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A multi-dimensional view of context-dependent G protein-coupled receptor function

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Maria Marti-Solano

Biochem Soc Trans (2023) BST20210650.

DOI: https://doi.org/10.1042/BST20210650

Published: 23 January 2023

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Articles

The role of post-translational modifications in synaptic AMPA receptor activity

Elisa Corti, Carlos B. Duarte

Biochem Soc Trans (2023) BST20220827.

DOI: https://doi.org/10.1042/BST20220827

Published: 11 January 2023

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Articles

Loss of brain energy metabolism control as a driver for memory impairment upon insulin resistance

João M. N. Duarte

Biochem Soc Trans (2023) BST20220789.

DOI: https://doi.org/10.1042/BST20220789

Published: 06 January 2023

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Articles

The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer

Aristeidis Panagiotis Sfakianos, Rebecca Mallory Raven, Anne Elizabeth Willis

Biochem Soc Trans (2022) 50 (6): 1885–1895.

DOI: https://doi.org/10.1042/BST20221035

Published: 13 December 2022

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Articles

Functional regulation of Wnt protein through post-translational modifications

Jia Yu, David M. Virshup

Biochem Soc Trans (2022) 50 (6): 1797–1808.

DOI: https://doi.org/10.1042/BST20220735

Published: 09 December 2022

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Articles

Is bRaQCing bad? New roles for ribosome associated quality control factors in stress granule regulation

Noah S. Helton, Stephanie L. Moon

Biochem Soc Trans (2022) 50 (6): 1715–1724.

DOI: https://doi.org/10.1042/BST20220549

Published: 09 December 2022

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Articles

Non-kinase targeting of oncogenic c-Jun N-terminal kinase (JNK) signaling: the future of clinically viable cancer treatments

Sharissa L. Latham, Yolande E.I. O'Donnell, David R. Croucher

Biochem Soc Trans (2022) 50 (6): 1823–1836.

DOI: https://doi.org/10.1042/BST20220808

Published: 01 December 2022

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Articles

Mechanisms of E. coli chemotaxis signaling pathways visualized using cryoET and computational approaches

Kyprianos Hadjidemetriou, Satinder Kaur, C. Keith Cassidy, Peijun Zhang

Biochem Soc Trans (2022) 50 (6): 1595–1605.

DOI: https://doi.org/10.1042/BST20220191

Published: 24 November 2022

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Articles

The intracellular signaling pathways governing macrophage activation and function in human atherosclerosis

Heather M. Wilson

Biochem Soc Trans (2022) 50 (6): 1673–1682.

DOI: https://doi.org/10.1042/BST20220441

Published: 23 November 2022

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Articles

Mammalian gastrulation: signalling activity and transcriptional regulation of cell lineage differentiation and germ layer formation

Nazmus Salehin, Hilary Knowles, V. Pragathi Masamsetti, Patrick P.L. Tam

Biochem Soc Trans (2022) 50 (6): 1619–1631.

DOI: https://doi.org/10.1042/BST20220256

Published: 18 November 2022

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Articles

The role of sensory kinase proteins in two-component signal transduction

Adrián F. Alvarez, Dimitris Georgellis

Biochem Soc Trans (2022) 50 (6): 1859–1873.

DOI: https://doi.org/10.1042/BST20220848

Published: 18 November 2022

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Articles

Dynamics of phagocytosis mediated by phosphatidylserine

Daan Vorselen

Biochem Soc Trans (2022) 50 (5): 1281–1291.

DOI: https://doi.org/10.1042/BST20211254

Published: 25 October 2022

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Articles

ERK1/2 in immune signalling

Richard M. Lucas, Lin Luo, Jennifer L. Stow

Biochem Soc Trans (2022) 50 (5): 1341–1352.

DOI: https://doi.org/10.1042/BST20220271

Published: 25 October 2022

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Articles

The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors

Jurre A. Steens, Carl Raymund P. Salazar, Raymond H.J. Staals

Biochem Soc Trans (2022) 50 (5): 1353–1364.

DOI: https://doi.org/10.1042/BST20220289

Published: 25 October 2022

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Articles

The functional importance of VCP to maintaining cellular protein homeostasis

Brittany A. Ahlstedt, Rakesh Ganji, Malavika Raman

Biochem Soc Trans (2022) 50 (5): 1457–1469.

DOI: https://doi.org/10.1042/BST20220648

Published: 05 October 2022

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Articles

Regulation of ATR–CHK1 signaling by ubiquitination of CLASPIN

Xuefei Zhu, Xiang-Yang Zheng, Peng Gong, Xingzhi Xu

Biochem Soc Trans (2022) 50 (5): 1471–1480.

DOI: https://doi.org/10.1042/BST20220729

Published: 05 October 2022

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The role of RHIM in necroptosis

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Cell death and survival

Theresa Riebeling, Ulrich Kunzendorf, Stefan Krautwald

Biochem Soc Trans (2022) 50 (4): 1197–1205.

