Page 1 | Search Results | Biochemical Society Transactions

1-50 of 146

Sort by

Sort Order Select

Articles

The enzymes of the oxidative phase of the pentose phosphate pathway as targets of reactive species: consequences for NADPH production

Eduardo Fuentes-Lemus, Juan Sebastián Reyes, Juan David Figueroa, Michael J. Davies, Camilo López-Alarcón

Biochem Soc Trans (2023) BST20231027.

https://doi.org/10.1042/BST20231027

Published: 16 November 2023

View article titled, The enzymes of the oxidative phase of the pentose phosphate pathway as targets of reactive species: consequences for NADPH production

Articles

How to fix DNA breaks: new insights into the mechanism of non-homologous end joining

Alex Vogt, Yuan He, Susan P. Lees-Miller

Biochem Soc Trans (2023) 51 (5): 1789–1800.

https://doi.org/10.1042/BST20220741

Published: 03 October 2023

View article titled, How to fix DNA breaks: new insights into the mechanism of non-homologous end joining

Articles

The role of lipid scramblases in regulating lipid distributions at cellular membranes

Yicheng Wang, Taroh Kinoshita

Biochem Soc Trans (2023) 51 (5): 1857–1869.

https://doi.org/10.1042/BST20221455

Published: 28 September 2023

View article titled, The role of lipid scramblases in regulating lipid distributions at cellular membranes

Articles

Recent advances in the structure and activation mechanisms of metabolite-releasing Pannexin 1 channels

Yi-Ling Wu, Ai-Hsing Yang, Yu-Hsin Chiu

Biochem Soc Trans (2023) 51 (4): 1687–1699.

https://doi.org/10.1042/BST20230038

Published: 25 August 2023

View article titled, Recent advances in the structure and activation mechanisms of metabolite-releasing Pannexin 1 channels

Articles

The central role of translation elongation in response to stress

Géssica C. Barros, Sofia Guerrero, Gustavo M. Silva

Biochem Soc Trans (2023) 51 (3): 959–969.

https://doi.org/10.1042/BST20220584

Published: 15 June 2023

View article titled, The central role of translation elongation in response to stress

Articles

Fast-forward on P-type ATPases: recent advances on structure and function

Charlott Stock, Tomáš Heger, Sara Basse Hansen, Sigrid Thirup Larsen, Michael Habeck, Thibaud Dieudonné, Ronja Driller, Poul Nissen

Biochem Soc Trans (2023) 51 (3): 1347–1360.

https://doi.org/10.1042/BST20221543

Published: 02 June 2023

View article titled, Fast-forward on P-type ATPases: recent advances on structure and function

Articles

Differential functions of the KRAS splice variants

Juan Kochen Rossi, Cristina Nuevo-Tapioles, Mark R. Philips

Biochem Soc Trans (2023) 51 (3): 1191–1199.

https://doi.org/10.1042/BST20221347

Published: 24 May 2023

View article titled, Differential functions of the KRAS splice variants

Articles

The function and regulation of ADP-ribosylation in the DNA damage response

Lena Duma, Ivan Ahel

Biochem Soc Trans (2023) 51 (3): 995–1008.

https://doi.org/10.1042/BST20220749

Published: 12 May 2023

View article titled, The function and regulation of ADP-ribosylation in the DNA damage response

Articles

The molecular mechanisms of human separase regulation

Jun Yu, David O. Morgan, Andreas Boland

Biochem Soc Trans (2023) 51 (3): 1225–1233.

https://doi.org/10.1042/BST20221400

Published: 04 May 2023

View article titled, The molecular mechanisms of human separase regulation

Articles

Redox-regulated chaperones in cell stress responses

Kathrin Ulrich

Biochem Soc Trans (2023) 51 (3): 1169–1177.

https://doi.org/10.1042/BST20221304

Published: 04 May 2023

View article titled, Redox-regulated chaperones in cell stress responses

Articles

The multiple ubiquitination mechanisms in CFTR peripheral quality control

Shogo Taniguchi, Ryosuke Fukuda, Tsukasa Okiyoneda

Biochem Soc Trans (2023) 51 (3): 1297–1306.

https://doi.org/10.1042/BST20221468

Published: 04 May 2023

View article titled, The multiple ubiquitination mechanisms in CFTR peripheral quality control

Articles

Effectors and effects of arginine methylation

Yalong Wang, Mark T. Bedford

Biochem Soc Trans (2023) 51 (2): 725–734.

https://doi.org/10.1042/BST20221147

Published: 04 April 2023

View article titled, Effectors and effects of arginine methylation

Articles

Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Zhengyuan Huang, Pei F. Lai, Alexander T. H. Cocker, Stuart M. Haslam, Anne Dell, Hugh J. M. Brady, Mark R. Johnson

Biochem Soc Trans (2023) 51 (2): 639–653.

https://doi.org/10.1042/BST20221406

Published: 16 March 2023

View article titled, Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Articles

Mitochondrial dynamics in macrophages: divide to conquer or unite to survive?

