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LILBID-MS: using lasers to shed light on biomolecular architectures

Nils Hellwig, Janosch Martin, Nina Morgner

Biochem Soc Trans (2022) BST20190881.

DOI: https://doi.org/10.1042/BST20190881

Published: 13 June 2022

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Articles

Proteolytic regulation of mitochondrial oxidative phosphorylation components in plants

Abi S. Ghifari, Monika W. Murcha

Biochem Soc Trans (2022) BST20220195.

DOI: https://doi.org/10.1042/BST20220195

Published: 19 May 2022

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Quinone binding sites of cyt bc complexes analysed by X-ray crystallography and cryogenic electron microscopy

Wei-Chun Kao, Carola Hunte

Biochem Soc Trans (2022) 50 (2): 877–893.

DOI: https://doi.org/10.1042/BST20190963

Published: 31 March 2022

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MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Steven R. Van Doren

Biochem Soc Trans (2022) 50 (2): 839–851.

DOI: https://doi.org/10.1042/BST20210640

Published: 28 March 2022

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Articles

Drug repurposing in silico screening platforms

Jonathan G.L. Mullins

Biochem Soc Trans (2022) 50 (2): 747–758.

DOI: https://doi.org/10.1042/BST20200967

Published: 14 March 2022

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New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

Valerie B. O'Donnell

Biochem Soc Trans (2022) 50 (1): 1–11.

DOI: https://doi.org/10.1042/BST20210579

Published: 28 February 2022

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Articles

Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?

Ekaterina Shevchenko, Tatu Pantsar

Biochem Soc Trans (2022) 50 (1): 633–648.

DOI: https://doi.org/10.1042/BST20210837

Published: 28 February 2022

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Exploring cryo-electron microscopy with molecular dynamics

John W. Vant, Daipayan Sarkar, Jonathan Nguyen, Alexander T. Baker, Josh V. Vermaas, Abhishek Singharoy

Biochem Soc Trans (2022) 50 (1): 569–581.

DOI: https://doi.org/10.1042/BST20210485

Published: 25 February 2022

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Studying membrane proteins with MicroED

Marc J. Gallenito, Tamir Gonen

Biochem Soc Trans (2022) 50 (1): 231–239.

DOI: https://doi.org/10.1042/BST20210911

Published: 22 February 2022

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Articles

IMPDH dysregulation in disease: a mini review

Anika L. Burrell, Justin M. Kollman

Biochem Soc Trans (2022) 50 (1): 71–82.

DOI: https://doi.org/10.1042/BST20210446

Published: 22 February 2022

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Articles

Conformational ensembles of intrinsically disordered proteins and flexible multidomain proteins

F. Emil Thomasen, Kresten Lindorff-Larsen

Biochem Soc Trans (2022) 50 (1): 541–554.

DOI: https://doi.org/10.1042/BST20210499

Published: 07 February 2022

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Tall tails: cryo-electron microscopy of phage tail DNA ejection conduits

Joshua M. Hardy, Rhys A. Dunstan, Trevor Lithgow, Fasséli Coulibaly

Biochem Soc Trans (2022) 50 (1): 459–22W.

DOI: https://doi.org/10.1042/BST20210799

Published: 07 February 2022

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Articles

Multiple roles of Pol epsilon in eukaryotic chromosome replication

Milos A. Cvetkovic, Esther Ortega, Roberto Bellelli, Alessandro Costa

Biochem Soc Trans (2022) 50 (1): 309–320.

DOI: https://doi.org/10.1042/BST20210082

Published: 07 February 2022

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Articles

Mechanism of action of nucleotide excision repair machinery

Areetha D'Souza, Alexandra M. Blee, Walter J. Chazin

Biochem Soc Trans (2022) 50 (1): 375–386.

DOI: https://doi.org/10.1042/BST20210246

Published: 25 January 2022

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Articles

Three-dimensional insights into human enveloped viruses in vitro and in situ

Naveen Vankadari, Doulin C. Shepherd, Stephen D. Carter, Debnath Ghosal

Biochem Soc Trans (2022) 50 (1): 95–105.

DOI: https://doi.org/10.1042/BST20210433

Published: 25 January 2022

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Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Matthew J. A. Hein, Marc Kvansakul, Fung T. Lay, Thanh Kha Phan, Mark D. Hulett

Biochem Soc Trans (2022) 50 (1): 423–437.

DOI: https://doi.org/10.1042/BST20200884

Published: 11 January 2022

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Articles

Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Jorge Ripoll-Rozada, Joshua W. C. Maxwell, Richard J. Payne, Pedro José Barbosa Pereira

Biochem Soc Trans (2022) 50 (1): 387–401.

DOI: https://doi.org/10.1042/BST20210600

Published: 07 January 2022

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Articles

VDAC2 and the BCL-2 family of proteins

Zheng Yuan, Grant Dewson, Peter E. Czabotar, Richard W. Birkinshaw

Biochem Soc Trans (2021) 49 (6): 2787–2795.

