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Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins

Nadezhda A. Aleksandrova, Solace G. Roche, Yu Shang Low, Michael J. Landsberg

Biochem Soc Trans (2023) BST20221409.

DOI: https://doi.org/10.1042/BST20221409

Published: 18 May 2023

View article titled, Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins

Articles

Nesprin-1: novel regulator of striated muscle nuclear positioning and mechanotransduction

Shanelle De Silva, Zhijuan Fan, Baoqiang Kang, Catherine M. Shanahan, Qiuping Zhang

Biochem Soc Trans (2023) BST20221541.

DOI: https://doi.org/10.1042/BST20221541

Published: 12 May 2023

View article titled, Nesprin-1: novel regulator of striated muscle nuclear positioning and mechanotransduction

Articles

The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?

Chloe Girard, David Zwicker, Raphael Mercier

Biochem Soc Trans (2023) BST20221329.

DOI: https://doi.org/10.1042/BST20221329

Published: 05 May 2023

View article titled, The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?

Includes: Multimedia, Supplementary data

Articles

The molecular mechanisms of the bacterial iron sensor IdeR

Francisco Javier Marcos-Torres, Linda Juniar, Julia J. Griese

Biochem Soc Trans (2023) BST20221539.

DOI: https://doi.org/10.1042/BST20221539

Published: 04 May 2023

View article titled, The molecular mechanisms of the bacterial iron sensor IdeR

Articles

Redox-regulated chaperones in cell stress responses

Kathrin Ulrich

Biochem Soc Trans (2023) BST20221304.

DOI: https://doi.org/10.1042/BST20221304

Published: 04 May 2023

View article titled, Redox-regulated chaperones in cell stress responses

Articles

Single-molecule tracking (SMT): a window into live-cell transcription biochemistry

Liza Dahal, Nike Walther, Robert Tjian, Xavier Darzacq, Thomas G.W. Graham

Biochem Soc Trans (2023) 51 (2): 557–569.

DOI: https://doi.org/10.1042/BST20221242

Published: 06 March 2023

View article titled, Single-molecule tracking (SMT): a window into live-cell transcription biochemistry

Articles

Mitochondrial dynamics in macrophages: divide to conquer or unite to survive?

Syeda Farhana Afroz, Karoline D. Raven, Grace M.E.P. Lawrence, Ronan Kapetanovic, Kate Schroder, Matthew J. Sweet

Biochem Soc Trans (2023) 51 (1): 41–56.

DOI: https://doi.org/10.1042/BST20220014

Published: 23 February 2023

View article titled, Mitochondrial dynamics in macrophages: divide to conquer or unite to survive?

Articles

The role of CaMKK2 in Golgi-associated vesicle trafficking

Grace Kennedy, Olivia Gibson, Dáire T. O'Hare, Ian G. Mills, Emma Evergren

Biochem Soc Trans (2023) 51 (1): 331–342.

DOI: https://doi.org/10.1042/BST20220833

Published: 23 February 2023

View article titled, The role of CaMKK2 in Golgi-associated vesicle trafficking

Articles

Allosteric regulation and inhibition of protein kinases

Victoria R. Mingione, YiTing Paung, Ian R. Outhwaite, Markus A. Seeliger

Biochem Soc Trans (2023) 51 (1): 373–385.

DOI: https://doi.org/10.1042/BST20220940

Published: 16 February 2023

View article titled, Allosteric regulation and inhibition of protein kinases

Articles

Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM

Florian Fäßler, Manjunath G. Javoor, Florian KM Schur

Biochem Soc Trans (2023) 51 (1): 87–99.

DOI: https://doi.org/10.1042/BST20220221

Published: 25 January 2023

View article titled, Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM

Articles

The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder

Katerina Cermakova, Vaclav Veverka, H. Courtney Hodges

Biochem Soc Trans (2023) 51 (1): 125–135.

DOI: https://doi.org/10.1042/BST20220342

Published: 18 January 2023

View article titled, The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder

Articles

From seeds to trees: how E2 enzymes grow ubiquitin chains

Adam J. Middleton, Catherine L. Day

Biochem Soc Trans (2023) 51 (1): 353–362.

DOI: https://doi.org/10.1042/BST20220880

Published: 16 January 2023

View article titled, From seeds to trees: how E2 enzymes grow ubiquitin chains

Articles

The dynamic balance of the skin microbiome across the lifespan

Elizabeth C. Townsend, Lindsay R. Kalan

Biochem Soc Trans (2023) 51 (1): 71–86.