Syeda Farhana Afroz, Karoline D. Raven, Grace M.E.P. Lawrence, Ronan Kapetanovic, Kate Schroder, Matthew J. Sweet

Biochem Soc Trans (2023) 51 (1): 41–56.

https://doi.org/10.1042/BST20220014

Published: 23 February 2023

View article titled, Mitochondrial dynamics in macrophages: divide to conquer or unite to survive?

Articles

Structural insights on the KMT2–NCP interaction

Zi Yang, Robert Zepeda, Yali Dou

Biochem Soc Trans (2023) 51 (1): 427–434.

https://doi.org/10.1042/BST20221155

Published: 25 January 2023

View article titled, Structural insights on the KMT2–NCP interaction

Articles

The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder

Katerina Cermakova, Vaclav Veverka, H. Courtney Hodges

Biochem Soc Trans (2023) 51 (1): 125–135.

https://doi.org/10.1042/BST20220342

Published: 18 January 2023

View article titled, The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder

Articles

From seeds to trees: how E2 enzymes grow ubiquitin chains

Adam J. Middleton, Catherine L. Day

Biochem Soc Trans (2023) 51 (1): 353–362.

https://doi.org/10.1042/BST20220880

Published: 16 January 2023

View article titled, From seeds to trees: how E2 enzymes grow ubiquitin chains

Articles

The role of post-translational modifications in synaptic AMPA receptor activity

Elisa Corti, Carlos B. Duarte

Biochem Soc Trans (2023) 51 (1): 315–330.

https://doi.org/10.1042/BST20220827

Published: 11 January 2023

View article titled, The role of post-translational modifications in synaptic AMPA receptor activity

Articles

The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer

Aristeidis Panagiotis Sfakianos, Rebecca Mallory Raven, Anne Elizabeth Willis

Biochem Soc Trans (2022) 50 (6): 1885–1895.

https://doi.org/10.1042/BST20221035

Published: 13 December 2022

View article titled, The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer

Articles

Functional regulation of Wnt protein through post-translational modifications

Jia Yu, David M. Virshup

Biochem Soc Trans (2022) 50 (6): 1797–1808.

https://doi.org/10.1042/BST20220735

Published: 09 December 2022

View article titled, Functional regulation of Wnt protein through post-translational modifications

Articles

Activities and binding partners of E3 ubiquitin ligase DTX3L and its roles in cancer

Carlos Vela-Rodríguez, Lari Lehtiö

Biochem Soc Trans (2022) 50 (6): 1683–1692.

https://doi.org/10.1042/BST20220501

Published: 24 November 2022

View article titled, Activities and binding partners of E3 ubiquitin ligase DTX3L and its roles in cancer

Articles

ISG15 driven cellular responses to virus infection

Deeksha Munnur, Adrianna Banducci-Karp, Sumana Sanyal

Biochem Soc Trans (2022) 50 (6): 1837–1846.

https://doi.org/10.1042/BST20220839

Published: 23 November 2022

View article titled, ISG15 driven cellular responses to virus infection

Articles

Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt

Neha Mani, Rie Nygaard, Filippo Mancia

Biochem Soc Trans (2022) 50 (6): 1763–1772.

https://doi.org/10.1042/BST20220634

Published: 23 November 2022

View article titled, Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt

Articles

The functional importance of VCP to maintaining cellular protein homeostasis

Brittany A. Ahlstedt, Rakesh Ganji, Malavika Raman

Biochem Soc Trans (2022) 50 (5): 1457–1469.

https://doi.org/10.1042/BST20220648

Published: 05 October 2022

View article titled, The functional importance of VCP to maintaining cellular protein homeostasis

Articles

Regulation of ATR–CHK1 signaling by ubiquitination of CLASPIN

Xuefei Zhu, Xiang-Yang Zheng, Peng Gong, Xingzhi Xu

Biochem Soc Trans (2022) 50 (5): 1471–1480.

https://doi.org/10.1042/BST20220729

Published: 05 October 2022

View article titled, Regulation of ATR–CHK1 signaling by ubiquitination of CLASPIN

Articles

Sometimes less is more: inhibitory infrared light during early reperfusion calms hyperactive mitochondria and suppresses reperfusion injury

Paul T. Morse, Junmei Wan, Jamie Bell, Icksoo Lee, Dennis J. Goebel, Moh H. Malek, Thomas H. Sanderson, Maik Hüttemann