DOI: https://doi.org/10.1042/BST20210753

Published: 16 December 2021

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Articles

Functional characterisation of substrate-binding proteins to address nutrient uptake in marine picocyanobacteria

Benjamin A. Ford, Geraldine J. Sullivan, Lisa Moore, Deepa Varkey, Hannah Zhu, Martin Ostrowski, Bridget C. Mabbutt, Ian T. Paulsen, Bhumika S. Shah

Biochem Soc Trans (2021) 49 (6): 2465–2481.

DOI: https://doi.org/10.1042/BST20200244

Published: 09 December 2021

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Includes: Supplementary data

Articles

Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation

David M. Wood, Renwick C.J. Dobson, Christopher R. Horne

Biochem Soc Trans (2021) 49 (6): 2711–2726.

DOI: https://doi.org/10.1042/BST20210674

Published: 02 December 2021

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Structural and functional approaches to studying cAMP regulation of HCN channels

Andrea Saponaro, Gerhard Thiel, Anna Moroni

Biochem Soc Trans (2021) 49 (6): 2573–2579.

DOI: https://doi.org/10.1042/BST20210290

Published: 23 November 2021

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Articles

Applications of Cryo-EM in small molecule and biologics drug design

Joshua A. Lees, Joao M. Dias, Seungil Han

Biochem Soc Trans (2021) 49 (6): 2627–2638.

DOI: https://doi.org/10.1042/BST20210444

Published: 23 November 2021

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Molecular and structural aspects of gasdermin family pores and insights into gasdermin-elicited programmed cell death

Ayesha Zahid, Hazrat Ismail, Tengchuan Jin

Biochem Soc Trans (2021) 49 (6): 2697–2710.

DOI: https://doi.org/10.1042/BST20210672

Published: 23 November 2021

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Articles

Insights into neurodegeneration from electron microscopy studies

R. Anthony Crowther

Biochem Soc Trans (2021) 49 (6): 2777–2786.

DOI: https://doi.org/10.1042/BST20210719

Published: 23 November 2021

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Articles

Challenges and approaches to studying pore-forming proteins

Joshua T. Benton, Charles Bayly-Jones

Biochem Soc Trans (2021) 49 (6): 2749–2765.

DOI: https://doi.org/10.1042/BST20210706

Published: 08 November 2021

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Articles

Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatin

Akhil Gargey Iragavarapu, Liqi Yao, Vignesh Kasinath

Biochem Soc Trans (2021) 49 (6): 2639–2653.

DOI: https://doi.org/10.1042/BST20210450

Published: 08 November 2021

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Articles

Structural insights into glucocorticoid receptor function

Filipp Frank, Eric A. Ortlund, Xu Liu

Biochem Soc Trans (2021) 49 (5): 2333–2343.

DOI: https://doi.org/10.1042/BST20210419

Published: 28 October 2021

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Articles

Conquer by cryo-EM without physically dividing

Gabriel C. Lander, Robert M. Glaeser

Biochem Soc Trans (2021) 49 (5): 2287–2298.

DOI: https://doi.org/10.1042/BST20210360

Published: 28 October 2021

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Articles

Biophysical characterisation of SMALPs

Stephanie A. Nestorow, Tim R. Dafforn, Verna Frasca

Biochem Soc Trans (2021) 49 (5): 2037–2050.

DOI: https://doi.org/10.1042/BST20201088

Published: 13 October 2021

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Articles

Ca 2+ -dependent modulation of voltage-gated myocyte sodium channels

Samantha C. Salvage, Zaki F. Habib, Hugh R. Matthews, Antony P. Jackson, Christopher L.-H. Huang

Biochem Soc Trans (2021) 49 (5): 1941–1961.

DOI: https://doi.org/10.1042/BST20200604

Published: 13 October 2021

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Articles

Thermodynamic and structural basis of temperature-dependent gating in TRP channels

Ignacio Diaz-Franulic, Christian Verdugo, Felipe Gonzalez, Fernando Gonzalez-Nilo, Ramon Latorre

Biochem Soc Trans (2021) 49 (5): 2211–2219.

DOI: https://doi.org/10.1042/BST20210301

Published: 08 October 2021

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Articles

Structural biology of human telomerase: progress and prospects

Thi Hoang Duong Nguyen

Biochem Soc Trans (2021) 49 (5): 1927–1939.

DOI: https://doi.org/10.1042/BST20200042

Published: 08 October 2021

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Articles

How activated NLRs induce anti-microbial defenses in plants

Farid El Kasmi

Biochem Soc Trans (2021) 49 (5): 2177–2188.

DOI: https://doi.org/10.1042/BST20210242

Published: 08 October 2021

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Articles

Structure determination of GPCRs: cryo-EM compared with X-ray crystallography

Javier García-Nafría, Christopher G. Tate

Biochem Soc Trans (2021) 49 (5): 2345–2355.

