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Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM

Florian Fäßler, Manjunath G. Javoor, Florian KM Schur

Biochem Soc Trans (2023) BST20220221.

DOI: https://doi.org/10.1042/BST20220221

Published: 25 January 2023

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The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder

Katerina Cermakova, Vaclav Veverka, H. Courtney Hodges

Biochem Soc Trans (2023) BST20220342.

DOI: https://doi.org/10.1042/BST20220342

Published: 18 January 2023

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From seeds to trees: how E2 enzymes grow ubiquitin chains

Adam J. Middleton, Catherine L. Day

Biochem Soc Trans (2023) BST20220880.

DOI: https://doi.org/10.1042/BST20220880

Published: 16 January 2023

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The dynamic balance of the skin microbiome across the lifespan

Elizabeth C. Townsend, Lindsay R. Kalan

Biochem Soc Trans (2023) BST20220216.

DOI: https://doi.org/10.1042/BST20220216

Published: 06 January 2023

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Interactions governing transcriptional activity of nuclear receptors

Sabab Hasan Khan, C. Denise Okafor

Biochem Soc Trans (2022) 50 (6): 1941–1952.

DOI: https://doi.org/10.1042/BST20220338

Published: 16 December 2022

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The mechanisms of chromogranin B-regulated Cl − homeostasis

Qiu-Xing Jiang, Gaya Yadav

Biochem Soc Trans (2022) 50 (6): 1659–1672.

DOI: https://doi.org/10.1042/BST20220435

Published: 13 December 2022

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Placental extracellular vesicles in maternal-fetal communication during pregnancy

Charlène Martin, Mathilde Bergamelli, Cécile E. Malnou, Gisela D'Angelo

Biochem Soc Trans (2022) 50 (6): 1785–1795.

DOI: https://doi.org/10.1042/BST20220734

Published: 09 December 2022

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Deciphering the mechanism and function of Hsp100 unfoldases from protein structure

Grace Lee, Rebecca S. Kim, Sang Bum Lee, Sukyeong Lee, Francis T.F. Tsai

Biochem Soc Trans (2022) 50 (6): 1725–1736.

DOI: https://doi.org/10.1042/BST20220590

Published: 01 December 2022

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The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI

Dmitry Lyumkis, Nancy C. Horton

Biochem Soc Trans (2022) 50 (6): 1703–1714.

DOI: https://doi.org/10.1042/BST20220547

Published: 18 November 2022

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The role of UV-DDB in processing 8-oxoguanine during base excision repair

Ashna Nagpal, Sripriya Raja, Bennett Van Houten

Biochem Soc Trans (2022) 50 (5): 1481–1488.

DOI: https://doi.org/10.1042/BST20220748

Published: 28 October 2022

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A comprehensive review of methods to study lncRNA–protein interactions in solution

Maulik D. Badmalia, Higor Sette Pereira, M. Quadir Siddiqui, Trushar R. Patel

Biochem Soc Trans (2022) 50 (5): 1415–1426.

DOI: https://doi.org/10.1042/BST20220604

Published: 17 October 2022

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Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT

Theresa M. Smith, Barry M. Willardson

Biochem Soc Trans (2022) 50 (5): 1403–1414.

DOI: https://doi.org/10.1042/BST20220591

Published: 05 October 2022

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Protective HLA-B57: T cell and natural killer cell recognition in HIV infection

Christian A. Lobos, Jonathan Downing, Lloyd J. D'Orsogna, Demetra S.M. Chatzileontiadou, Stephanie Gras

Biochem Soc Trans (2022) 50 (5): 1329–1339.

DOI: https://doi.org/10.1042/BST20220244

Published: 16 September 2022

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The role of RHIM in necroptosis

Theresa Riebeling, Ulrich Kunzendorf, Stefan Krautwald

Biochem Soc Trans (2022) 50 (4): 1197–1205.

DOI: https://doi.org/10.1042/BST20220535

Published: 30 August 2022

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LILBID-MS: using lasers to shed light on biomolecular architectures

Nils Hellwig, Janosch Martin, Nina Morgner

Biochem Soc Trans (2022) 50 (3): 1057–1067.

DOI: https://doi.org/10.1042/BST20190881

Published: 13 June 2022

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CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact

Takahiro Ishizaki, Sophia Hernandez, Martina S. Paoletta, Theo Sanderson, Ellen S.C. Bushell

Biochem Soc Trans (2022) 50 (3): 1069–1079.

DOI: https://doi.org/10.1042/BST20210281

Published: 27 May 2022

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AAA+ proteins: one motor, multiple ways to work

JiaBei Lin, James Shorter, Aaron L. Lucius

Biochem Soc Trans (2022) 50 (2): 895–906.

