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LILBID-MS: using lasers to shed light on biomolecular architectures

Nils Hellwig, Janosch Martin, Nina Morgner

Biochem Soc Trans (2022) 50 (3): 1057–1067.

DOI: https://doi.org/10.1042/BST20190881

Published: 13 June 2022

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Articles

CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact

Takahiro Ishizaki, Sophia Hernandez, Martina S. Paoletta, Theo Sanderson, Ellen S.C. Bushell

Biochem Soc Trans (2022) 50 (3): 1069–1079.

DOI: https://doi.org/10.1042/BST20210281

Published: 27 May 2022

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Articles

AAA+ proteins: one motor, multiple ways to work

JiaBei Lin, James Shorter, Aaron L. Lucius

Biochem Soc Trans (2022) 50 (2): 895–906.

DOI: https://doi.org/10.1042/BST20200350

Published: 31 March 2022

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MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Steven R. Van Doren

Biochem Soc Trans (2022) 50 (2): 839–851.

DOI: https://doi.org/10.1042/BST20210640

Published: 28 March 2022

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Articles

PIDD1 in cell cycle control, sterile inflammation and cell death

Elias S. Weiler, Tamas G. Szabo, Irmina Garcia-Carpio, Andreas Villunger

Biochem Soc Trans (2022) 50 (2): 813–824.

DOI: https://doi.org/10.1042/BST20211186

Published: 28 March 2022

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Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?

Ekaterina Shevchenko, Tatu Pantsar

Biochem Soc Trans (2022) 50 (1): 633–648.

DOI: https://doi.org/10.1042/BST20210837

Published: 28 February 2022

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Articles

Exploring cryo-electron microscopy with molecular dynamics

John W. Vant, Daipayan Sarkar, Jonathan Nguyen, Alexander T. Baker, Josh V. Vermaas, Abhishek Singharoy

Biochem Soc Trans (2022) 50 (1): 569–581.

DOI: https://doi.org/10.1042/BST20210485

Published: 25 February 2022

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Articles

IMPDH dysregulation in disease: a mini review

Anika L. Burrell, Justin M. Kollman

Biochem Soc Trans (2022) 50 (1): 71–82.

DOI: https://doi.org/10.1042/BST20210446

Published: 22 February 2022

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Articles

Control of non-productive RNA polymerase II transcription via its early termination in metazoans

Jérôme O. Rouvière, Søren Lykke-Andersen, Torben Heick Jensen

Biochem Soc Trans (2022) 50 (1): 283–295.

DOI: https://doi.org/10.1042/BST20201140

Published: 15 February 2022

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Articles

Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin

Luke T. Marr, Prasoon Jaya, Laxmi N. Mishra, Jeffrey J. Hayes

Biochem Soc Trans (2022) 50 (1): 199–212.

DOI: https://doi.org/10.1042/BST20210959

Published: 15 February 2022

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Inferiority complex: why do sensory ion channels multimerize?

Nikita Gamper, Shihab Shah

Biochem Soc Trans (2022) 50 (1): 213–222.

DOI: https://doi.org/10.1042/BST20211002

Published: 15 February 2022

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Articles

Multiple roles of Pol epsilon in eukaryotic chromosome replication

Milos A. Cvetkovic, Esther Ortega, Roberto Bellelli, Alessandro Costa

Biochem Soc Trans (2022) 50 (1): 309–320.

DOI: https://doi.org/10.1042/BST20210082

Published: 07 February 2022

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Articles

Mechanism of action of nucleotide excision repair machinery

Areetha D'Souza, Alexandra M. Blee, Walter J. Chazin

Biochem Soc Trans (2022) 50 (1): 375–386.

DOI: https://doi.org/10.1042/BST20210246

Published: 25 January 2022

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Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)

Jai Woo Lee, Miguel A. Maria-Solano, Thi Ngoc Lan Vu, Sanghee Yoon, Sun Choi

Biochem Soc Trans (2022) 50 (1): 241–252.

DOI: https://doi.org/10.1042/BST20211240

Published: 25 January 2022

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Articles

Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Matthew J. A. Hein, Marc Kvansakul, Fung T. Lay, Thanh Kha Phan, Mark D. Hulett

Biochem Soc Trans (2022) 50 (1): 423–437.

DOI: https://doi.org/10.1042/BST20200884

Published: 11 January 2022

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Articles

Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Jorge Ripoll-Rozada, Joshua W. C. Maxwell, Richard J. Payne, Pedro José Barbosa Pereira

Biochem Soc Trans (2022) 50 (1): 387–401.

DOI: https://doi.org/10.1042/BST20210600

Published: 07 January 2022

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Articles

The role of caspases as executioners of apoptosis

Sharad Kumar, Loretta Dorstyn, Yoon Lim

Biochem Soc Trans (2022) 50 (1): 33–45.

DOI: https://doi.org/10.1042/BST20210751

Published: 23 December 2021

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Articles

VDAC2 and the BCL-2 family of proteins

Zheng Yuan, Grant Dewson, Peter E. Czabotar, Richard W. Birkinshaw

Biochem Soc Trans (2021) 49 (6): 2787–2795.

