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Linear ubiquitination in immune and neurodegenerative diseases, and beyond

Fuminori Tokunaga, Fumiyo Ikeda

Biochem Soc Trans (2022) 50 (2): 799–811.

DOI: https://doi.org/10.1042/BST20211078

Published: 28 March 2022

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Articles

GCN2: roles in tumour development and progression

Lyssa T. Gold, Glenn R. Masson

Biochem Soc Trans (2022) 50 (2): 737–745.

DOI: https://doi.org/10.1042/BST20211252

Published: 21 March 2022

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Articles

IMPDH dysregulation in disease: a mini review

Anika L. Burrell, Justin M. Kollman

Biochem Soc Trans (2022) 50 (1): 71–82.

DOI: https://doi.org/10.1042/BST20210446

Published: 22 February 2022

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A proteomic perspective on TNF-mediated signalling and cell death

Maria C. Tanzer

Biochem Soc Trans (2022) 50 (1): 13–20.

DOI: https://doi.org/10.1042/BST20211114

Published: 15 February 2022

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The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation

Daria Sicari, Janine Weber, Elena Maspero, Simona Polo

Biochem Soc Trans (2022) 50 (1): 473–485.

DOI: https://doi.org/10.1042/BST20210731

Published: 07 February 2022

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Articles

Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Jorge Ripoll-Rozada, Joshua W. C. Maxwell, Richard J. Payne, Pedro José Barbosa Pereira

Biochem Soc Trans (2022) 50 (1): 387–401.

DOI: https://doi.org/10.1042/BST20210600

Published: 07 January 2022

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Exploring the multifunctionality of SR proteins

Irena Slišković, Hannah Eich, Michaela Müller-McNicoll

Biochem Soc Trans (2022) 50 (1): 187–198.

DOI: https://doi.org/10.1042/BST20210325

Published: 23 December 2021

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PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

Chloe M. McKee, Fabian A. Fischer, Jelena S. Bezbradica, Rebecca C. Coll

Biochem Soc Trans (2021) 49 (6): 2495–2507.

DOI: https://doi.org/10.1042/BST20200987

Published: 02 December 2021

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Articles

The role of protein acetylation in regulating mitochondrial fusion and fission

Golam M. Uddin, Rafa Abbas, Timothy E. Shutt

Biochem Soc Trans (2021) 49 (6): 2807–2819.

DOI: https://doi.org/10.1042/BST20210798

Published: 23 November 2021

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Articles

Writing and erasing O- GlcNAc from target proteins in cells

Yun Ge, Christina M. Woo

Biochem Soc Trans (2021) 49 (6): 2891–2901.

DOI: https://doi.org/10.1042/BST20210865

Published: 16 November 2021

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Articles

Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatin

Akhil Gargey Iragavarapu, Liqi Yao, Vignesh Kasinath

Biochem Soc Trans (2021) 49 (6): 2639–2653.

DOI: https://doi.org/10.1042/BST20210450

Published: 08 November 2021

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Articles

Chemical biology approaches to study histone interactors

Antony J. Burton, Ghaith M. Hamza, Andrew X. Zhang, Tom W. Muir

Biochem Soc Trans (2021) 49 (5): 2431–2441.

DOI: https://doi.org/10.1042/BST20210772

Published: 28 October 2021

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Articles

LUBAC: a new player in polyglucosan body disease

Andrew Aboujaoude, Berge Minassian, Sharmistha Mitra

Biochem Soc Trans (2021) 49 (5): 2443–2454.

DOI: https://doi.org/10.1042/BST20210838

Published: 28 October 2021

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Articles

Functional interrogation and therapeutic targeting of protein tyrosine phosphatases

Aaron D. Krabill, Zhong-Yin Zhang

Biochem Soc Trans (2021) 49 (4): 1723–1734.

DOI: https://doi.org/10.1042/BST20201308

Published: 25 August 2021

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Articles

Integrated mass spectrometry-based multi-omics for elucidating mechanisms of bacterial virulence

Lok Man, William P. Klare, Ashleigh L. Dale, Joel A. Cain, Stuart J. Cordwell

Biochem Soc Trans (2021) 49 (5): 1905–1926.

DOI: https://doi.org/10.1042/BST20191088

Published: 10 August 2021

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Articles

Host ADP-ribosylation and the SARS-CoV-2 macrodomain

Nicolas C. Hoch

Biochem Soc Trans (2021) 49 (4): 1711–1721.

DOI: https://doi.org/10.1042/BST20201212

Published: 05 August 2021

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Articles

The Hitchhiker's guide to glycoproteomics

Tiago Oliveira, Morten Thaysen-Andersen, Nicolle H. Packer, Daniel Kolarich

Biochem Soc Trans (2021) 49 (4): 1643–1662.

