) 49 (6): 2581–2589.

DOI: https://doi.org/10.1042/BST20210307

Published: 02 December 2021

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Articles

Role of Rho GTPases in stem cell regulation

Zheng Zhang, Ming Liu, Yi Zheng

Biochem Soc Trans (2021) 49 (6): 2941–2955.

DOI: https://doi.org/10.1042/BST20211071

Published: 02 December 2021

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Articles

Quantitative neurogenetics: applications in understanding disease

Ali Afrasiabi, Jeremy T. Keane, Julian Ik-Tsen Heng, Elizabeth E. Palmer, Nigel H. Lovell, Hamid Alinejad-Rokny

Biochem Soc Trans (2021) 49 (4): 1621–1631.

DOI: https://doi.org/10.1042/BST20200732

Published: 20 July 2021

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Articles

Recent developments in sustainably sourced protein-based biomaterials

H. Agnieray, J.L. Glasson, Q. Chen, M. Kaur, L.J. Domigan

Biochem Soc Trans (2021) 49 (2): 953–964.

DOI: https://doi.org/10.1042/BST20200896

Published: 17 March 2021

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Articles

Diverse roles of microRNA-145 in regulating smooth muscle (dys)function in health and disease

Kirsten Riches-Suman

Biochem Soc Trans (2021) 49 (1): 353–363.

DOI: https://doi.org/10.1042/BST20200679

Published: 22 February 2021

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Articles

The effect of Irisin on bone cells in vivo and in vitro

Cinzia Buccoliero, Angela Oranger, Graziana Colaianni, Patrizia Pignataro, Roberta Zerlotin, Roberto Lovero, Mariella Errede, Maria Grano

Biochem Soc Trans (2021) 49 (1): 477–484.

DOI: https://doi.org/10.1042/BST20200978

Published: 15 January 2021

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Articles

Multifaceted roles of long non-coding RNAs in triple-negative breast cancer: biology and clinical applications

Taruna Rajagopal, Srikanth Talluri, Sivaramakrishnan Venkatabalasubramanian, Nageswara Rao Dunna

Biochem Soc Trans (2020) 48 (6): 2791–2810.

DOI: https://doi.org/10.1042/BST20200666

Published: 01 December 2020

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Articles

Trehalose 6-phosphate signalling and impact on crop yield

Matthew J. Paul, Amy Watson, Cara A. Griffiths

Biochem Soc Trans (2020) 48 (5): 2127–2137.

DOI: https://doi.org/10.1042/BST20200286

Published: 02 October 2020

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Articles

Role of the adaptive immune system in atherosclerosis

Klaus Ley

Biochem Soc Trans (2020) 48 (5): 2273–2281.

DOI: https://doi.org/10.1042/BST20200602

Published: 01 September 2020

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Articles

Androgens and the masculinization programming window: human–rodent differences

Richard M. Sharpe

Biochem Soc Trans (2020) 48 (4): 1725–1735.

DOI: https://doi.org/10.1042/BST20200200

Published: 11 August 2020

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Articles

Gut microbiota and metabolites in the pathogenesis of endocrine disease

Aline C. Fenneman, Elena Rampanelli, Yue S. Yin, Jesse Ames, Martin J. Blaser, Eric Fliers, Max Nieuwdorp

Biochem Soc Trans (2020) 48 (3): 915–931.

DOI: https://doi.org/10.1042/BST20190686

Published: 15 May 2020

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Articles

Systems approach to rational combination therapy: PARP inhibitors

Chaoyang Sun, Yong Fang, Marilyne Labrie, Xi Li, Gordon B. Mills

Biochem Soc Trans (2020) 48 (3): 1101–1108.

DOI: https://doi.org/10.1042/BST20191092

Published: 07 May 2020

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Articles

Decellularized bone extracellular matrix in skeletal tissue engineering

Benjamin B. Rothrauff, Rocky S. Tuan

Biochem Soc Trans (2020) 48 (3): 755–764.

DOI: https://doi.org/10.1042/BST20190079

Published: 05 May 2020

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Articles

Post-translational modifications and stress adaptation: the paradigm of FKBP51

Theo Rein

Biochem Soc Trans (2020) 48 (2): 441–449.

DOI: https://doi.org/10.1042/BST20190332

Published: 22 April 2020

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Articles

How does methotrexate work?

Adel M. Alqarni, Martin P. Zeidler

Biochem Soc Trans (2020) 48 (2): 559–567.

DOI: https://doi.org/10.1042/BST20190803

Published: 02 April 2020

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Articles

Recent advances in understanding prodrug transport through the SLC15 family of proton-coupled transporters

Gurdeep S. Minhas, Simon Newstead

Biochem Soc Trans (2020) 48 (2): 337–346.

DOI: https://doi.org/10.1042/BST20180302

Published: 27 March 2020

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Articles

Current research into snake antivenoms, their mechanisms of action and applications

Anjana Silva, Geoffrey K. Isbister

Biochem Soc Trans (2020) 48 (2): 537–546.

DOI: https://doi.org/10.1042/BST20190739

Published: 20 March 2020

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Articles

Extracellular matrix: the gatekeeper of tumor angiogenesis

Maurizio Mongiat, Simone Buraschi, Eva Andreuzzi, Thomas Neill, Renato V. Iozzo

Biochem Soc Trans (2019) 47 (5): 1543–1555.

DOI: https://doi.org/10.1042/BST20190653

Published: 11 October 2019

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Articles

Fostering open collaboration in drug development for paediatric brain tumours

Jong Fu Wong, Elizabeth J. Brown, Eleanor Williams, Alex N. Bullock

Biochem Soc Trans (2019) 47 (5): 1471–1479.