DOI: https://doi.org/10.1042/BST20200350

Published: 31 March 2022

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MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Steven R. Van Doren

Biochem Soc Trans (2022) 50 (2): 839–851.

DOI: https://doi.org/10.1042/BST20210640

Published: 28 March 2022

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PIDD1 in cell cycle control, sterile inflammation and cell death

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Cell death and survival

Elias S. Weiler, Tamas G. Szabo, Irmina Garcia-Carpio, Andreas Villunger

Biochem Soc Trans (2022) 50 (2): 813–824.

DOI: https://doi.org/10.1042/BST20211186

Published: 28 March 2022

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Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?

Ekaterina Shevchenko, Tatu Pantsar

Biochem Soc Trans (2022) 50 (1): 633–648.

DOI: https://doi.org/10.1042/BST20210837

Published: 28 February 2022

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Articles

Exploring cryo-electron microscopy with molecular dynamics

John W. Vant, Daipayan Sarkar, Jonathan Nguyen, Alexander T. Baker, Josh V. Vermaas, Abhishek Singharoy

Biochem Soc Trans (2022) 50 (1): 569–581.

DOI: https://doi.org/10.1042/BST20210485

Published: 25 February 2022

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IMPDH dysregulation in disease: a mini review

Anika L. Burrell, Justin M. Kollman

Biochem Soc Trans (2022) 50 (1): 71–82.

DOI: https://doi.org/10.1042/BST20210446

Published: 22 February 2022

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Control of non-productive RNA polymerase II transcription via its early termination in metazoans

Jérôme O. Rouvière, Søren Lykke-Andersen, Torben Heick Jensen

Biochem Soc Trans (2022) 50 (1): 283–295.

DOI: https://doi.org/10.1042/BST20201140

Published: 15 February 2022

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Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin

Luke T. Marr, Prasoon Jaya, Laxmi N. Mishra, Jeffrey J. Hayes

Biochem Soc Trans (2022) 50 (1): 199–212.

DOI: https://doi.org/10.1042/BST20210959

Published: 15 February 2022

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Inferiority complex: why do sensory ion channels multimerize?

Nikita Gamper, Shihab Shah

Biochem Soc Trans (2022) 50 (1): 213–222.

DOI: https://doi.org/10.1042/BST20211002

Published: 15 February 2022

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Multiple roles of Pol epsilon in eukaryotic chromosome replication

Milos A. Cvetkovic, Esther Ortega, Roberto Bellelli, Alessandro Costa

Biochem Soc Trans (2022) 50 (1): 309–320.

DOI: https://doi.org/10.1042/BST20210082

Published: 07 February 2022

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Mechanism of action of nucleotide excision repair machinery

Areetha D'Souza, Alexandra M. Blee, Walter J. Chazin

Biochem Soc Trans (2022) 50 (1): 375–386.

DOI: https://doi.org/10.1042/BST20210246

Published: 25 January 2022

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Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)

Jai Woo Lee, Miguel A. Maria-Solano, Thi Ngoc Lan Vu, Sanghee Yoon, Sun Choi

Biochem Soc Trans (2022) 50 (1): 241–252.

DOI: https://doi.org/10.1042/BST20211240

Published: 25 January 2022

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Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Matthew J. A. Hein, Marc Kvansakul, Fung T. Lay, Thanh Kha Phan, Mark D. Hulett

Biochem Soc Trans (2022) 50 (1): 423–437.

DOI: https://doi.org/10.1042/BST20200884

Published: 11 January 2022

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Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Jorge Ripoll-Rozada, Joshua W. C. Maxwell, Richard J. Payne, Pedro José Barbosa Pereira

Biochem Soc Trans (2022) 50 (1): 387–401.

DOI: https://doi.org/10.1042/BST20210600

Published: 07 January 2022

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The role of caspases as executioners of apoptosis

Sharad Kumar, Loretta Dorstyn, Yoon Lim

Biochem Soc Trans (2022) 50 (1): 33–45.

DOI: https://doi.org/10.1042/BST20210751

Published: 23 December 2021

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HSP90 as a regulator of extracellular matrix dynamics

Abir Chakraborty, Adrienne Lesley Edkins

Biochem Soc Trans (2021) 49 (6): 2611–2625.

DOI: https://doi.org/10.1042/BST20210374

Published: 16 December 2021

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VDAC2 and the BCL-2 family of proteins

Zheng Yuan, Grant Dewson, Peter E. Czabotar, Richard W. Birkinshaw

Biochem Soc Trans (2021) 49 (6): 2787–2795.

DOI: https://doi.org/10.1042/BST20210753

Published: 16 December 2021

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How a cell decides its own fate: a single-cell view of molecular mechanisms and dynamics of cell-type specification

Maria Mircea, Stefan Semrau

Biochem Soc Trans (2021) 49 (6): 2509–2525.

