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Articles

Insights into protein structure using cryogenic light microscopy

Hisham Mazal, Franz-Ferdinand Wieser, Vahid Sandoghdar
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) BST20221246.
https://doi.org/10.1042/BST20221246
Published: 28 November 2023
View article titled, Insights into protein structure using cryogenic light microscopy
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Articles

Structural basis of molecular recognition among classical cadherins mediating cell adhesion

Sarbartha Mukherjee, Saumyadeep Goswami, Sagarika Dash, Dibyendu Samanta
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) BST20230356.
https://doi.org/10.1042/BST20230356
Published: 16 November 2023
View article titled, Structural basis of molecular recognition among classical cadherins mediating cell adhesion
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Articles

How to fix DNA breaks: new insights into the mechanism of non-homologous end joining

Alex Vogt, Yuan He, Susan P. Lees-Miller
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1789–1800.
https://doi.org/10.1042/BST20220741
Published: 03 October 2023
View article titled, How to fix DNA breaks: new insights into the mechanism of non-homologous end joining
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Articles

Current working models of SMC-driven DNA-loop extrusion

Kyoung-Wook Moon, Je-Kyung Ryu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1801–1810.
https://doi.org/10.1042/BST20220898
Published: 28 September 2023
View article titled, Current working models of SMC-driven DNA-loop extrusion
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Articles

Insights into the function of cytoglobin

Brandon J. Reeder
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1907–1919.
https://doi.org/10.1042/BST20230081
Published: 18 September 2023
View article titled, Insights into the function of cytoglobin
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Articles

NLR immune receptors: structure and function in plant disease resistance

Alexander Förderer, Jiorgos Kourelis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1473–1483.
https://doi.org/10.1042/BST20221087
Published: 21 August 2023
View article titled, NLR immune receptors: structure and function in plant disease resistance
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Articles

Cryo-electron tomography to study viral infection

Miles Graham, Peijun Zhang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1701–1711.
https://doi.org/10.1042/BST20230103
Published: 10 August 2023
View article titled, Cryo-electron tomography to study viral infection
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Articles

New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures

Matthieu P.M.H. Benoit, Byron Hunter, John S. Allingham, Hernando Sosa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1505–1520.
https://doi.org/10.1042/BST20221238
Published: 10 August 2023
View article titled, New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures
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Includes: Supplementary data
Articles

Unlocking the secrets of ABEs: the molecular mechanism behind their specificity

Xiaoyu Chen, Mitchell J. McAndrew, Audrone Lapinaite
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1635–1646.
https://doi.org/10.1042/BST20221508
Published: 01 August 2023
View article titled, Unlocking the secrets of ABEs: the molecular mechanism behind their specificity
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Articles

Structural insights into NMDA receptor pharmacology

Changping Zhou, Nami Tajima
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1713–1731.
https://doi.org/10.1042/BST20230122
Published: 11 July 2023
View article titled, Structural insights into NMDA receptor pharmacology
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Articles

Regulation of electron transfer in the terminal step of the respiratory chain

Wataru Sato, Koichiro Ishimori
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1611–1619.
https://doi.org/10.1042/BST20221449
Published: 06 July 2023
View article titled, Regulation of electron transfer in the terminal step of the respiratory chain
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Articles

Recent advances in membrane mimetics for membrane protein research

John William Young
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1405–1416.
https://doi.org/10.1042/BST20230164
Published: 22 June 2023
View article titled, Recent advances in membrane mimetics for membrane protein research
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Articles

Conformations, interactions and functions of intrinsically disordered syndecans

Sylvie Ricard-Blum, John R. Couchman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1083–1096.
https://doi.org/10.1042/BST20221085
Published: 19 June 2023
View article titled, Conformations, interactions and functions of intrinsically disordered syndecans
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Articles

Structures and coordination chemistry of transporters involved in manganese and iron homeostasis

Shamayeeta Ray, Rachelle Gaudet
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 897–923.
https://doi.org/10.1042/BST20210699
Published: 07 June 2023
View article titled, Structures and coordination chemistry of transporters involved in manganese and iron homeostasis
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Articles

Fast-forward on P-type ATPases: recent advances on structure and function

Charlott Stock, Tomáš Heger, Sara Basse Hansen, Sigrid Thirup Larsen, Michael Habeck, Thibaud Dieudonné, Ronja Driller, Poul Nissen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1347–1360.
https://doi.org/10.1042/BST20221543
Published: 02 June 2023
View article titled, Fast-forward on P-type ATPases: recent advances on structure and function
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Articles

Cytoophidia and filaments: you must unlearn what you have learned

Chen-Jun Guo, Ji-Long Liu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1245–1256.
https://doi.org/10.1042/BST20221410
Published: 30 May 2023
View article titled, Cytoophidia and filaments: you must unlearn what you have learned
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Articles