DOI: https://doi.org/10.1042/BST20220216

Published: 06 January 2023

View article titled, The dynamic balance of the skin microbiome across the lifespan

Articles

Interactions governing transcriptional activity of nuclear receptors

Sabab Hasan Khan, C. Denise Okafor

Biochem Soc Trans (2022) 50 (6): 1941–1952.

DOI: https://doi.org/10.1042/BST20220338

Published: 16 December 2022

View article titled, Interactions governing transcriptional activity of nuclear receptors

Articles

The mechanisms of chromogranin B-regulated Cl − homeostasis

Qiu-Xing Jiang, Gaya Yadav

Biochem Soc Trans (2022) 50 (6): 1659–1672.

DOI: https://doi.org/10.1042/BST20220435

Published: 13 December 2022

View article titled, The mechanisms of chromogranin B-regulated Cl − homeostasis

Articles

Placental extracellular vesicles in maternal-fetal communication during pregnancy

Charlène Martin, Mathilde Bergamelli, Cécile E. Malnou, Gisela D'Angelo

Biochem Soc Trans (2022) 50 (6): 1785–1795.

DOI: https://doi.org/10.1042/BST20220734

Published: 09 December 2022

View article titled, Placental extracellular vesicles in maternal-fetal communication during pregnancy

Articles

Deciphering the mechanism and function of Hsp100 unfoldases from protein structure

Grace Lee, Rebecca S. Kim, Sang Bum Lee, Sukyeong Lee, Francis T.F. Tsai

Biochem Soc Trans (2022) 50 (6): 1725–1736.

DOI: https://doi.org/10.1042/BST20220590

Published: 01 December 2022

View article titled, Deciphering the mechanism and function of Hsp100 unfoldases from protein structure

Articles

The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI

Dmitry Lyumkis, Nancy C. Horton

Biochem Soc Trans (2022) 50 (6): 1703–1714.

DOI: https://doi.org/10.1042/BST20220547

Published: 18 November 2022

View article titled, The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI

Articles

The role of UV-DDB in processing 8-oxoguanine during base excision repair

Ashna Nagpal, Sripriya Raja, Bennett Van Houten

Biochem Soc Trans (2022) 50 (5): 1481–1488.

DOI: https://doi.org/10.1042/BST20220748

Published: 28 October 2022

View article titled, The role of UV-DDB in processing 8-oxoguanine during base excision repair

Articles

A comprehensive review of methods to study lncRNA–protein interactions in solution

Maulik D. Badmalia, Higor Sette Pereira, M. Quadir Siddiqui, Trushar R. Patel

Biochem Soc Trans (2022) 50 (5): 1415–1426.

DOI: https://doi.org/10.1042/BST20220604

Published: 17 October 2022

View article titled, A comprehensive review of methods to study lncRNA–protein interactions in solution

Articles

Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT

Theresa M. Smith, Barry M. Willardson

Biochem Soc Trans (2022) 50 (5): 1403–1414.

DOI: https://doi.org/10.1042/BST20220591

Published: 05 October 2022

View article titled, Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT

Articles

Protective HLA-B57: T cell and natural killer cell recognition in HIV infection

Christian A. Lobos, Jonathan Downing, Lloyd J. D'Orsogna, Demetra S.M. Chatzileontiadou, Stephanie Gras

Biochem Soc Trans (2022) 50 (5): 1329–1339.

DOI: https://doi.org/10.1042/BST20220244

Published: 16 September 2022

View article titled, Protective HLA-B57: T cell and natural killer cell recognition in HIV infection

Articles

The role of RHIM in necroptosis

In Collection

Cell death and survival

Theresa Riebeling, Ulrich Kunzendorf, Stefan Krautwald

Biochem Soc Trans (2022) 50 (4): 1197–1205.

DOI: https://doi.org/10.1042/BST20220535

Published: 30 August 2022

View article titled, The role of RHIM in necroptosis

Articles

LILBID-MS: using lasers to shed light on biomolecular architectures

Nils Hellwig, Janosch Martin, Nina Morgner

Biochem Soc Trans (2022) 50 (3): 1057–1067.

DOI: https://doi.org/10.1042/BST20190881

Published: 13 June 2022

View article titled, LILBID-MS: using lasers to shed light on biomolecular architectures

Articles

CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact

Takahiro Ishizaki, Sophia Hernandez, Martina S. Paoletta, Theo Sanderson, Ellen S.C. Bushell

Biochem Soc Trans (2022) 50 (3): 1069–1079.