DOI: https://doi.org/10.1042/BST20210753

Published: 16 December 2021

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Articles

HSP90 as a regulator of extracellular matrix dynamics

Abir Chakraborty, Adrienne Lesley Edkins

Biochem Soc Trans (2021) 49 (6): 2611–2625.

DOI: https://doi.org/10.1042/BST20210374

Published: 16 December 2021

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Articles

How a cell decides its own fate: a single-cell view of molecular mechanisms and dynamics of cell-type specification

Maria Mircea, Stefan Semrau

Biochem Soc Trans (2021) 49 (6): 2509–2525.

DOI: https://doi.org/10.1042/BST20210135

Published: 02 December 2021

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Articles

Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation

David M. Wood, Renwick C.J. Dobson, Christopher R. Horne

Biochem Soc Trans (2021) 49 (6): 2711–2726.

DOI: https://doi.org/10.1042/BST20210674

Published: 02 December 2021

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Articles

Pluripotency transcription factors at the focus: the phase separation paradigm in stem cells

Camila Oses, Martin Stortz, Paula Verneri, Alejandra Guberman, Valeria Levi

Biochem Soc Trans (2021) 49 (6): 2871–2878.

DOI: https://doi.org/10.1042/BST20210856

Published: 23 November 2021

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Articles

Live-cell visualization of cytochrome c : a tool to explore apoptosis

João Pessoa

Biochem Soc Trans (2021) 49 (6): 2903–2915.

DOI: https://doi.org/10.1042/BST20211028

Published: 08 November 2021

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Articles

TOP2B's contributions to transcription

Caroline A. Austin, Ian G. Cowell, Mushtaq M. Khazeem, Dawn Lok, Huei Teng Ng

Biochem Soc Trans (2021) 49 (6): 2483–2493.

DOI: https://doi.org/10.1042/BST20200454

Published: 08 November 2021

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Articles

LUBAC: a new player in polyglucosan body disease

Andrew Aboujaoude, Berge Minassian, Sharmistha Mitra

Biochem Soc Trans (2021) 49 (5): 2443–2454.

DOI: https://doi.org/10.1042/BST20210838

Published: 28 October 2021

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Articles

To export, or not to export: how nuclear export factor variants resolve Piwi's dilemma

Sheng Wang, Xiaohua Lu, Ding Qiu, Yang Yu

Biochem Soc Trans (2021) 49 (5): 2073–2079.

DOI: https://doi.org/10.1042/BST20201171

Published: 13 October 2021

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Articles

Biophysical characterisation of SMALPs

Stephanie A. Nestorow, Tim R. Dafforn, Verna Frasca

Biochem Soc Trans (2021) 49 (5): 2037–2050.

DOI: https://doi.org/10.1042/BST20201088

Published: 13 October 2021

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Articles

Targeting small GTPases and their downstream pathways with intracellular macromolecule binders to define alternative therapeutic strategies in cancer

Marie Sorbara, Nicolas Bery

Biochem Soc Trans (2021) 49 (5): 2021–2035.

DOI: https://doi.org/10.1042/BST20201059

Published: 08 October 2021

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Articles

An integrated view of innate immune mechanisms in C. elegans

Benjamin W. Harding, Jonathan J. Ewbank

Biochem Soc Trans (2021) 49 (5): 2307–2317.

DOI: https://doi.org/10.1042/BST20210399

Published: 08 October 2021

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Articles

How activated NLRs induce anti-microbial defenses in plants

Farid El Kasmi

Biochem Soc Trans (2021) 49 (5): 2177–2188.

DOI: https://doi.org/10.1042/BST20210242

Published: 08 October 2021

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Articles

Our evolving understanding of the role of the γδ T cell receptor in γδ T cell mediated immunity

Benjamin S. Gully, Jamie Rossjohn, Martin S. Davey

Biochem Soc Trans (2021) 49 (5): 1985–1995.

DOI: https://doi.org/10.1042/BST20200890

Published: 13 September 2021

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Articles

Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer

Erinna F. Lee, W. Douglas Fairlie

Biochem Soc Trans (2021) 49 (5): 2381–2395.

DOI: https://doi.org/10.1042/BST20210749

Published: 13 September 2021

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Articles

The role of pro-domains in human growth factors and cytokines

Matthew Ratcliff, Richard Xu Zhou, Lutz Jermutus, Marko Hyvönen

Biochem Soc Trans (2021) 49 (5): 1963–1973.

DOI: https://doi.org/10.1042/BST20200663

Published: 08 September 2021

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Articles

Post-translational modifications and stabilization of microtubules regulate transport of viral factors during infections

Silvia Requena, Francisco Sánchez-Madrid, Noa B. Martín-Cófreces

Biochem Soc Trans (2021) 49 (4): 1735–1748.

DOI: https://doi.org/10.1042/BST20210017

Published: 26 August 2021

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Articles

Profiling novel pharmacology of receptor complexes using Receptor-HIT

Elizabeth K.M. Johnstone, Kevin D.G. Pfleger

Biochem Soc Trans (2021) 49 (4): 1555–1565.