DOI: https://doi.org/10.1042/BST20190315

Published: 24 September 2019

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Articles

Functional and behavioral consequences of Parkinson's disease-associated LRRK2- G2019S mutation

Deanna L. Benson, Bridget A. Matikainen-Ankney, Ayan Hussein, George W. Huntley

Biochem Soc Trans (2018) 46 (6): 1697–1705.

DOI: https://doi.org/10.1042/BST20180468

Published: 04 December 2018

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Articles

New perspectives on IL-33 and IL-1 family cytokines as innate environmental sensors

Ian C. Scott, D. Gareth Rees, E. Suzanne Cohen

Biochem Soc Trans (2018) 46 (5): 1345–1353.

DOI: https://doi.org/10.1042/BST20170567

Published: 09 October 2018

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Articles

Towards a therapy for mitochondrial disease: an update

Caterina Garone, Carlo Viscomi

Biochem Soc Trans (2018) 46 (5): 1247–1261.

DOI: https://doi.org/10.1042/BST20180134

Published: 09 October 2018

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Articles

Extracellular vesicles: translational challenges and opportunities

Hannah Clemmens, Daniel W. Lambert

Biochem Soc Trans (2018) 46 (5): 1073–1082.

DOI: https://doi.org/10.1042/BST20180112

Published: 21 September 2018

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Articles

The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic

Victoria Casado-Medrano, Martin J. Baker, Cynthia Lopez-Haber, Mariana Cooke, Shaofei Wang, Maria J. Caloca, Marcelo G. Kazanietz

Biochem Soc Trans (2018) 46 (4): 1003–1012.

DOI: https://doi.org/10.1042/BST20170519

Published: 31 July 2018

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Articles

CBMNet: the ‘Crossing Biological Membranes’ network in industrial biotechnology and bioenergy

Jen Vanderhoven, Jeffrey Green, Gavin H. Thomas

Biochem Soc Trans (2018) 46 (4): 871–875.

DOI: https://doi.org/10.1042/BST20170532

Published: 19 July 2018

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Articles

Metabolic adjustment to high-altitude hypoxia: from genetic signals to physiological implications

Andrew J. Murray, Hugh E. Montgomery, Martin Feelisch, Michael P.W. Grocott, Daniel S. Martin

Biochem Soc Trans (2018) 46 (3): 599–607.

DOI: https://doi.org/10.1042/BST20170502

Published: 20 April 2018

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Articles

Chitinase-like proteins as regulators of innate immunity and tissue repair: helpful lessons for asthma?

Tara E. Sutherland

Biochem Soc Trans (2018) 46 (1): 141–151.

DOI: https://doi.org/10.1042/BST20170108

Published: 19 January 2018

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Articles

Cell signaling abnormalities in cardiomyopathy caused by lamin A/C gene mutations

Howard J. Worman

Biochem Soc Trans (2018) 46 (1): 37–42.

DOI: https://doi.org/10.1042/BST20170236

Published: 01 December 2017

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Articles

Omega-3 fatty acids and inflammatory processes: from molecules to man

Philip C. Calder

Biochem Soc Trans (2017) 45 (5): 1105–1115.

DOI: https://doi.org/10.1042/BST20160474

Published: 12 September 2017

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Articles

Synthetic biology engineering of biofilms as nanomaterials factories

Peter Q. Nguyen

Biochem Soc Trans (2017) 45 (3): 585–597.

DOI: https://doi.org/10.1042/BST20160348

Published: 15 June 2017

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Articles

Mechanisms of LRRK2-dependent neurodegeneration: role of enzymatic activity and protein aggregation

Md. Shariful Islam, Darren J. Moore

Biochem Soc Trans (2017) 45 (1): 163–172.

DOI: https://doi.org/10.1042/BST20160264

Published: 15 February 2017

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Articles

Translating protein phosphatase research into treatments for neurodegenerative diseases

Jeyapriya R. Sundaram, Irene C.J. Lee, Shirish Shenolikar

Biochem Soc Trans (2017) 45 (1): 101–112.

DOI: https://doi.org/10.1042/BST20160157

Published: 15 February 2017

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Articles

Can the Drosophila model help in paving the way for translational medicine in heart failure?

Lisha Ma

Biochem Soc Trans (2016) 44 (5): 1549–1560.

DOI: https://doi.org/10.1042/BST20160017C

Published: 19 October 2016

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Articles

Dichotomous roles of TGF-β in human cancer

Jennifer J. Huang, Gerard C. Blobe

Biochem Soc Trans (2016) 44 (5): 1441–1454.

DOI: https://doi.org/10.1042/BST20160065

Published: 19 October 2016

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Articles

Toward a therapy for mitochondrial disease

Carlo Viscomi

Biochem Soc Trans (2016) 44 (5): 1483–1490.

DOI: https://doi.org/10.1042/BST20160085

Published: 19 October 2016

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Articles

Diaphanous-related formin 1 as a target for tumor therapy

Yuan-Na Lin, Sabine Windhorst

Biochem Soc Trans (2016) 44 (5): 1289–1293.

DOI: https://doi.org/10.1042/BST20160120

Published: 19 October 2016

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Articles

Targeting cancer using KAT inhibitors to mimic lethal knockouts

James A.L. Brown, Emer Bourke, Leif A. Eriksson, Michael J. Kerin

Biochem Soc Trans (2016) 44 (4): 979–986.

DOI: https://doi.org/10.1042/BST20160081

Published: 15 August 2016

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