DOI: https://doi.org/10.1042/BST20210281

Published: 27 May 2022

View article titled, CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact

Articles

AAA+ proteins: one motor, multiple ways to work

JiaBei Lin, James Shorter, Aaron L. Lucius

Biochem Soc Trans (2022) 50 (2): 895–906.

DOI: https://doi.org/10.1042/BST20200350

Published: 31 March 2022

View article titled, AAA+ proteins: one motor, multiple ways to work

Articles

MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Steven R. Van Doren

Biochem Soc Trans (2022) 50 (2): 839–851.

DOI: https://doi.org/10.1042/BST20210640

Published: 28 March 2022

View article titled, MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Articles

PIDD1 in cell cycle control, sterile inflammation and cell death

In Collection

Cell death and survival

Elias S. Weiler, Tamas G. Szabo, Irmina Garcia-Carpio, Andreas Villunger

Biochem Soc Trans (2022) 50 (2): 813–824.

DOI: https://doi.org/10.1042/BST20211186

Published: 28 March 2022

View article titled, PIDD1 in cell cycle control, sterile inflammation and cell death

Articles

Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?

Ekaterina Shevchenko, Tatu Pantsar

Biochem Soc Trans (2022) 50 (1): 633–648.

DOI: https://doi.org/10.1042/BST20210837

Published: 28 February 2022

View article titled, Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?

Articles

Exploring cryo-electron microscopy with molecular dynamics

John W. Vant, Daipayan Sarkar, Jonathan Nguyen, Alexander T. Baker, Josh V. Vermaas, Abhishek Singharoy

Biochem Soc Trans (2022) 50 (1): 569–581.

DOI: https://doi.org/10.1042/BST20210485

Published: 25 February 2022

View article titled, Exploring cryo-electron microscopy with molecular dynamics

Articles

IMPDH dysregulation in disease: a mini review

Anika L. Burrell, Justin M. Kollman

Biochem Soc Trans (2022) 50 (1): 71–82.

DOI: https://doi.org/10.1042/BST20210446

Published: 22 February 2022

View article titled, IMPDH dysregulation in disease: a mini review

Articles

Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin

Luke T. Marr, Prasoon Jaya, Laxmi N. Mishra, Jeffrey J. Hayes

Biochem Soc Trans (2022) 50 (1): 199–212.

DOI: https://doi.org/10.1042/BST20210959

Published: 15 February 2022

View article titled, Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin

Articles

Control of non-productive RNA polymerase II transcription via its early termination in metazoans

Jérôme O. Rouvière, Søren Lykke-Andersen, Torben Heick Jensen

Biochem Soc Trans (2022) 50 (1): 283–295.

DOI: https://doi.org/10.1042/BST20201140

Published: 15 February 2022

View article titled, Control of non-productive RNA polymerase II transcription via its early termination in metazoans

Articles

Inferiority complex: why do sensory ion channels multimerize?

Nikita Gamper, Shihab Shah

Biochem Soc Trans (2022) 50 (1): 213–222.

DOI: https://doi.org/10.1042/BST20211002

Published: 15 February 2022

View article titled, Inferiority complex: why do sensory ion channels multimerize?

Articles

Multiple roles of Pol epsilon in eukaryotic chromosome replication

Milos A. Cvetkovic, Esther Ortega, Roberto Bellelli, Alessandro Costa

Biochem Soc Trans (2022) 50 (1): 309–320.

DOI: https://doi.org/10.1042/BST20210082

Published: 07 February 2022

View article titled, Multiple roles of Pol epsilon in eukaryotic chromosome replication

Articles

Mechanism of action of nucleotide excision repair machinery

Areetha D'Souza, Alexandra M. Blee, Walter J. Chazin

Biochem Soc Trans (2022) 50 (1): 375–386.

DOI: https://doi.org/10.1042/BST20210246

Published: 25 January 2022

View article titled, Mechanism of action of nucleotide excision repair machinery

Articles

Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)

Jai Woo Lee, Miguel A. Maria-Solano, Thi Ngoc Lan Vu, Sanghee Yoon, Sun Choi

Biochem Soc Trans (2022) 50 (1): 241–252.

DOI: https://doi.org/10.1042/BST20211240

Published: 25 January 2022

View article titled, Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)

Articles

Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Matthew J. A. Hein, Marc Kvansakul, Fung T. Lay, Thanh Kha Phan, Mark D. Hulett

Biochem Soc Trans (2022) 50 (1): 423–437.