Biochem Soc Trans (2022) 50 (5): 1377–1388.

https://doi.org/10.1042/BST20220446

Published: 06 September 2022

View article titled, Sometimes less is more: inhibitory infrared light during early reperfusion calms hyperactive mitochondria and suppresses reperfusion injury

Articles

CDKL5 deficiency disorder: molecular insights and mechanisms of pathogenicity to fast-track therapeutic development

Nicole J. Van Bergen, Sean Massey, Anita Quigley, Ben Rollo, Alexander R. Harris, Robert M.I. Kapsa, John Christodoulou

Biochem Soc Trans (2022) 50 (4): 1207–1224.

https://doi.org/10.1042/BST20220791

Published: 23 August 2022

View article titled, CDKL5 deficiency disorder: molecular insights and mechanisms of pathogenicity to fast-track therapeutic development

Articles

Linear ubiquitination in immune and neurodegenerative diseases, and beyond

In Collection

Cell death and survival

Fuminori Tokunaga, Fumiyo Ikeda

Biochem Soc Trans (2022) 50 (2): 799–811.

https://doi.org/10.1042/BST20211078

Published: 28 March 2022

View article titled, Linear ubiquitination in immune and neurodegenerative diseases, and beyond

Articles

GCN2: roles in tumour development and progression

Lyssa T. Gold, Glenn R. Masson

Biochem Soc Trans (2022) 50 (2): 737–745.

https://doi.org/10.1042/BST20211252

Published: 21 March 2022

View article titled, GCN2: roles in tumour development and progression

Articles

IMPDH dysregulation in disease: a mini review

Anika L. Burrell, Justin M. Kollman

Biochem Soc Trans (2022) 50 (1): 71–82.

https://doi.org/10.1042/BST20210446

Published: 22 February 2022

View article titled, IMPDH dysregulation in disease: a mini review

Articles

A proteomic perspective on TNF-mediated signalling and cell death

In Collection

Cell death and survival

Maria C. Tanzer

Biochem Soc Trans (2022) 50 (1): 13–20.

https://doi.org/10.1042/BST20211114

Published: 15 February 2022

View article titled, A proteomic perspective on TNF-mediated signalling and cell death

Articles

The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation

Daria Sicari, Janine Weber, Elena Maspero, Simona Polo

Biochem Soc Trans (2022) 50 (1): 473–485.

https://doi.org/10.1042/BST20210731

Published: 07 February 2022

View article titled, The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation

Articles

Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Jorge Ripoll-Rozada, Joshua W. C. Maxwell, Richard J. Payne, Pedro José Barbosa Pereira

Biochem Soc Trans (2022) 50 (1): 387–401.

https://doi.org/10.1042/BST20210600

Published: 07 January 2022

View article titled, Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Articles

Exploring the multifunctionality of SR proteins

Irena Slišković, Hannah Eich, Michaela Müller-McNicoll

Biochem Soc Trans (2022) 50 (1): 187–198.

https://doi.org/10.1042/BST20210325

Published: 23 December 2021

View article titled, Exploring the multifunctionality of SR proteins

Articles

PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

In Collection

Cell death and survival

Chloe M. McKee, Fabian A. Fischer, Jelena S. Bezbradica, Rebecca C. Coll

Biochem Soc Trans (2021) 49 (6): 2495–2507.

https://doi.org/10.1042/BST20200987

Published: 02 December 2021

View article titled, PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

Articles

The role of protein acetylation in regulating mitochondrial fusion and fission

Golam M. Uddin, Rafa Abbas, Timothy E. Shutt

Biochem Soc Trans (2021) 49 (6): 2807–2819.

https://doi.org/10.1042/BST20210798

Published: 23 November 2021

View article titled, The role of protein acetylation in regulating mitochondrial fusion and fission

Articles

Writing and erasing O- GlcNAc from target proteins in cells

Yun Ge, Christina M. Woo

Biochem Soc Trans (2021) 49 (6): 2891–2901.

https://doi.org/10.1042/BST20210865

Published: 16 November 2021

View article titled, Writing and erasing O- GlcNAc from target proteins in cells

Articles

Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatin

Akhil Gargey Iragavarapu, Liqi Yao, Vignesh Kasinath

Biochem Soc Trans (2021) 49 (6): 2639–2653.

https://doi.org/10.1042/BST20210450

Published: 08 November 2021

View article titled, Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatin

Articles

Chemical biology approaches to study histone interactors

Antony J. Burton, Ghaith M. Hamza, Andrew X. Zhang, Tom W. Muir

Biochem Soc Trans (2021) 49 (5): 2431–2441.