The Nrd1–Nab3–Sen1 transcription termination complex from a structural perspective

Belén Chaves-Arquero, José Manuel Pérez-Cañadillas
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1257–1269.
https://doi.org/10.1042/BST20221418
Published: 24 May 2023
View article titled, The Nrd1–Nab3–Sen1 transcription termination complex from a structural perspective
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Includes: Supplementary data
Articles

Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins

Nadezhda A. Aleksandrova, Solace G. Roche, Yu Shang Low, Michael J. Landsberg
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1235–1244.
https://doi.org/10.1042/BST20221409
Published: 18 May 2023
View article titled, Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins
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Articles

The molecular mechanisms of human separase regulation

Jun Yu, David O. Morgan, Andreas Boland
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1225–1233.
https://doi.org/10.1042/BST20221400
Published: 04 May 2023
View article titled, The molecular mechanisms of human separase regulation
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Articles

The molecular mechanisms of the bacterial iron sensor IdeR

Francisco Javier Marcos-Torres, Linda Juniar, Julia J. Griese
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1319–1329.
https://doi.org/10.1042/BST20221539
Published: 04 May 2023
View article titled, The molecular mechanisms of the bacterial iron sensor IdeR
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Articles

Improving the hole picture: towards a consensus on the mechanism of nuclear transport

David Cowburn, Michael Rout
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 871–886.
https://doi.org/10.1042/BST20220494
Published: 26 April 2023
View article titled, Improving the hole picture: towards a consensus on the mechanism of nuclear transport
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Articles

The building blocks of caveolae revealed: caveolins finally take center stage

Anne K. Kenworthy
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 855–869.
https://doi.org/10.1042/BST20221298
Published: 21 April 2023
View article titled, The building blocks of caveolae revealed: caveolins finally take center stage
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Articles

Beyond the matrix: structural and physiological advancements in mitochondrial calcium signaling

Melissa J.S. MacEwen, Yasemin Sancak
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 665–673.
https://doi.org/10.1042/BST20220317
Published: 24 March 2023
View article titled, Beyond the matrix: structural and physiological advancements in mitochondrial calcium signaling
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Articles

Mre11–Rad50: the DNA end game

Karl-Peter Hopfner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 527–538.
https://doi.org/10.1042/BST20220754
Published: 09 March 2023
View article titled, Mre11–Rad50: the DNA end game
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Articles

Allosteric regulation and inhibition of protein kinases

Victoria R. Mingione, YiTing Paung, Ian R. Outhwaite, Markus A. Seeliger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 373–385.
https://doi.org/10.1042/BST20220940
Published: 16 February 2023
View article titled, Allosteric regulation and inhibition of protein kinases
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Articles

Structural insights on the KMT2–NCP interaction

Zi Yang, Robert Zepeda, Yali Dou
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 427–434.
https://doi.org/10.1042/BST20221155
Published: 25 January 2023
View article titled, Structural insights on the KMT2–NCP interaction
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Articles

Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM

Florian Fäßler, Manjunath G. Javoor, Florian KM Schur
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 87–99.
https://doi.org/10.1042/BST20220221
Published: 25 January 2023
View article titled, Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM
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Articles

Structural analysis of mycobacterial electron transport chain complexes by cryoEM

Yingke Liang, John L. Rubinstein
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 183–193.
https://doi.org/10.1042/BST20220611
Published: 20 January 2023
View article titled, Structural analysis of mycobacterial electron transport chain complexes by cryoEM
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Articles

The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder

Katerina Cermakova, Vaclav Veverka, H. Courtney Hodges
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 125–135.
https://doi.org/10.1042/BST20220342
Published: 18 January 2023
View article titled, The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder
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Articles

Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology

Steven Turner, Jonathan W. Essex, Tim Elliott
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 275–285.
https://doi.org/10.1042/BST20220782
Published: 16 January 2023
View article titled, Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology
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Articles

From seeds to trees: how E2 enzymes grow ubiquitin chains

Adam J. Middleton, Catherine L. Day
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 353–362.
https://doi.org/10.1042/BST20220880
Published: 16 January 2023
View article titled, From seeds to trees: how E2 enzymes grow ubiquitin chains
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Articles

Interactions governing transcriptional activity of nuclear receptors

Sabab Hasan Khan, C. Denise Okafor
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1941–1952.
https://doi.org/10.1042/BST20220338
Published: 16 December 2022
View article titled, Interactions governing transcriptional activity of nuclear receptors
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Articles

Lumenal components of cytoplasmic microtubules

Chisato Tsuji, Mark P. Dodding
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1953–1962.
https://doi.org/10.1042/BST20220851
Published: 16 December 2022
View article titled, Lumenal components of cytoplasmic microtubules
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Articles

Deciphering the mechanism and function of Hsp100 unfoldases from protein structure