DOI: https://doi.org/10.1042/BST20200879

Published: 20 July 2021

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Articles

Protein Phosphatase 2A (PP2A) mutations in brain function, development, and neurologic disease

Iris Verbinnen, Pieter Vaneynde, Sara Reynhout, Lisa Lenaerts, Rita Derua, Gunnar Houge, Veerle Janssens

Biochem Soc Trans (2021) 49 (4): 1567–1588.

DOI: https://doi.org/10.1042/BST20201313

Published: 09 July 2021

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Articles

The Eyes Absent proteins in development and in developmental disorders

Upendra Kumar Soni, Kaushik Roychoudhury, Rashmi S. Hegde

Biochem Soc Trans (2021) 49 (3): 1397–1408.

DOI: https://doi.org/10.1042/BST20201302

Published: 01 July 2021

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Articles

Protein-fragment complementation assays for large-scale analysis of protein–protein interactions

Ewa Blaszczak, Natalia Lazarewicz, Aswani Sudevan, Robert Wysocki, Gwenaël Rabut

Biochem Soc Trans (2021) 49 (3): 1337–1348.

DOI: https://doi.org/10.1042/BST20201058

Published: 22 June 2021

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Articles

The HSP70 chaperone as sensor of the NEDD8 cycle upon DNA damage

Aymeric P. Bailly, Dimitris P. Xirodimas

Biochem Soc Trans (2021) 49 (3): 1075–1083.

DOI: https://doi.org/10.1042/BST20200381

Published: 22 June 2021

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Articles

Evolutionary crossroads of cell signaling: PP1 and PP2A substrate sites in intrinsically disordered regions

Bernhard Hoermann, Maja Köhn

Biochem Soc Trans (2021) 49 (3): 1065–1074.

DOI: https://doi.org/10.1042/BST20200175

Published: 08 June 2021

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Articles

Not just a writer: PRC2 as a chromatin reader

Michael Uckelmann, Chen Davidovich

Biochem Soc Trans (2021) 49 (3): 1159–1170.

DOI: https://doi.org/10.1042/BST20200728

Published: 01 June 2021

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Articles

Transcription factors regulated by cAMP in smooth muscle of the myometrium at human parturition

Jonathan K.H. Li, Pei F. Lai, Rachel M. Tribe, Mark R. Johnson

Biochem Soc Trans (2021) 49 (2): 997–1011.

DOI: https://doi.org/10.1042/BST20201173

Published: 16 April 2021

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Articles

Chemical reporters to study mammalian O-glycosylation

Kathryn E. Huxley, Lianne I. Willems

Biochem Soc Trans (2021) 49 (2): 903–913.

DOI: https://doi.org/10.1042/BST20200839

Published: 16 April 2021

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Articles

Regulation of MST complexes and activity via SARAH domain modifications

Sofiia Karchugina, Dorothy Benton, Jonathan Chernoff

Biochem Soc Trans (2021) 49 (2): 675–683.

DOI: https://doi.org/10.1042/BST20200559

Published: 16 April 2021

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Articles

Allosteric regulation of histone lysine methyltransferases: from context-specific regulation to selective drugs

Chen Davidovich, Qi Zhang

Biochem Soc Trans (2021) 49 (2): 591–607.

DOI: https://doi.org/10.1042/BST20200238

Published: 26 March 2021

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Articles

Nutrient regulation of the flow of genetic information by O-GlcNAcylation

Yi Zhu, Gerald W. Hart

Biochem Soc Trans (2021) 49 (2): 867–880.

DOI: https://doi.org/10.1042/BST20200769

Published: 26 March 2021

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Articles

Proteasome in action: substrate degradation by the 26S proteasome

Indrajit Sahu, Michael H. Glickman

Biochem Soc Trans (2021) 49 (2): 629–644.

DOI: https://doi.org/10.1042/BST20200382

Published: 17 March 2021

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Articles

Glycoengineering Chinese hamster ovary cells: a short history

Roberto Donini, Stuart M. Haslam, Cleo Kontoravdi

Biochem Soc Trans (2021) 49 (2): 915–931.

DOI: https://doi.org/10.1042/BST20200840

Published: 11 March 2021

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Articles

Plant asparaginyl endopeptidases and their structural determinants of function

Samuel G. Nonis, Joel Haywood, Joshua S. Mylne

Biochem Soc Trans (2021) 49 (2): 965–976.

DOI: https://doi.org/10.1042/BST20200908

Published: 05 March 2021

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Articles

It's not just a phase; ubiquitination in cytosolic protein quality control

Heather A. Baker, Jonathan P. Bernardini

Biochem Soc Trans (2021) 49 (1): 365–377.

DOI: https://doi.org/10.1042/BST20200694

Published: 26 February 2021

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Articles

The molecular basis of plant cellulose synthase complex organisation and assembly

Thomas H Wilson, Manoj Kumar, Simon R Turner

Biochem Soc Trans (2021) 49 (1): 379–391.

DOI: https://doi.org/10.1042/BST20200697

Published: 22 February 2021

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Articles

Using computational modelling to reveal mechanisms of epigenetic Polycomb control

Cecilia Lövkvist, Martin Howard

Biochem Soc Trans (2021) 49 (1): 71–77.

