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Functional diversity in the RAS subfamily of small GTPases

Gabriela Bernal Astrain, Maya Nikolova, Matthew J. Smith

Biochem Soc Trans (2022) 50 (2): 921–933.

DOI: https://doi.org/10.1042/BST20211166

Published: 31 March 2022

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Articles

Understanding immune signaling using advanced imaging techniques

Mario Brameshuber, Enrico Klotzsch, Aleks Ponjavic, Erdinc Sezgin

Biochem Soc Trans (2022) 50 (2): 853–866.

DOI: https://doi.org/10.1042/BST20210479

Published: 28 March 2022

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Articles

PIDD1 in cell cycle control, sterile inflammation and cell death

Elias S. Weiler, Tamas G. Szabo, Irmina Garcia-Carpio, Andreas Villunger

Biochem Soc Trans (2022) 50 (2): 813–824.

DOI: https://doi.org/10.1042/BST20211186

Published: 28 March 2022

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Articles

Computational exploration of cellular communication in skin from emerging single-cell and spatial transcriptomic data

Suoqin Jin, Raul Ramos

Biochem Soc Trans (2022) 50 (1): 297–308.

DOI: https://doi.org/10.1042/BST20210863

Published: 22 February 2022

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Articles

Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

Sarah E. Garnish, Joanne M. Hildebrand

Biochem Soc Trans (2022) 50 (1): 529–539.

DOI: https://doi.org/10.1042/BST20210517

Published: 15 February 2022

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Articles

Bioimaging approaches for quantification of individual cell behavior during cell fate decisions

Karine R. Begnini, Luiza C. Pereira, Juliano L. Faccioni, Guido Lenz, Eduardo C. Filippi-Chiela

Biochem Soc Trans (2022) 50 (1): 513–527.

DOI: https://doi.org/10.1042/BST20210534

Published: 15 February 2022

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Articles

Inferiority complex: why do sensory ion channels multimerize?

Nikita Gamper, Shihab Shah

Biochem Soc Trans (2022) 50 (1): 213–222.

DOI: https://doi.org/10.1042/BST20211002

Published: 15 February 2022

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Articles

The role of IL-36 subfamily in intestinal disease

Peng Xu, Haidi Guan, Weidong Xiao, Lihua Sun

Biochem Soc Trans (2022) 50 (1): 223–230.

DOI: https://doi.org/10.1042/BST20211264

Published: 15 February 2022

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Articles

The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation

Daria Sicari, Janine Weber, Elena Maspero, Simona Polo

Biochem Soc Trans (2022) 50 (1): 473–485.

DOI: https://doi.org/10.1042/BST20210731

Published: 07 February 2022

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Articles

The role of caspases as executioners of apoptosis

Sharad Kumar, Loretta Dorstyn, Yoon Lim

Biochem Soc Trans (2022) 50 (1): 33–45.

DOI: https://doi.org/10.1042/BST20210751

Published: 23 December 2021

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Articles

Spatiotemporal regulation of store-operated calcium entry in cancer metastasis

Fujian Lu, Yunzhan Li, Shengchen Lin, Heping Cheng, Shengyu Yang

Biochem Soc Trans (2021) 49 (6): 2581–2589.

DOI: https://doi.org/10.1042/BST20210307

Published: 02 December 2021

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Articles

Role of Rho GTPases in stem cell regulation

Zheng Zhang, Ming Liu, Yi Zheng

Biochem Soc Trans (2021) 49 (6): 2941–2955.

DOI: https://doi.org/10.1042/BST20211071

Published: 02 December 2021

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Articles

PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

Chloe M. McKee, Fabian A. Fischer, Jelena S. Bezbradica, Rebecca C. Coll

Biochem Soc Trans (2021) 49 (6): 2495–2507.

DOI: https://doi.org/10.1042/BST20200987

Published: 02 December 2021

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Articles

The dynamics of mitochondrial autophagy at the initiation stage

Nicholas T. Ktistakis

Biochem Soc Trans (2021) 49 (5): 2199–2210.

DOI: https://doi.org/10.1042/BST20210272

Published: 19 October 2021

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Articles

Itaconate as an inflammatory mediator and therapeutic target in cardiovascular medicine

Marina Diotallevi, Faseeha Ayaz, Thomas Nicol, Mark J. Crabtree

Biochem Soc Trans (2021) 49 (5): 2189–2198.

DOI: https://doi.org/10.1042/BST20210269

Published: 19 October 2021

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Articles

Targeting small GTPases and their downstream pathways with intracellular macromolecule binders to define alternative therapeutic strategies in cancer

Marie Sorbara, Nicolas Bery

Biochem Soc Trans (2021) 49 (5): 2021–2035.

DOI: https://doi.org/10.1042/BST20201059

Published: 08 October 2021

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Articles

An integrated view of innate immune mechanisms in C. elegans

Benjamin W. Harding, Jonathan J. Ewbank

Biochem Soc Trans (2021) 49 (5): 2307–2317.