Grace Lee, Rebecca S. Kim, Sang Bum Lee, Sukyeong Lee, Francis T.F. Tsai
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1725–1736.
https://doi.org/10.1042/BST20220590
Published: 01 December 2022
View article titled, Deciphering the mechanism and function of Hsp100 unfoldases from protein structure
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Articles

Investigating how intrinsically disordered regions contribute to protein function using HDX-MS

Matthew A.H. Parson, Meredith L. Jenkins, John E. Burke
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1607–1617.
https://doi.org/10.1042/BST20220206
Published: 01 December 2022
View article titled, Investigating how intrinsically disordered regions contribute to protein function using HDX-MS
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Articles

Mechanisms of E. coli chemotaxis signaling pathways visualized using cryoET and computational approaches

Kyprianos Hadjidemetriou, Satinder Kaur, C. Keith Cassidy, Peijun Zhang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1595–1605.
https://doi.org/10.1042/BST20220191
Published: 24 November 2022
View article titled, Mechanisms of E. coli chemotaxis signaling pathways visualized using cryoET and computational approaches
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Articles

Structure and function of the peroxisomal ubiquitin ligase complex

Peiqiang Feng, Michael L. Skowyra, Tom A. Rapoport
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1921–1930.
https://doi.org/10.1042/BST20221393
Published: 24 November 2022
View article titled, Structure and function of the peroxisomal ubiquitin ligase complex
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Articles

Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt

Neha Mani, Rie Nygaard, Filippo Mancia
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1763–1772.
https://doi.org/10.1042/BST20220634
Published: 23 November 2022
View article titled, Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt
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Articles

The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI

Dmitry Lyumkis, Nancy C. Horton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1703–1714.
https://doi.org/10.1042/BST20220547
Published: 18 November 2022
View article titled, The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI
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Articles

The role of sensory kinase proteins in two-component signal transduction

Adrián F. Alvarez, Dimitris Georgellis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1859–1873.
https://doi.org/10.1042/BST20220848
Published: 18 November 2022
View article titled, The role of sensory kinase proteins in two-component signal transduction
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Articles

Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation

Benjamin Rowlinson, Elodie Crublet, Rime Kerfah, Michael J. Plevin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1555–1567.
https://doi.org/10.1042/BST20210586
Published: 16 November 2022
View article titled, Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation
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Articles

Characterising ion channel structure and dynamics using fluorescence spectroscopy techniques

Shreyas Bhat, Rikard Blunck
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1427–1445.
https://doi.org/10.1042/BST20220605
Published: 25 October 2022
View article titled, Characterising ion channel structure and dynamics using fluorescence spectroscopy techniques
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Articles

The long and the short of Periscope Proteins

Fiona Whelan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1293–1302.
https://doi.org/10.1042/BST20220194
Published: 05 October 2022
View article titled, The long and the short of Periscope Proteins
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Articles

Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT

Theresa M. Smith, Barry M. Willardson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1403–1414.
https://doi.org/10.1042/BST20220591
Published: 05 October 2022
View article titled, Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT
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Articles

Protective HLA-B57: T cell and natural killer cell recognition in HIV infection

Christian A. Lobos, Jonathan Downing, Lloyd J. D'Orsogna, Demetra S.M. Chatzileontiadou, Stephanie Gras
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1329–1339.
https://doi.org/10.1042/BST20220244
Published: 16 September 2022
View article titled, Protective HLA-B57: T cell and natural killer cell recognition in HIV infection
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Articles

LILBID-MS: using lasers to shed light on biomolecular architectures

Nils Hellwig, Janosch Martin, Nina Morgner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1057–1067.
https://doi.org/10.1042/BST20190881
Published: 13 June 2022
View article titled, LILBID-MS: using lasers to shed light on biomolecular architectures
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Articles

Proteolytic regulation of mitochondrial oxidative phosphorylation components in plants

Abi S. Ghifari, Monika W. Murcha
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1119–1132.
https://doi.org/10.1042/BST20220195
Published: 19 May 2022
View article titled, Proteolytic regulation of mitochondrial oxidative phosphorylation components in plants
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Articles

Quinone binding sites of cyt bc complexes analysed by X-ray crystallography and cryogenic electron microscopy

Wei-Chun Kao, Carola Hunte
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 877–893.
https://doi.org/10.1042/BST20190963
Published: 31 March 2022
View article titled, Quinone binding sites of cyt bc complexes analysed by X-ray crystallography and cryogenic electron microscopy
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Articles

MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Steven R. Van Doren
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 839–851.
https://doi.org/10.1042/BST20210640
Published: 28 March 2022
View article titled, MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains
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Articles

Drug repurposing in silico screening platforms

Jonathan G.L. Mullins
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 747–758.
https://doi.org/10.1042/BST20200967
Published: 14 March 2022
View article titled, Drug repurposing in silico screening platforms
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