DOI: https://doi.org/10.1042/BST20220535

Published: 30 August 2022

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Articles

CDKL5 deficiency disorder: molecular insights and mechanisms of pathogenicity to fast-track therapeutic development

Nicole J. Van Bergen, Sean Massey, Anita Quigley, Ben Rollo, Alexander R. Harris, Robert M.I. Kapsa, John Christodoulou

Biochem Soc Trans (2022) 50 (4): 1207–1224.

DOI: https://doi.org/10.1042/BST20220791

Published: 23 August 2022

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Articles

Two-pore channels: going with the flows

Anthony J. Morgan, Lora L. Martucci, Lianne C. Davis, Antony Galione

Biochem Soc Trans (2022) 50 (4): 1143–1155.

DOI: https://doi.org/10.1042/BST20220229

Published: 12 August 2022

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Articles

Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy

Kendelle J. Murphy, Jessie Zhu, Michael Trpceski, Brooke A. Pereira, Paul Timpson, David Herrmann

Biochem Soc Trans (2022) 50 (4): 1129–1141.

DOI: https://doi.org/10.1042/BST20220162

Published: 05 August 2022

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Articles

The intersection between circadian and heat-responsive regulatory networks controls plant responses to increasing temperatures

Kanjana Laosuntisuk, Colleen J. Doherty

Biochem Soc Trans (2022) 50 (3): 1151–1165.

DOI: https://doi.org/10.1042/BST20190572

Published: 27 June 2022

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Articles

The evolution and structure/function of bHLH–PAS transcription factor family

Hailey E. Edwards, Daniel A. Gorelick

Biochem Soc Trans (2022) 50 (3): 1227–1243.

DOI: https://doi.org/10.1042/BST20211225

Published: 13 June 2022

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Articles

Functional diversity in the RAS subfamily of small GTPases

Gabriela Bernal Astrain, Maya Nikolova, Matthew J. Smith

Biochem Soc Trans (2022) 50 (2): 921–933.

DOI: https://doi.org/10.1042/BST20211166

Published: 31 March 2022

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Articles

Understanding immune signaling using advanced imaging techniques

Mario Brameshuber, Enrico Klotzsch, Aleks Ponjavic, Erdinc Sezgin

Biochem Soc Trans (2022) 50 (2): 853–866.

DOI: https://doi.org/10.1042/BST20210479

Published: 28 March 2022

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Articles

PIDD1 in cell cycle control, sterile inflammation and cell death

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Cell death and survival

Elias S. Weiler, Tamas G. Szabo, Irmina Garcia-Carpio, Andreas Villunger

Biochem Soc Trans (2022) 50 (2): 813–824.

DOI: https://doi.org/10.1042/BST20211186

Published: 28 March 2022

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Articles

Computational exploration of cellular communication in skin from emerging single-cell and spatial transcriptomic data

Suoqin Jin, Raul Ramos

Biochem Soc Trans (2022) 50 (1): 297–308.

DOI: https://doi.org/10.1042/BST20210863

Published: 22 February 2022

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Bioimaging approaches for quantification of individual cell behavior during cell fate decisions

Karine R. Begnini, Luiza C. Pereira, Juliano L. Faccioni, Guido Lenz, Eduardo C. Filippi-Chiela

Biochem Soc Trans (2022) 50 (1): 513–527.

DOI: https://doi.org/10.1042/BST20210534

Published: 15 February 2022

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Articles

Inferiority complex: why do sensory ion channels multimerize?

Nikita Gamper, Shihab Shah

Biochem Soc Trans (2022) 50 (1): 213–222.

DOI: https://doi.org/10.1042/BST20211002

Published: 15 February 2022

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Articles

The role of IL-36 subfamily in intestinal disease

Peng Xu, Haidi Guan, Weidong Xiao, Lihua Sun

Biochem Soc Trans (2022) 50 (1): 223–230.

DOI: https://doi.org/10.1042/BST20211264

Published: 15 February 2022

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Articles

Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

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Cell death and survival

Sarah E. Garnish, Joanne M. Hildebrand

Biochem Soc Trans (2022) 50 (1): 529–539.

DOI: https://doi.org/10.1042/BST20210517

Published: 15 February 2022

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Articles

The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation

Daria Sicari, Janine Weber, Elena Maspero, Simona Polo

Biochem Soc Trans (2022) 50 (1): 473–485.

DOI: https://doi.org/10.1042/BST20210731

Published: 07 February 2022

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Articles

The role of caspases as executioners of apoptosis

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Cell death and survival

Sharad Kumar, Loretta Dorstyn, Yoon Lim

Biochem Soc Trans (2022) 50 (1): 33–45.

DOI: https://doi.org/10.1042/BST20210751

Published: 23 December 2021

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Articles

Spatiotemporal regulation of store-operated calcium entry in cancer metastasis

Fujian Lu, Yunzhan Li, Shengchen Lin, Heping Cheng, Shengyu Yang

Biochem Soc Trans (2021) 49 (6): 2581–2589.