DOI: https://doi.org/10.1042/BST20190955

Published: 22 February 2021

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Articles

The ERK mitogen-activated protein kinase signaling network: the final frontier in RAS signal transduction

Jennifer E. Klomp, Jeff A. Klomp, Channing J. Der

Biochem Soc Trans (2021) 49 (1): 253–267.

DOI: https://doi.org/10.1042/BST20200507

Published: 05 February 2021

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Articles

Towards structure-focused glycoproteomics

Anastasia Chernykh, Rebeca Kawahara, Morten Thaysen-Andersen

Biochem Soc Trans (2021) 49 (1): 161–186.

DOI: https://doi.org/10.1042/BST20200222

Published: 13 January 2021

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Articles

Combinatorial biosynthesis for the generation of new-to-nature peptide antimicrobials

Fleur Ruijne, Oscar P. Kuipers

Biochem Soc Trans (2021) 49 (1): 203–215.

DOI: https://doi.org/10.1042/BST20200425

Published: 13 January 2021

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Articles

Inhibition of RAF dimers: it takes two to tango

Frazer A. Cook, Simon J. Cook

Biochem Soc Trans (2021) 49 (1): 237–251.

DOI: https://doi.org/10.1042/BST20200485

Published: 24 December 2020

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Articles

The impact of photorespiration on plant primary metabolism through metabolic and redox regulation

Stefan Timm

Biochem Soc Trans (2020) 48 (6): 2495–2504.

DOI: https://doi.org/10.1042/BST20200055

Published: 10 December 2020

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Articles

The complexity of PRC2 catalysts CLF and SWN in plants

Jie Shu, Chen Chen, Chenlong Li, Yuhai Cui

Biochem Soc Trans (2020) 48 (6): 2779–2789.

DOI: https://doi.org/10.1042/BST20200660

Published: 10 November 2020

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Articles

Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases

Filippo Fiorentini, Diego Esposito, Katrin Rittinger

Biochem Soc Trans (2020) 48 (6): 2615–2624.

DOI: https://doi.org/10.1042/BST20200383

Published: 10 November 2020

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Includes: Supplementary data

Articles

Protein phosphatase-1: dual activity regulation by Inhibitor-2

Sarah Lemaire, Mathieu Bollen

Biochem Soc Trans (2020) 48 (5): 2229–2240.

DOI: https://doi.org/10.1042/BST20200503

Published: 14 October 2020

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Articles

Biosynthesis of lanthionine-constrained agonists of G protein-coupled receptors

Gert N. Moll, Anneke Kuipers, Rick Rink, Tjibbe Bosma, Louwe de Vries, Pawel Namsolleck

Biochem Soc Trans (2020) 48 (5): 2195–2203.

DOI: https://doi.org/10.1042/BST20200427

Published: 14 October 2020

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Articles

Effects of carboxyl-terminal methylation on holoenzyme function of the PP2A subfamily

Isha Nasa, Arminja N. Kettenbach

Biochem Soc Trans (2020) 48 (5): 2015–2027.

DOI: https://doi.org/10.1042/BST20200177

Published: 14 October 2020

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Articles

Human 2-oxoglutarate-dependent oxygenases: nutrient sensors, stress responders, and disease mediators

Sally C. Fletcher, Mathew L. Coleman

Biochem Soc Trans (2020) 48 (5): 1843–1858.

DOI: https://doi.org/10.1042/BST20190333

Published: 28 September 2020

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Articles

Smc5/6, an atypical SMC complex with two RING-type subunits

Roger Solé-Soler, Jordi Torres-Rosell

Biochem Soc Trans (2020) 48 (5): 2159–2171.

DOI: https://doi.org/10.1042/BST20200389

Published: 23 September 2020

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Articles

Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for…

Simon J. Cook, Julie A. Tucker, Pamela A. Lochhead

Biochem Soc Trans (2020) 48 (5): 1859–1875.

DOI: https://doi.org/10.1042/BST20190338

Published: 11 September 2020

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Articles

Molecular mechanisms mediating asymmetric subcellular localisation of the core planar polarity pathway proteins

Carl Harrison, Hongyu Shao, Helen Strutt, David Strutt

Biochem Soc Trans (2020) 48 (4): 1297–1308.

DOI: https://doi.org/10.1042/BST20190404

Published: 21 August 2020

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Articles

The evolutionary dynamics of venom toxins made by insects and other animals

Andrew A. Walker

Biochem Soc Trans (2020) 48 (4): 1353–1365.

DOI: https://doi.org/10.1042/BST20190820

Published: 05 August 2020

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Articles

The mitochondrial ADP/ATP carrier exists and functions as a monomer

Edmund R.S. Kunji, Jonathan J. Ruprecht

Biochem Soc Trans (2020) 48 (4): 1419–1432.

DOI: https://doi.org/10.1042/BST20190933

Published: 29 July 2020

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