DOI: https://doi.org/10.1042/BST20210399

Published: 08 October 2021

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Articles

The role of pro-domains in human growth factors and cytokines

Matthew Ratcliff, Richard Xu Zhou, Lutz Jermutus, Marko Hyvönen

Biochem Soc Trans (2021) 49 (5): 1963–1973.

DOI: https://doi.org/10.1042/BST20200663

Published: 08 September 2021

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Articles

Correlative nanophotonic approaches to enlighten the nanoscale dynamics of living cell membranes

Pamina M. Winkler, María F. García-Parajo

Biochem Soc Trans (2021) 49 (5): 2357–2369.

DOI: https://doi.org/10.1042/BST20210457

Published: 08 September 2021

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Articles

Studying bacterial chemosensory array with CryoEM

Zhuan Qin, Peijun Zhang

Biochem Soc Trans (2021) 49 (5): 2081–2089.

DOI: https://doi.org/10.1042/BST20210080

Published: 08 September 2021

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Articles

Progress and challenges in understanding the regulation and function of p53 dynamics

Zhilin Yang, Ryan L. Hanson, Eric Batchelor

Biochem Soc Trans (2021) 49 (5): 2123–2131.

DOI: https://doi.org/10.1042/BST20210148

Published: 08 September 2021

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Articles

Profiling novel pharmacology of receptor complexes using Receptor-HIT

Elizabeth K.M. Johnstone, Kevin D.G. Pfleger

Biochem Soc Trans (2021) 49 (4): 1555–1565.

DOI: https://doi.org/10.1042/BST20201110

Published: 26 August 2021

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Articles

Functional interrogation and therapeutic targeting of protein tyrosine phosphatases

Aaron D. Krabill, Zhong-Yin Zhang

Biochem Soc Trans (2021) 49 (4): 1723–1734.

DOI: https://doi.org/10.1042/BST20201308

Published: 25 August 2021

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Articles

Microglia extracellular vesicles: focus on molecular composition and biological function

Lorenzo Ceccarelli, Chiara Giacomelli, Laura Marchetti, Claudia Martini

Biochem Soc Trans (2021) 49 (4): 1779–1790.

DOI: https://doi.org/10.1042/BST20210202

Published: 20 August 2021

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Articles

Cellular feedback dynamics and multilevel regulation driven by the hippo pathway

Jiwon Park, Carsten Gram Hansen

Biochem Soc Trans (2021) 49 (4): 1515–1527.

DOI: https://doi.org/10.1042/BST20200253

Published: 10 August 2021

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Articles

Host ADP-ribosylation and the SARS-CoV-2 macrodomain

Nicolas C. Hoch

Biochem Soc Trans (2021) 49 (4): 1711–1721.

DOI: https://doi.org/10.1042/BST20201212

Published: 05 August 2021

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Articles

Are cachexia-associated tumors transmitTERS of ER stress?

Ana Sayuri Yamagata, Paula Paccielli Freire

Biochem Soc Trans (2021) 49 (4): 1841–1853.

DOI: https://doi.org/10.1042/BST20210496

Published: 02 August 2021

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Articles

The Hitchhiker's guide to glycoproteomics

Tiago Oliveira, Morten Thaysen-Andersen, Nicolle H. Packer, Daniel Kolarich

Biochem Soc Trans (2021) 49 (4): 1643–1662.

DOI: https://doi.org/10.1042/BST20200879

Published: 20 July 2021

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Articles

Emerging roles of adhesion G protein-coupled receptors

Matthew Rosa, Timothy Noel, Matthew Harris, Graham Ladds

Biochem Soc Trans (2021) 49 (4): 1695–1709.

DOI: https://doi.org/10.1042/BST20201144

Published: 20 July 2021

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Articles

Protein Phosphatase 2A (PP2A) mutations in brain function, development, and neurologic disease

Iris Verbinnen, Pieter Vaneynde, Sara Reynhout, Lisa Lenaerts, Rita Derua, Gunnar Houge, Veerle Janssens

Biochem Soc Trans (2021) 49 (4): 1567–1588.

DOI: https://doi.org/10.1042/BST20201313

Published: 09 July 2021

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Articles

Transcriptional control of ribosome biogenesis in yeast: links to growth and stress signals

David Shore, Sevil Zencir, Benjamin Albert

Biochem Soc Trans (2021) 49 (4): 1589–1599.

DOI: https://doi.org/10.1042/BST20201136

Published: 09 July 2021

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Articles

Clues to the function of bacterial microcompartments from ancillary genes

Henning Kirst, Cheryl A. Kerfeld

Biochem Soc Trans (2021) 49 (3): 1085–1098.

DOI: https://doi.org/10.1042/BST20200632

Published: 01 July 2021

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Includes: Supplementary data

Articles

Molecular subversion of Cdc42 signalling in cancer

Natasha P. Murphy, Ana Masara binti Ahmad Mokhtar, Helen R. Mott, Darerca Owen

Biochem Soc Trans (2021) 49 (3): 1425–1442.