https://doi.org/10.1042/BST20210772

Published: 28 October 2021

View article titled, Chemical biology approaches to study histone interactors

Articles

LUBAC: a new player in polyglucosan body disease

Andrew Aboujaoude, Berge Minassian, Sharmistha Mitra

Biochem Soc Trans (2021) 49 (5): 2443–2454.

https://doi.org/10.1042/BST20210838

Published: 28 October 2021

View article titled, LUBAC: a new player in polyglucosan body disease

Articles

Functional interrogation and therapeutic targeting of protein tyrosine phosphatases

Aaron D. Krabill, Zhong-Yin Zhang

Biochem Soc Trans (2021) 49 (4): 1723–1734.

https://doi.org/10.1042/BST20201308

Published: 25 August 2021

View article titled, Functional interrogation and therapeutic targeting of protein tyrosine phosphatases

Articles

Integrated mass spectrometry-based multi-omics for elucidating mechanisms of bacterial virulence

Lok Man, William P. Klare, Ashleigh L. Dale, Joel A. Cain, Stuart J. Cordwell

Biochem Soc Trans (2021) 49 (5): 1905–1926.

https://doi.org/10.1042/BST20191088

Published: 10 August 2021

View article titled, Integrated mass spectrometry-based multi-omics for elucidating mechanisms of bacterial virulence

Articles

Host ADP-ribosylation and the SARS-CoV-2 macrodomain

Nicolas C. Hoch

Biochem Soc Trans (2021) 49 (4): 1711–1721.

https://doi.org/10.1042/BST20201212

Published: 05 August 2021

View article titled, Host ADP-ribosylation and the SARS-CoV-2 macrodomain

Articles

The Hitchhiker's guide to glycoproteomics

Tiago Oliveira, Morten Thaysen-Andersen, Nicolle H. Packer, Daniel Kolarich

Biochem Soc Trans (2021) 49 (4): 1643–1662.

https://doi.org/10.1042/BST20200879

Published: 20 July 2021

View article titled, The Hitchhiker's guide to glycoproteomics

Articles

Protein Phosphatase 2A (PP2A) mutations in brain function, development, and neurologic disease

Iris Verbinnen, Pieter Vaneynde, Sara Reynhout, Lisa Lenaerts, Rita Derua, Gunnar Houge, Veerle Janssens

Biochem Soc Trans (2021) 49 (4): 1567–1588.

https://doi.org/10.1042/BST20201313

Published: 09 July 2021

View article titled, Protein Phosphatase 2A (PP2A) mutations in brain function, development, and neurologic disease

Articles

The Eyes Absent proteins in development and in developmental disorders

Upendra Kumar Soni, Kaushik Roychoudhury, Rashmi S. Hegde

Biochem Soc Trans (2021) 49 (3): 1397–1408.

https://doi.org/10.1042/BST20201302

Published: 01 July 2021

View article titled, The Eyes Absent proteins in development and in developmental disorders

Articles

Protein-fragment complementation assays for large-scale analysis of protein–protein interactions

Ewa Blaszczak, Natalia Lazarewicz, Aswani Sudevan, Robert Wysocki, Gwenaël Rabut

Biochem Soc Trans (2021) 49 (3): 1337–1348.

https://doi.org/10.1042/BST20201058

Published: 22 June 2021

View article titled, Protein-fragment complementation assays for large-scale analysis of protein–protein interactions

Articles

The HSP70 chaperone as sensor of the NEDD8 cycle upon DNA damage

Aymeric P. Bailly, Dimitris P. Xirodimas

Biochem Soc Trans (2021) 49 (3): 1075–1083.

https://doi.org/10.1042/BST20200381

Published: 22 June 2021

View article titled, The HSP70 chaperone as sensor of the NEDD8 cycle upon DNA damage

Articles

Evolutionary crossroads of cell signaling: PP1 and PP2A substrate sites in intrinsically disordered regions

Bernhard Hoermann, Maja Köhn

Biochem Soc Trans (2021) 49 (3): 1065–1074.

https://doi.org/10.1042/BST20200175

Published: 08 June 2021

View article titled, Evolutionary crossroads of cell signaling: PP1 and PP2A substrate sites in intrinsically disordered regions

Articles

Not just a writer: PRC2 as a chromatin reader

Michael Uckelmann, Chen Davidovich

Biochem Soc Trans (2021) 49 (3): 1159–1170.

https://doi.org/10.1042/BST20200728

Published: 01 June 2021

View article titled, Not just a writer: PRC2 as a chromatin reader

Email alerts

CONNECT

EXPLORE

This Feature Is Available To Subscribers Only