DOI: https://doi.org/10.1042/BST20210307

Published: 02 December 2021

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Articles

Role of Rho GTPases in stem cell regulation

Zheng Zhang, Ming Liu, Yi Zheng

Biochem Soc Trans (2021) 49 (6): 2941–2955.

DOI: https://doi.org/10.1042/BST20211071

Published: 02 December 2021

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Articles

PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

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Cell death and survival

Chloe M. McKee, Fabian A. Fischer, Jelena S. Bezbradica, Rebecca C. Coll

Biochem Soc Trans (2021) 49 (6): 2495–2507.

DOI: https://doi.org/10.1042/BST20200987

Published: 02 December 2021

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Articles

Itaconate as an inflammatory mediator and therapeutic target in cardiovascular medicine

Marina Diotallevi, Faseeha Ayaz, Thomas Nicol, Mark J. Crabtree

Biochem Soc Trans (2021) 49 (5): 2189–2198.

DOI: https://doi.org/10.1042/BST20210269

Published: 19 October 2021

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Articles

The dynamics of mitochondrial autophagy at the initiation stage

Nicholas T. Ktistakis

Biochem Soc Trans (2021) 49 (5): 2199–2210.

DOI: https://doi.org/10.1042/BST20210272

Published: 19 October 2021

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Articles

Targeting small GTPases and their downstream pathways with intracellular macromolecule binders to define alternative therapeutic strategies in cancer

Marie Sorbara, Nicolas Bery

Biochem Soc Trans (2021) 49 (5): 2021–2035.

DOI: https://doi.org/10.1042/BST20201059

Published: 08 October 2021

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An integrated view of innate immune mechanisms in C. elegans

Benjamin W. Harding, Jonathan J. Ewbank

Biochem Soc Trans (2021) 49 (5): 2307–2317.

DOI: https://doi.org/10.1042/BST20210399

Published: 08 October 2021

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Articles

Correlative nanophotonic approaches to enlighten the nanoscale dynamics of living cell membranes

Pamina M. Winkler, María F. García-Parajo

Biochem Soc Trans (2021) 49 (5): 2357–2369.

DOI: https://doi.org/10.1042/BST20210457

Published: 08 September 2021

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Progress and challenges in understanding the regulation and function of p53 dynamics

Zhilin Yang, Ryan L. Hanson, Eric Batchelor

Biochem Soc Trans (2021) 49 (5): 2123–2131.

DOI: https://doi.org/10.1042/BST20210148

Published: 08 September 2021

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Articles

Studying bacterial chemosensory array with CryoEM

Zhuan Qin, Peijun Zhang

Biochem Soc Trans (2021) 49 (5): 2081–2089.

DOI: https://doi.org/10.1042/BST20210080

Published: 08 September 2021

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Articles

The role of pro-domains in human growth factors and cytokines

Matthew Ratcliff, Richard Xu Zhou, Lutz Jermutus, Marko Hyvönen

Biochem Soc Trans (2021) 49 (5): 1963–1973.

DOI: https://doi.org/10.1042/BST20200663

Published: 08 September 2021

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Articles

Profiling novel pharmacology of receptor complexes using Receptor-HIT

Elizabeth K.M. Johnstone, Kevin D.G. Pfleger

Biochem Soc Trans (2021) 49 (4): 1555–1565.

DOI: https://doi.org/10.1042/BST20201110

Published: 26 August 2021

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Functional interrogation and therapeutic targeting of protein tyrosine phosphatases

Aaron D. Krabill, Zhong-Yin Zhang

Biochem Soc Trans (2021) 49 (4): 1723–1734.

DOI: https://doi.org/10.1042/BST20201308

Published: 25 August 2021

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Microglia extracellular vesicles: focus on molecular composition and biological function

Lorenzo Ceccarelli, Chiara Giacomelli, Laura Marchetti, Claudia Martini

Biochem Soc Trans (2021) 49 (4): 1779–1790.

DOI: https://doi.org/10.1042/BST20210202

Published: 20 August 2021

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Cellular feedback dynamics and multilevel regulation driven by the hippo pathway

Jiwon Park, Carsten Gram Hansen

Biochem Soc Trans (2021) 49 (4): 1515–1527.

DOI: https://doi.org/10.1042/BST20200253

Published: 10 August 2021

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Articles

Host ADP-ribosylation and the SARS-CoV-2 macrodomain

Nicolas C. Hoch

Biochem Soc Trans (2021) 49 (4): 1711–1721.

DOI: https://doi.org/10.1042/BST20201212

Published: 05 August 2021

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Are cachexia-associated tumors transmitTERS of ER stress?

Ana Sayuri Yamagata, Paula Paccielli Freire

Biochem Soc Trans (2021) 49 (4): 1841–1853.

DOI: https://doi.org/10.1042/BST20210496

Published: 02 August 2021

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The Hitchhiker's guide to glycoproteomics

Tiago Oliveira, Morten Thaysen-Andersen, Nicolle H. Packer, Daniel Kolarich

Biochem Soc Trans (2021) 49 (4): 1643–1662.

DOI: https://doi.org/10.1042/BST20200879

Published: 20 July 2021

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