DOI: https://doi.org/10.1042/BST20210431

Published: 28 September 2021

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Articles

The pockets guide to HLA class I molecules

Andrea T. Nguyen, Christopher Szeto, Stephanie Gras

Biochem Soc Trans (2021) 49 (5): 2319–2331.

DOI: https://doi.org/10.1042/BST20210410

Published: 28 September 2021

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Articles

Our evolving understanding of the role of the γδ T cell receptor in γδ T cell mediated immunity

Benjamin S. Gully, Jamie Rossjohn, Martin S. Davey

Biochem Soc Trans (2021) 49 (5): 1985–1995.

DOI: https://doi.org/10.1042/BST20200890

Published: 13 September 2021

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Articles

Studying bacterial chemosensory array with CryoEM

Zhuan Qin, Peijun Zhang

Biochem Soc Trans (2021) 49 (5): 2081–2089.

DOI: https://doi.org/10.1042/BST20210080

Published: 08 September 2021

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Articles

Novel insights into the pervasive role of RNA structure in post-transcriptional regulation of gene expression in plants

Huakun Zhang, Yiliang Ding

Biochem Soc Trans (2021) 49 (4): 1829–1839.

DOI: https://doi.org/10.1042/BST20210318

Published: 26 August 2021

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Articles

The BAF chromatin remodeling complexes: structure, function, and synthetic lethalities

Julia Varga, Marie Kube, Katja Luck, Sandra Schick

Biochem Soc Trans (2021) 49 (4): 1489–1503.

DOI: https://doi.org/10.1042/BST20190960

Published: 25 August 2021

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Includes: Supplementary data

Articles

Solid state NMR of membrane proteins: methods and applications

Vivien Yeh, Boyan B. Bonev

Biochem Soc Trans (2021) 49 (4): 1505–1513.

DOI: https://doi.org/10.1042/BST20200070

Published: 16 August 2021

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Articles

U7 deciphered: the mechanism that forms the unusual 3′ end of metazoan replication-dependent histone mRNAs

Zbigniew Dominski, Liang Tong

Biochem Soc Trans (2021) 49 (5): 2229–2240.

DOI: https://doi.org/10.1042/BST20210323

Published: 05 August 2021

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Articles

Polymer models are a versatile tool to study chromatin 3D organization

Andrea Esposito, Simona Bianco, Luca Fiorillo, Mattia Conte, Alex Abraham, Francesco Musella, Mario Nicodemi, Antonella Prisco, Andrea M. Chiariello

Biochem Soc Trans (2021) 49 (4): 1675–1684.

DOI: https://doi.org/10.1042/BST20201004

Published: 20 July 2021

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Articles

Unravelling the structural complexity of protein–lipid interactions with neutron reflectometry

Luke A. Clifton

Biochem Soc Trans (2021) 49 (4): 1537–1546.

DOI: https://doi.org/10.1042/BST20201071

Published: 09 July 2021

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Articles

Molecular subversion of Cdc42 signalling in cancer

Natasha P. Murphy, Ana Masara binti Ahmad Mokhtar, Helen R. Mott, Darerca Owen

Biochem Soc Trans (2021) 49 (3): 1425–1442.

DOI: https://doi.org/10.1042/BST20200557

Published: 01 July 2021

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Articles

Utilizing magnetic resonance techniques to study membrane interactions of amyloid peptides

Sunnia Rajput, Marc-Antoine Sani, David W. Keizer, Frances Separovic

Biochem Soc Trans (2021) 49 (3): 1457–1465.

DOI: https://doi.org/10.1042/BST20201244

Published: 22 June 2021

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Articles

Plant derived cyclic peptides

Norelle L. Daly, David T. Wilson

Biochem Soc Trans (2021) 49 (3): 1279–1285.

DOI: https://doi.org/10.1042/BST20200881

Published: 22 June 2021

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Articles

Detergent-free systems for structural studies of membrane proteins

Youzhong Guo

Biochem Soc Trans (2021) 49 (3): 1361–1374.

DOI: https://doi.org/10.1042/BST20201080

Published: 10 June 2021

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Articles

Biological insights from SMA-extracted proteins

Lucas Unger, Alejandro Ronco-Campaña, Philip Kitchen, Roslyn M. Bill, Alice J. Rothnie

Biochem Soc Trans (2021) 49 (3): 1349–1359.

DOI: https://doi.org/10.1042/BST20201067

Published: 10 June 2021

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The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases

Katherine H. O'Toole, Hannah M. Bernstein, Karen N. Allen, Barbara Imperiali

Biochem Soc Trans (2021) 49 (3): 1189–1203.

DOI: https://doi.org/10.1042/BST20200762

Published: 08 June 2021

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Progress in the therapeutic inhibition of Cdc42 signalling

Natasha P. Murphy, Helen R. Mott, Darerca Owen

Biochem Soc Trans (2021) 49 (3): 1443–1456.

DOI: https://doi.org/10.1042/BST20210112

Published: 08 June 2021

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