DOI: https://doi.org/10.1042/BST20201110

Published: 26 August 2021

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Articles

The influence of lipid digestion on the fate of orally administered drug delivery vehicles

Ben J. Boyd, Andrew J. Clulow

Biochem Soc Trans (2021) 49 (4): 1749–1761.

DOI: https://doi.org/10.1042/BST20210168

Published: 25 August 2021

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Articles

Lipid–protein interactions in virus assembly and budding from the host cell plasma membrane

Balindile B. Motsa, Robert V. Stahelin

Biochem Soc Trans (2021) 49 (4): 1633–1641.

DOI: https://doi.org/10.1042/BST20200854

Published: 25 August 2021

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Articles

Microglia extracellular vesicles: focus on molecular composition and biological function

Lorenzo Ceccarelli, Chiara Giacomelli, Laura Marchetti, Claudia Martini

Biochem Soc Trans (2021) 49 (4): 1779–1790.

DOI: https://doi.org/10.1042/BST20210202

Published: 20 August 2021

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Articles

Methods for the solubilisation of membrane proteins: the micelle-aneous world of membrane protein solubilisation

Giedre Ratkeviciute, Benjamin F. Cooper, Timothy J. Knowles

Biochem Soc Trans (2021) 49 (4): 1763–1777.

DOI: https://doi.org/10.1042/BST20210181

Published: 20 August 2021

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Articles

Extracellular Hsp90 and protection of neuronal cells through Nrf2

Stuart K. Calderwood, Thiago J. Borges, Takanori Eguchi, Benjamin J. Lang, Ayesha Murshid, Yuka Okusha, Thomas L. Prince

Biochem Soc Trans (2021) 49 (5): 2299–2306.

DOI: https://doi.org/10.1042/BST20210370

Published: 20 August 2021

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Articles

Unravelling the structural complexity of protein–lipid interactions with neutron reflectometry

Luke A. Clifton

Biochem Soc Trans (2021) 49 (4): 1537–1546.

DOI: https://doi.org/10.1042/BST20201071

Published: 09 July 2021

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Articles

Utilizing magnetic resonance techniques to study membrane interactions of amyloid peptides

Sunnia Rajput, Marc-Antoine Sani, David W. Keizer, Frances Separovic

Biochem Soc Trans (2021) 49 (3): 1457–1465.

DOI: https://doi.org/10.1042/BST20201244

Published: 22 June 2021

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Articles

Protein-fragment complementation assays for large-scale analysis of protein–protein interactions

Ewa Blaszczak, Natalia Lazarewicz, Aswani Sudevan, Robert Wysocki, Gwenaël Rabut

Biochem Soc Trans (2021) 49 (3): 1337–1348.

DOI: https://doi.org/10.1042/BST20201058

Published: 22 June 2021

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Articles

The HSP70 chaperone as sensor of the NEDD8 cycle upon DNA damage

Aymeric P. Bailly, Dimitris P. Xirodimas

Biochem Soc Trans (2021) 49 (3): 1075–1083.

DOI: https://doi.org/10.1042/BST20200381

Published: 22 June 2021

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Articles

The expanding world of metabolic enzymes moonlighting as RNA binding proteins

Nicole J. Curtis, Constance J. Jeffery

Biochem Soc Trans (2021) 49 (3): 1099–1108.

DOI: https://doi.org/10.1042/BST20200664

Published: 10 June 2021

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Articles

Bacteria autoaggregation: how and why bacteria stick together

El-shama Q. A. Nwoko, Iruka N. Okeke

Biochem Soc Trans (2021) 49 (3): 1147–1157.

DOI: https://doi.org/10.1042/BST20200718

Published: 10 June 2021

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Includes: Supplementary data

Articles

Biological insights from SMA-extracted proteins

Lucas Unger, Alejandro Ronco-Campaña, Philip Kitchen, Roslyn M. Bill, Alice J. Rothnie

Biochem Soc Trans (2021) 49 (3): 1349–1359.

DOI: https://doi.org/10.1042/BST20201067

Published: 10 June 2021

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The role of splicing factors in retinitis pigmentosa: links to cilia

Dale W. Maxwell, Raymond T. O'Keefe, Sudipto Roy, Kathryn E. Hentges

Biochem Soc Trans (2021) 49 (3): 1221–1231.

DOI: https://doi.org/10.1042/BST20200798

Published: 01 June 2021

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YbeY, éminence grise of ribosome biogenesis

Zhen Liao, Cédric Schelcher, Alexandre Smirnov

Biochem Soc Trans (2021) 49 (2): 727–745.

DOI: https://doi.org/10.1042/BST20200669

Published: 30 April 2021

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Regulation of MST complexes and activity via SARAH domain modifications

Sofiia Karchugina, Dorothy Benton, Jonathan Chernoff

Biochem Soc Trans (2021) 49 (2): 675–683.

DOI: https://doi.org/10.1042/BST20200559

Published: 16 April 2021

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