DOI: https://doi.org/10.1042/BST20210135

Published: 02 December 2021

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Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation

David M. Wood, Renwick C.J. Dobson, Christopher R. Horne

Biochem Soc Trans (2021) 49 (6): 2711–2726.

DOI: https://doi.org/10.1042/BST20210674

Published: 02 December 2021

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Pluripotency transcription factors at the focus: the phase separation paradigm in stem cells

Camila Oses, Martin Stortz, Paula Verneri, Alejandra Guberman, Valeria Levi

Biochem Soc Trans (2021) 49 (6): 2871–2878.

DOI: https://doi.org/10.1042/BST20210856

Published: 23 November 2021

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Live-cell visualization of cytochrome c : a tool to explore apoptosis

João Pessoa

Biochem Soc Trans (2021) 49 (6): 2903–2915.

DOI: https://doi.org/10.1042/BST20211028

Published: 08 November 2021

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Articles

TOP2B's contributions to transcription

Caroline A. Austin, Ian G. Cowell, Mushtaq M. Khazeem, Dawn Lok, Huei Teng Ng

Biochem Soc Trans (2021) 49 (6): 2483–2493.

DOI: https://doi.org/10.1042/BST20200454

Published: 08 November 2021

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LUBAC: a new player in polyglucosan body disease

Andrew Aboujaoude, Berge Minassian, Sharmistha Mitra

Biochem Soc Trans (2021) 49 (5): 2443–2454.

DOI: https://doi.org/10.1042/BST20210838

Published: 28 October 2021

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To export, or not to export: how nuclear export factor variants resolve Piwi's dilemma

Sheng Wang, Xiaohua Lu, Ding Qiu, Yang Yu

Biochem Soc Trans (2021) 49 (5): 2073–2079.

DOI: https://doi.org/10.1042/BST20201171

Published: 13 October 2021

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Biophysical characterisation of SMALPs

Stephanie A. Nestorow, Tim R. Dafforn, Verna Frasca

Biochem Soc Trans (2021) 49 (5): 2037–2050.

DOI: https://doi.org/10.1042/BST20201088

Published: 13 October 2021

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Targeting small GTPases and their downstream pathways with intracellular macromolecule binders to define alternative therapeutic strategies in cancer

Marie Sorbara, Nicolas Bery

Biochem Soc Trans (2021) 49 (5): 2021–2035.

DOI: https://doi.org/10.1042/BST20201059

Published: 08 October 2021

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An integrated view of innate immune mechanisms in C. elegans

Benjamin W. Harding, Jonathan J. Ewbank

Biochem Soc Trans (2021) 49 (5): 2307–2317.

DOI: https://doi.org/10.1042/BST20210399

Published: 08 October 2021

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How activated NLRs induce anti-microbial defenses in plants

Farid El Kasmi

Biochem Soc Trans (2021) 49 (5): 2177–2188.

DOI: https://doi.org/10.1042/BST20210242

Published: 08 October 2021

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Our evolving understanding of the role of the γδ T cell receptor in γδ T cell mediated immunity

Benjamin S. Gully, Jamie Rossjohn, Martin S. Davey

Biochem Soc Trans (2021) 49 (5): 1985–1995.

DOI: https://doi.org/10.1042/BST20200890

Published: 13 September 2021

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Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer

In Collection

Cell death and survival

Erinna F. Lee, W. Douglas Fairlie

Biochem Soc Trans (2021) 49 (5): 2381–2395.

DOI: https://doi.org/10.1042/BST20210749

Published: 13 September 2021

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The role of pro-domains in human growth factors and cytokines

Matthew Ratcliff, Richard Xu Zhou, Lutz Jermutus, Marko Hyvönen

Biochem Soc Trans (2021) 49 (5): 1963–1973.

DOI: https://doi.org/10.1042/BST20200663

Published: 08 September 2021

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Post-translational modifications and stabilization of microtubules regulate transport of viral factors during infections

Silvia Requena, Francisco Sánchez-Madrid, Noa B. Martín-Cófreces

Biochem Soc Trans (2021) 49 (4): 1735–1748.

DOI: https://doi.org/10.1042/BST20210017

Published: 26 August 2021

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Profiling novel pharmacology of receptor complexes using Receptor-HIT

Elizabeth K.M. Johnstone, Kevin D.G. Pfleger

Biochem Soc Trans (2021) 49 (4): 1555–1565.

DOI: https://doi.org/10.1042/BST20201110

Published: 26 August 2021

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The influence of lipid digestion on the fate of orally administered drug delivery vehicles

Ben J. Boyd, Andrew J. Clulow

Biochem Soc Trans (2021) 49 (4): 1749–1761.

DOI: https://doi.org/10.1042/BST20210168

Published: 25 August 2021

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