DOI: https://doi.org/10.1042/BST20200884

Published: 11 January 2022

View article titled, Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Articles

Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Jorge Ripoll-Rozada, Joshua W. C. Maxwell, Richard J. Payne, Pedro José Barbosa Pereira

Biochem Soc Trans (2022) 50 (1): 387–401.

DOI: https://doi.org/10.1042/BST20210600

Published: 07 January 2022

View article titled, Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Articles

The role of caspases as executioners of apoptosis

In Collection

Cell death and survival

Sharad Kumar, Loretta Dorstyn, Yoon Lim

Biochem Soc Trans (2022) 50 (1): 33–45.

DOI: https://doi.org/10.1042/BST20210751

Published: 23 December 2021

View article titled, The role of caspases as executioners of apoptosis

Articles

HSP90 as a regulator of extracellular matrix dynamics

Abir Chakraborty, Adrienne Lesley Edkins

Biochem Soc Trans (2021) 49 (6): 2611–2625.

DOI: https://doi.org/10.1042/BST20210374

Published: 16 December 2021

View article titled, HSP90 as a regulator of extracellular matrix dynamics

Articles

VDAC2 and the BCL-2 family of proteins

In Collection

Cell death and survival

Zheng Yuan, Grant Dewson, Peter E. Czabotar, Richard W. Birkinshaw

Biochem Soc Trans (2021) 49 (6): 2787–2795.

DOI: https://doi.org/10.1042/BST20210753

Published: 16 December 2021

View article titled, VDAC2 and the BCL-2 family of proteins

Articles

How a cell decides its own fate: a single-cell view of molecular mechanisms and dynamics of cell-type specification

Maria Mircea, Stefan Semrau

Biochem Soc Trans (2021) 49 (6): 2509–2525.

DOI: https://doi.org/10.1042/BST20210135

Published: 02 December 2021

View article titled, How a cell decides its own fate: a single-cell view of molecular mechanisms and dynamics of cell-type specification

Articles

Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation

David M. Wood, Renwick C.J. Dobson, Christopher R. Horne

Biochem Soc Trans (2021) 49 (6): 2711–2726.

DOI: https://doi.org/10.1042/BST20210674

Published: 02 December 2021

View article titled, Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation

Articles

Pluripotency transcription factors at the focus: the phase separation paradigm in stem cells

Camila Oses, Martin Stortz, Paula Verneri, Alejandra Guberman, Valeria Levi

Biochem Soc Trans (2021) 49 (6): 2871–2878.

DOI: https://doi.org/10.1042/BST20210856

Published: 23 November 2021

View article titled, Pluripotency transcription factors at the focus: the phase separation paradigm in stem cells

Articles

Live-cell visualization of cytochrome c : a tool to explore apoptosis

João Pessoa

Biochem Soc Trans (2021) 49 (6): 2903–2915.

DOI: https://doi.org/10.1042/BST20211028

Published: 08 November 2021

View article titled, Live-cell visualization of cytochrome c : a tool to explore apoptosis

Articles

TOP2B's contributions to transcription

Caroline A. Austin, Ian G. Cowell, Mushtaq M. Khazeem, Dawn Lok, Huei Teng Ng

Biochem Soc Trans (2021) 49 (6): 2483–2493.

DOI: https://doi.org/10.1042/BST20200454

Published: 08 November 2021

View article titled, TOP2B's contributions to transcription

Articles

LUBAC: a new player in polyglucosan body disease

Andrew Aboujaoude, Berge Minassian, Sharmistha Mitra

Biochem Soc Trans (2021) 49 (5): 2443–2454.

DOI: https://doi.org/10.1042/BST20210838

Published: 28 October 2021

View article titled, LUBAC: a new player in polyglucosan body disease

Articles

To export, or not to export: how nuclear export factor variants resolve Piwi's dilemma

Sheng Wang, Xiaohua Lu, Ding Qiu, Yang Yu

Biochem Soc Trans (2021) 49 (5): 2073–2079.

DOI: https://doi.org/10.1042/BST20201171

Published: 13 October 2021

View article titled, To export, or not to export: how nuclear export factor variants resolve Piwi's dilemma

Articles

Biophysical characterisation of SMALPs

Stephanie A. Nestorow, Tim R. Dafforn, Verna Frasca

Biochem Soc Trans (2021) 49 (5): 2037–2050.

DOI: https://doi.org/10.1042/BST20201088

Published: 13 October 2021

View article titled, Biophysical characterisation of SMALPs

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