DOI: https://doi.org/10.1042/BST20200557

Published: 01 July 2021

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Articles

The cellular pathways and potential therapeutics of Polycystic Kidney Disease

Taylor Richards, Kavindiya Modarage, Soniya A. Malik, Paraskevi Goggolidou

Biochem Soc Trans (2021) 49 (3): 1171–1188.

DOI: https://doi.org/10.1042/BST20200757

Published: 22 June 2021

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Articles

The HSP70 chaperone as sensor of the NEDD8 cycle upon DNA damage

Aymeric P. Bailly, Dimitris P. Xirodimas

Biochem Soc Trans (2021) 49 (3): 1075–1083.

DOI: https://doi.org/10.1042/BST20200381

Published: 22 June 2021

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Articles

Roles for growth factors and mutations in metastatic dissemination

Nishanth Belugali Nataraj, Ilaria Marrocco, Yosef Yarden

Biochem Soc Trans (2021) 49 (3): 1409–1423.

DOI: https://doi.org/10.1042/BST20210048

Published: 08 June 2021

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Articles

Evolutionary crossroads of cell signaling: PP1 and PP2A substrate sites in intrinsically disordered regions

Bernhard Hoermann, Maja Köhn

Biochem Soc Trans (2021) 49 (3): 1065–1074.

DOI: https://doi.org/10.1042/BST20200175

Published: 08 June 2021

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Articles

Latest update on chemokine receptors as therapeutic targets

Wing Yee Lai, Anja Mueller

Biochem Soc Trans (2021) 49 (3): 1385–1395.

DOI: https://doi.org/10.1042/BST20201114

Published: 01 June 2021

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Articles

Great balls of fire: activation and signalling of inflammatory caspases

Georgia Bateman, Benjamin Hill, Ryan Knight, Dave Boucher

Biochem Soc Trans (2021) 49 (3): 1311–1324.

DOI: https://doi.org/10.1042/BST20200986

Published: 01 June 2021

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Articles

Transcription factors regulated by cAMP in smooth muscle of the myometrium at human parturition

Jonathan K.H. Li, Pei F. Lai, Rachel M. Tribe, Mark R. Johnson

Biochem Soc Trans (2021) 49 (2): 997–1011.

DOI: https://doi.org/10.1042/BST20201173

Published: 16 April 2021

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Articles

Regulation of MST complexes and activity via SARAH domain modifications

Sofiia Karchugina, Dorothy Benton, Jonathan Chernoff

Biochem Soc Trans (2021) 49 (2): 675–683.

DOI: https://doi.org/10.1042/BST20200559

Published: 16 April 2021

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Articles

State of the structure address on MET receptor activation by HGF

Edmond M. Linossi, Gabriella O. Estevam, Masaya Oshima, James S. Fraser, Eric A. Collisson, Natalia Jura

Biochem Soc Trans (2021) 49 (2): 645–661.

DOI: https://doi.org/10.1042/BST20200394

Published: 16 April 2021

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Articles

Primary cilia and the DNA damage response: linking a cellular antenna and nuclear signals

Ciaran G. Morrison

Biochem Soc Trans (2021) 49 (2): 829–841.

DOI: https://doi.org/10.1042/BST20200751

Published: 12 April 2021

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Articles

Parkinson's disease and mitophagy: an emerging role for LRRK2

Francois Singh, Ian G. Ganley

Biochem Soc Trans (2021) 49 (2): 551–562.

DOI: https://doi.org/10.1042/BST20190236

Published: 26 March 2021

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Articles

The regulation of the DNA damage response at telomeres: focus on kinases

Michela Galli, Chiara Frigerio, Maria Pia Longhese, Michela Clerici

Biochem Soc Trans (2021) 49 (2): 933–943.

DOI: https://doi.org/10.1042/BST20200856

Published: 26 March 2021

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Articles

Mechanisms of mitochondrial cell death

Shashank Dadsena, Cristiana Zollo, Ana J. García-Sáez

Biochem Soc Trans (2021) 49 (2): 663–674.

DOI: https://doi.org/10.1042/BST20200522

Published: 11 March 2021

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Articles

Class II phosphatidylinositol 3-kinase isoforms in vesicular trafficking

Kazuaki Yoshioka

Biochem Soc Trans (2021) 49 (2): 893–901.

DOI: https://doi.org/10.1042/BST20200835

Published: 05 March 2021

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Articles

Type-2 diabetes, a co-morbidity in Covid-19: does insulin signaling matter?

Devanshi Mishra, Chinmoy Sankar Dey

Biochem Soc Trans (2021) 49 (2): 987–995.

DOI: https://doi.org/10.1042/BST20201062

Published: 05 March 2021

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Articles

It's not just a phase; ubiquitination in cytosolic protein quality control

Heather A. Baker, Jonathan P. Bernardini

Biochem Soc Trans (2021) 49 (1): 365–377.

DOI: https://doi.org/10.1042/BST20200694

Published: 26 February 2021

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Articles

CHCHD4 (MIA40) and the mitochondrial disulfide relay system

Hasan Al-Habib, Margaret Ashcroft

Biochem Soc Trans (2021) 49 (1): 17–27.

DOI: https://doi.org/10.1042/BST20190232

Published: 18 February 2021

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